Places to stay near 21c Museum Hotel

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Top-rated vacation rentals near 21c Museum Hotel

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Top guest favorite
A vibrant garden entrance is framed by an arch covered in bright yellow flowers. Lush greenery surrounds a winding pathway, leading toward trees adorned with soft pink blooms and scattered outdoor seating beneath umbrellas. The scene evokes a serene outdoor retreat.
Apartment in Durham
4.98 out of 5 average rating, 1,122 reviews

2-BR apt/garden near downtown Durham arts & eats

A private, restful & artful 2-BR apt. hosted by one of fewer-than-20 Airbnb Belo Award winners in the world. 900 sq. ft. complete lower fl. of 1960s brick split-level on unpaved lane near park. Lush garden. Private entry; parking; lvng rm w/fireplace; bthrm/shwr; kitchenette only; generous amenities; wifi; TV. Superhost since 2014; 1,000 5-star reviews. 1 mi. DPAC/Durham Bulls; 1.5 mi. Carolina Theatre; 3 mi. Duke U/Med Cntr. No added cleaning fee. Host fully-vaccinated; same expected of guests.

Top guest favorite
A light-colored, two-story garage apartment is surrounded by a professionally landscaped garden, featuring diverse plants and a stone pathway. The structure showcases multiple windows that invite natural light, with a welcoming entrance under an overhang, framed by lush greenery.
Guesthouse in Durham
4.99 out of 5 average rating, 548 reviews

Light-filled Guesthouse Near Duke

Second floor of recently-built garage apartment in a charming, peaceful Durham neighborhood. Twenty minutes to RDU Airport, five minutes to Duke's East Campus and ten minutes to West Campus, we are an easy walk to a range of locally-owned restaurants. Lovely, light-filled apartment has a bedroom, full kitchen and living area, bathroom, private entrance, and patio with seating. Occasionally, we may have first-floor space available at extra cost. Well-behaved pets welcome. See below for fees.

Guest favorite
A spacious living area features a sleek gas fireplace on one side, with modern artwork displayed on the walls. Comfortable seating includes a large gray sofa and green accent chairs, accompanied by a round coffee table. Natural light floods in through large windows.
Home in Durham
4.95 out of 5 average rating, 104 reviews

Modernist Masterpiece: 'Simply the Best'

Welcome to Hazel Modernist 6 - designed and built by Alicia Hylton-Daniel, with her "sister," Modernist 5, next door. Centrally located downtown, this gorgeous escape is truly livable. Fully equipped chefs kitchen opens into the large living & dining space, with Frame TV and fireplace. 3BR & private back deck offer plenty of space together or alone. Each home by Alicia is infused with creative and new design concepts. This glamorous home celebrates the essence of Tina Turner, Simply the Best.

Superhost
A vibrant outdoor space features a green wall with the words 'Bull City' illuminated in neon pink. Seating arrangements with wooden chairs and a table are positioned on a textured wooden deck, offering an inviting area for relaxation.
Loft in Durham
4.97 out of 5 average rating, 150 reviews

Main St Studio w Rooftop Patio!

Literally right on Main St in downtown Durham! You'll be close to EVERYTHING! DPAC, Durham Bulls, Carolina Theater, amazing restaurants and cafes, American Tobacco Campus' stores, restaurants and unique walkway. It's all within 3 blocks! Enjoy sunrise OR sunset overlooking the famous Lucky Strike Water Tower from the cozy rooftop patio. Or stroll home in a matter of MINUTES from a baseball game or DPAC show. Perfectly appointed apartment w all you'll need to have a great and relaxing stay!

Guest favorite
A spacious living area features a gray sectional sofa and matching ottoman on polished hardwood floors. A flat-screen TV is mounted on the wall, and a dining table is positioned in the background. Soft lighting creates a cozy ambiance.
Apartment in Durham
4.95 out of 5 average rating, 358 reviews

Walk to Duke or Downtown- 1st floor

Beautiful, nicely furnished 1st floor apt in a quiet neighborhood between Duke and Downtown Durham, walkable to both. Very comfortable beds with high thread count scent free linens. Fully equipped kitchen and bathroom with organic body wash, shampoo, conditioner, blow dryer & make up mirror. 2 miles from Duke and VA Hospitals. 2 blocks from restaurants and the Organic Co-op grocery store. Lots of well lit parking on-site. We hope you'll love the comforts and convenience of staying her

Guest favorite
The tiny farmhouse features a welcoming front porch with two yellow chairs and multiple entrance doors. A covered seating area with a fire pit and an outdoor dining table is positioned on the gravel surface, surrounded by a fenced yard and lush greenery.
Tiny home in Durham
4.97 out of 5 average rating, 378 reviews

Tiny Farmhouse in the Heart of Durham

Enjoy the tiny experience without sacrificing the relaxations and comforts of home. Unwind in this quaint 1 bedroom 1 bath tiny farmhouse that’s equipped with full-sized appliances and tasteful amenities. The Farmhouse at Scout is nestled in Downtown Durham’s burgeoning Southside neighborhood and is extremely close to the best restaurants, shops, and activities that Durham has to offer. Major attractions: • DPAC: .8 mi • Durham Bulls: .8 mi • Farmer’s Market: 1.2 mi • Duke: 2.9 mi

Guest favorite
The studio's private entry is framed by a white wall. A sleek glass door is flanked by two modern outdoor light fixtures. A small seating area with a cushioned chair is visible to the left, while a sheer curtain adorns the adjacent window.
Guest suite in Durham
4.89 out of 5 average rating, 148 reviews

Private studio apartment steps from Downtown!

