
Places to stay near Buffalo Museum of Science
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Top-rated vacation rentals near Buffalo Museum of Science
Guests agree: these stays are highly rated for location, cleanliness, and more.

LarkinVille Loft (Unit 1)
Welcome to Larkinville! A lively but quaint neighborhood with walkable restaurants, shops, breweries and is pretty much 20 minuets from everywhere in Buffalo and our surrounding suburbs. Unit 1 is located on the 1st floor of a 2 story, 5 unit apartment building sitting on a corner lot. Guests get 1 off street parking spot and access to the shared side yard. Detailed information on the apartment can be found below. Please feel free to reach out regarding extended stay discounts.
4.94 out of 5 average rating, 765 reviews
Home away from home
Sunny Urban Retreat with two bedrooms Welcome to my delightful upstairs apartment. This sun-kissed haven offers, comfort & convenience. highlights: Two bedrooms rest easy in the spacious primary bedroom in a queen- size bed or choose the cozy second bedroom with a full-size bed. The kitchen features a stove, refrigerator and microwave. Location: situated just one mile from the medical corridor. Buffalo's vibrant theater district and Canalside are 3 miles away. Niagara Falls awaits 21 miles.
4.85 out of 5 average rating, 192 reviews
Sunlit Serenity on Pearl: 2-BR in Downtown Buffalo
Welcome to your private oasis on Pearl Street — where modern elegance meets effortless comfort. Bathed in natural light and upscale finishes, this refined 2BR offers a sophisticated stay. Situated in the heart of downtown, you're steps away from Buffalo’s best dining, nightlife, and entertainment. Enjoy walkable access to: Shea’s Theater, 500 Pearl, Town Ballroom, Electric City, Convention Center etc! - 5 mins to Sahlen Field (Bisons) & Keybank (Sabres) - 20 mins to Highmark Stadium (Bills)
4.96 out of 5 average rating, 118 reviews
Bright, Beautiful Lakefront @ Historical Fort Erie
Come home to relax in our beautifully decorated lakefront escape in the sweet town of Fort Erie. Our home is a large open concept with a smart TV, free Wi-Fi, fully equipped kitchen, 3 clean & comfortable bedrooms, 2.5 bathrooms and everything else you need for your perfect vacation. You'll be located across the street from the lake and a 2 minute walk to the old fort. Enjoy a stroll (or bike) along the lakeside path into old Fort Erie where you will find shops and fine restaurants or pubs.
4.95 out of 5 average rating, 180 reviews
Spacious Historical Home by Parks, Shops, 4bd 2ba
Enjoy the unique charm of this 2,200 sq ft historic home. Gather in the light-filled, open living area featuring century-old woodwork, or cook together in the fully equipped kitchen. Upstairs, 4 roomy bedrooms comfortably sleep 8. Whether you need to catch up on remote work in the quiet office, unwind in the dedicated Zen room, or grill on the private patio, there’s space for everyone. Best of all, you’re just 7 minutes from downtown and 15 from the airport. Book your seamless stay today!
4.89 out of 5 average rating, 164 reviews
Homey Private Penthouse
This cozy, centrally-located studio/1BR is in the heart of Allentown. It is 2 blocks from the new medical campus, five minutes from downtown, five minutes from Elmwood Village, and two minutes from all the bars of Allentown. It is across the street from many of the shops in Allentown. We are passionate about Buffalo and would love to host you and help make your Buffalo experience special. FYI, the unit can be noisy at night, especially on the weekend, and is on the third floor.
4.93 out of 5 average rating, 118 reviews
Five Points Apartment- Upper Unit
Updated Upper Unit Apartment. Great City Location! Walking Distance to Five Points, and Lower West Side Restaurants and Shops. Off Street Parking (when available). In Unit Laundry. WiFi. Pets Allowed ($50 pet fee). Queen Bed and Fold Down Futon. Blocks from D’Youville University and minutes from Buffalo State University! Close to Kleinhans Music Hall, Elmwood Village and Allentown! 10 Min Drive To KeyBank Center - 20 Min Drive To Highmark Stadium - 20 Min Drive To Niagara Falls
4.87 out of 5 average rating, 272 reviews
Private 3-bedroom cottage at St. Patrick's Friary
Newly renovated private cottage on the historic grounds of Buffalo's first Irish Catholic church complex in the popular Larkinville area of Buffalo. Only a 7-minute drive from downtown/RiverWorks/Canalside, and 1 minute walk to Larkin Square, there are plenty of restaurants, breweries and attractions nearby. This cottage has a beautiful flower garden and fresh herbs you can pick and use while grilling on the patio. There is a washer and dryer in the garage.
4.95 out of 5 average rating, 282 reviews
Suite Studio ❤️️ (Free Parking, Elmwood Village!)
Sunny bright central location. This studio is equipped with all you need. Just 30 minutes to Niagara Falls,and 30 minutes to New Era (Buffalo Bills) stadium, we're right in the middle of all the fun! Located just steps away from Delaware Park, Forest Lawn Cemetery, and Elmwood Village, we are within walking distance of some of the locals' favorite spots. We've got it all with safe, secure, off street private parking, quiet & clean, in the best spot!
4.79 out of 5 average rating, 692 reviews
Steps to the Beach + Lakeviews + HotTub + Elevator
Unwind at this The Red Lakehouse just steps from the beach, featuring a private hot tub, fire pit, and covered balcony with Lake Erie views. Perfect for families, groups, and getaways, this professionally designed home offers 3 bedrooms with private ensuites for ultimate comfort and privacy. Minutes to Niagara Falls, Crystal Beach, and the USA border — yet tucked in a quiet, relaxing neighbourhood. A spotless, thoughtfully curated stay.
4.96 out of 5 average rating, 162 reviews
Historic Mansion Built in 1896, Pan Am. Expo Era
Allow our home to be your home for your next visit to Buffalo. Summer Street Guest House was built for entertaining. This gracious old mansion is filled with warmth and love. Each room has its own glow. We occupy the third floor. The large living room, dinning room and kitchen on the first floor and four large bedrooms on the second floor are available for your enjoyment.
4.79 out of 5 average rating, 140 reviews
Cozy & Walkable Elmwood Village Charmer
This charming lower unit is ideally located between vibrant Elmwood Village and the up-and-coming West Side. Walk to shops, cafés, bars, and restaurants — just six blocks from Elmwood Ave. Nearby: • Buffalo Airport – 15 min drive • Niagara Falls – 30 min drive • Canada – 10 min drive • Downtown – 10 min drive • Allentown – 5 min drive • Bills Stadium – 25 min drive
4.9 out of 5 average rating, 417 reviewsPopular amenities for vacation rentals near Buffalo Museum of Science
Condo rentals with wifi

