Hotel vacation rentals in South Carolina
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Top-rated hotel rentals in South Carolina
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for South Carolina hotel rentals
Family-friendly hotel rentals
Hotel room in Edisto Island
5 out of 5 average rating, 12 reviewsWyndham Ocean Ridge - Edisto Island ** 1 Bedroom
Resort in Hilton Head Island
5 out of 5 average rating, 4 reviewsOceanfront, Brand new Luxury Suite!!
Resort in Myrtle Beach
Myrtle Beach, Ocean Front Apt, July 7- July 14
Resort in Myrtle Beach
2 Bdrm - South Beach Resort - Myrtle Beach, SC
Hotel room in Charleston
4.77 out of 5 average rating, 47 reviewsCharming Historic Inn*
Private room in Myrtle Beach
5 out of 5 average rating, 4 reviews1 bdrm condo, South Beach Resort, Beach Access
Hotel room in Clemson
5 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Private room in Charleston
4.72 out of 5 average rating, 388 reviewsThe Goldman Room @ The Annex
Hotel rentals with a pool
Hotel room in Myrtle Beach
5 out of 5 average rating, 5 reviewsOceanview Condo. #2005
Pension in Myrtle Beach
4.67 out of 5 average rating, 21 reviewsLaurel Court 210 in Kingston resort, Pools & Beach
Private room in Pawleys Island
4.74 out of 5 average rating, 19 reviewsBubbles Up at Litchfield By The Sea
Private room in Myrtle Beach
4.83 out of 5 average rating, 40 reviewsOcean view condo @ The Palace
Hotel room in Folly Beach
5 out of 5 average rating, 8 reviewsFolliday Inn - The Triple - Room 24
Private room in Myrtle Beach
4.97 out of 5 average rating, 32 reviewsAmazing Ocean views! Pool, lazy river, hot tub
Private room in Myrtle Beach
4.77 out of 5 average rating, 77 reviewsCharming condo in Landmark hotel-Sleeps 4
Private room in Myrtle Beach
4.83 out of 5 average rating, 6 reviewsOceanfront paradise, waterpark, pools, 4 hot tubs
Hotel rentals with a patio
Casa particular in Charleston
5 out of 5 average rating, 4 reviewsPura Vida Unit 2- Modern Tiny Apartment Charleston
Casa particular in North Myrtle Beach
New place to stayCozy Oceanfront Condo
Casa particular in Hilton Head Island
New place to stayHeritage Classic 2025 Villa
Private room in Spartanburg
4.96 out of 5 average rating, 25 reviewsLovely 1 br/1 private bath.
Private room in Greenville County
4.89 out of 5 average rating, 9 reviewsCabin near Pretty Place!
Private room in Myrtle Beach
4.65 out of 5 average rating, 43 reviewsOceanfront Resort with a View - Freshly Renovated
Private room in Myrtle Beach
4.88 out of 5 average rating, 34 reviews2bd 2ba ocean view condo
Hotel room in Hilton Head Island
5 out of 5 average rating, 11 reviewsCharming Hilton Head Harbor Point Resort 2bd Suite
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