Compact studio steps from Downtown Durham with a private entry and free street parking! Well-stocked kitchenette and bathroom. Close to Duke and walkable to all of Downtown and more: ✦ 7+ coffee shops ✦ 10+ breweries ✦ Plenty of restaurants + bars ✦ DPAC, Durham Bulls + Durham Convention Center ✦ Central Park, Farmer's Market + Durham Food Hall ✦ Ellerbe Creek + American Tobacco Trails We live in the townhouse above the studio and are happy to assist with anything you might need.

Top guest favorite
A spacious living area features large glass walls allowing natural light and views of surrounding trees. A unique wood coffee table is centered on a light rug. Two comfortable sofas provide seating, paired with a modern lamp and elegant decor.
Home in Raleigh
4.96 out of 5 average rating, 179 reviews

Luxurious Modernist Tree House

Stunning, private, and truly one-of-a-kind—this unique home is perfect for a vacation, staycation, special occasion, or simply celebrating everyday life. Designed by renowned modernist architect Frank Harmon. The 2,128-square-foot residence sits on 1.3 acres and was crafted with meticulous attention to detail. Inside, you’ll feel nestled among the treetops while remaining conveniently close to restaurants, shopping, downtown Raleigh, WakeMed, UNC, Duke, and Research Triangle Park.

Top guest favorite
A modern tiny house is nestled among lush greenery, featuring large windows that invite natural light. A wooden pathway leads to the entrance, surrounded by a variety of plants and trees, creating a serene and secluded atmosphere.
Tiny home in Durham
4.96 out of 5 average rating, 622 reviews

Modern Tiny House Near Duke & Downtown

You’ll feel like you’re getting away from it all in this modern, private tiny house in the trees, even though you’re just minutes from Duke, downtown Durham, shopping, and restaurants. It’s the perfect balance of peaceful retreat and city convenience. The home includes all the essentials — full kitchen, laundry, A/C, and high-speed internet — but many guests find themselves spending most of their time relaxing on the screened-in porch, listening to birds, and recharging.

Guest favorite
A tiny house is depicted, featuring a bright blue exterior and a welcoming wooden deck. Surrounding trees provide shade, and a stone walkway leads to the entrance. The setting is lush with greenery, enhancing the serene atmosphere of the backyard escape.
Tiny home in Durham
4.96 out of 5 average rating, 271 reviews

Five & Dime Tiny House

Experience the charm of tiny living in this pet-friendly studio located in my serene yet urban backyard. It offers a peaceful escape while remaining convenient to the attractions & amenities that Durham has to offer. -only a mile east of downtown -1.5 miles to DPAC and Carolina Theatre -ten minutes to both Duke Hospital and Duke Regional -less than 20 minutes to RDU airport Let your dog run around the fully fenced yard while you sit on the deck and sip your coffee!

Guest favorite
A light-filled living area is showcased with large windows that offer views of greenery. A modern sofa adorned with colorful throw pillows is complemented by a round coffee table on a patterned area rug. The kitchen, featuring turquoise cabinetry, is visible in the background.
Guesthouse in Durham
4.94 out of 5 average rating, 127 reviews

Duplex filled with natural light

A stylish, modern, and beautiful alley guesthouse that is located just 2 blocks from Duke's East Campus and 4 blocks from downtown Durham. The apartment is located in the historic Trinity Park Neighborhood in Durham. The apartment has a top of the line finish, hardwood floors, appliances, and furniture. The loft area is equipped with a standing desk and monitor and 2 Yoga matts, and it is ideal for working professionals visiting the area. Built: 2023

Top guest favorite
A decorative pillow featuring two blue birds and a red heart is placed on a spacious bed. A cozy, textured throw blanket in neutral tones is draped nearby, contributing to a comfortable and inviting sleeping area.
Apartment in Durham
4.95 out of 5 average rating, 110 reviews

Garden Oasis in the heart of downtown Durham

Beautifully renovated must stay if visiting Durham downtown. Within walking distance of many restaurants and city sites. Close to Duke Medical and Campus, and a stone's throw from many of the great restaurants and activities downtown has to offer. Pearl mill (122) offers a secret garden courtyard, an oasis of serenity amongst the action of the city. Huge pool to enjoy, March through October, weather permitting.

Popular amenities for vacation rentals near 21c Museum Hotel