Quiet nice and clean apartment downtown Buffalo
4.93 out of 5 average rating, 261 reviews
Skyline Square Condo
4.93 out of 5 average rating, 153 reviews
The Eugene
4.91 out of 5 average rating, 564 reviews
NEW Luxurious 2BR Condo Free Parking Niagara Falls
4.91 out of 5 average rating, 236 reviews
Modern Niagara Falls Condo
4.86 out of 5 average rating, 304 reviews
Entire Condo Minutes from Niagara Falls (USA)
4.79 out of 5 average rating, 694 reviews
Chic Contemporary 2 Bed| 5 Mins to the falls
4.87 out of 5 average rating, 166 reviews
Cozy 2-Bedroom Condo with Parking in Niagara Falls
4.88 out of 5 average rating, 112 reviewsFamily-friendly house rentals

Architectural Urban Escape: Checking all the boxes
5.0 out of 5 average rating, 139 reviews
Oasis | Patio, Pool, NEW Putting Green, Fire Pit
4.97 out of 5 average rating, 144 reviews
Treasure Tree
4.94 out of 5 average rating, 115 reviews
Down town Buffalo, Entire house
4.96 out of 5 average rating, 257 reviews
Beautiful Victorian House
4.83 out of 5 average rating, 200 reviews
Cornerhouse716 - Modern NEW BUILD in central spot!
4.98 out of 5 average rating, 102 reviews
Massive Architecturally Amazing Grand Victorian
4.93 out of 5 average rating, 155 reviews
The Italianate: Historic Home w/ Sauna and Firepit
4.9 out of 5 average rating, 196 reviewsApartment rentals with air conditioning

Historic Apartment Steps Away from Allentown Area
4.84 out of 5 average rating, 333 reviews
Spacious Private Retreat with Kitchen
4.93 out of 5 average rating, 218 reviews
Spacious 3 Bed Delaware Art Park Apartment
4.99 out of 5 average rating, 181 reviews
Elegant Elmwood Village Hideaway-New Outdoor Patio
4.96 out of 5 average rating, 183 reviews
Lovely 2-Bedroom Apartment in North Buffalo
4.92 out of 5 average rating, 253 reviews
Cozy Carriage House on Elmwood
4.98 out of 5 average rating, 315 reviews
Freshly Renovated 2 Bedroom
4.85 out of 5 average rating, 168 reviews
Inspiring Oasis · Walkable heart of City •AC
4.92 out of 5 average rating, 158 reviewsOther great vacation rentals near Buffalo Museum of Science

Sleep Under The Stars
4.99 out of 5 average rating, 1061 reviews
Moh.J Home Sweet Home
4.91 out of 5 average rating, 138 reviews
Modern Trendy Downtown
4.85 out of 5 average rating, 114 reviews
Hidden Parkside Carriage House near everything.
4.99 out of 5 average rating, 257 reviews
2bed apt, W/D, fireplace, balcony, pets
4.93 out of 5 average rating, 176 reviews
Cozy & Spacious Getaway! Centrally located.
4.94 out of 5 average rating, 125 reviews
2BD Log cabin in the heart of the city
4.89 out of 5 average rating, 101 reviews
Cozy 2 Bedroom Apt Close 2 Everything
4.98 out of 5 average rating, 147 reviewsDestinations to explore
- Letchworth State Park
- Six Flags Darien Lake
- Holiday Valley Ski Resort
- Niagara Falls
- Niagara Falls State Park
- Buffalo RiverWorks
- University at Buffalo North Campus
- Fallsview Indoor Waterpark
- Brock University
- Seneca Niagara Resort & Casino
- Keybank Center
- Vineland Estates Winery
- Jackson-Triggs Niagara Estate
- 13th Street Winery
- Kissing Bridge
- Fallsview Casino Resort
- Genesee Country Village and Museum
- Balls Falls Conservation Area
- Buffalo Zoo
- MarineLand
- Lakeside Park Carousel
- Buffalo and Erie County Botanical Gardens
- Canisius University
- Knox Farm State Park





