Vacation rentals in Scott County

Guesthouse in Cape Girardeau

A gravel parking area is presented in the foreground, accommodating a vehicle. Lush green grass surrounds the parking space, while a fence and trees provide a natural backdrop. A garage is visible in the distance, partially obscured by greenery.

4.92 out of 5 average rating, 110 reviews

Cozy 1-BR guest house w/free parking on premises

Enjoy a cozy experience at this centrally, located place. Literally, a 1-4 minute walk to Mercy Hospital(formerly Southeast Hospital), less than 1 mile to Southeast University Campus, along with downtown(river). A street over is Broadway with many restaurants. Walmart Market and Dollar General are also conveniently located nearby. The kitchen is fully furnished with cooking utensils, clean towels, pots and pans for those who prefer eating in. Please no animals and no smoking in the apartment.

A well-lit entryway features a wooden mirror above a small table, adorned with a gold-colored vase holding red flowers. A collection of magazines is neatly arranged beneath the vase. Soft, sheer curtains frame a window, allowing natural light to enhance the space.

4.98 out of 5 average rating, 414 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

4.82 out of 5 average rating, 113 reviews

A workspace is presented with a white desk and a contemporary black office chair. A softly glowing lamp adds illumination, while a window reveals a view of the private back deck. Natural light enhances the welcoming environment.

Home in Cape Girardeau

Herman’s Corner Cottage

Tucked in historic Cape Girardeau, this charming cottage offers comfort and convenience. Enjoy the cozy back deck with a privacy fence—perfect for relaxing or grilling. With ample off-street parking, your stay is stress-free. The home is equipped with essentials for a smooth, hassle-free visit. Book the entire house for added privacy, providing a peaceful retreat for you and your guests. Experience the perfect blend of comfort, affordability, and convenience during your Cape Girardeau getaway.

Guest suite in Cape Girardeau

A well-lit hallway features a round mirror above a dark dresser with a decorative tray and small plant. To the right, a door leads to another room, while wall hooks are visible for hanging items. A woven pendant light adds a soft glow.

4.97 out of 5 average rating, 151 reviews

MAINSTAY CAPE [downtown]

Nestled in the heart of the Downtown Historic District, this suite is centrally located as a prime destination for any and all travelers alike. With parking available, this space offers a unique & trendy “midwest boho” vibe. ~WALKABLE~ Our studio is 1 block from the bustling Southeast Missouri State University, 1 block from the gorgeous Capaha Park, and 2 blocks from Mercy Hospital. If you are interested in night life, this space is simply a 5-10 minute walk to all DT bars and restaurants.

A spacious deck features wooden flooring with a sleek surface, complemented by two black chairs. A circular white table sits between them, and a potted plant with vibrant flowers adds a touch of greenery to the space.

4.95 out of 5 average rating, 245 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

4.86 out of 5 average rating, 607 reviews

Unique Design | Walk Downtown/River | .5 mile SEMO

At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

Treehouse in Cape Girardeau

The custom-built treehouse is elevated on stilts, surrounded by greenery. A spacious deck features a railing, offering access to the entrance. Steps lead to the ground below, while large glass doors enhance the connection to nature.

4.99 out of 5 average rating, 141 reviews

Twisted Sassafras Treehouse

A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

4.87 out of 5 average rating, 102 reviews

A full laundry room is equipped with a washing machine and dryer, positioned side by side. Their modern design complements the space, offering convenience for guests. The area features a neutral color palette with wood accents, contributing to a clean and functional environment.

Home in Cape Girardeau

House Of Clubs- 2 Bed 1.5 Bath

The PERFECT hideway. The House of Clubs offers a quiet setting with a creek that wraps around the enitre property. Two bedrooms, each include a queen size bed. One Full bathroom. Full Laundry room that also offers a private cammode. The stylish living room offers a unique style that higlights Cape Girardeaus rich history. Enjoy your morning coffee in the four seasons room with breathtaking views of this hidden gem . Less than 5 minutes to downtown. Only 2 minutes to Cape Country Club.

4.96 out of 5 average rating, 195 reviews

A cozy outdoor fire pit area is surrounded by five blue Adirondack chairs, set against a vibrant sunset sky. Warm lighting hangs overhead, illuminating the spacious yard and providing a welcoming atmosphere for evening gatherings.

Barn in Cape Girardeau

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Guesthouse in Cape Girardeau

A wall featuring a combination of rough brick and stone textures is displayed. A clear parking sign stating 'GUEST HOUSE PARKING ONLY' is prominently positioned against the wall, ensuring visibility for guests utilizing the designated parking area.

4.94 out of 5 average rating, 514 reviews

Downtown Guesthouse- Romantic Getaway

The guesthouse seamlessly blends modern amenities with historic charm in a cozy, compact space. The antique claw foot tub/shower combo offers a charming, yet snug, spot for a relaxing soak—true to its historic roots, the bathroom could be best described as a quaint water closet. After a day of exploring unwind in the patio. Play a favorite record, and savor your coffee while daydreaming about new experiences. Despite its small size, it provides all the modern comforts you need.

4.77 out of 5 average rating, 100 reviews

A hallway is depicted, showcasing a doorway leading to a cozy bedroom. The walls are adorned with teal paint, while a decorative mirror and artwork frame the entrance. The wooden floor reflects natural light coming from a window at the far end.

Home in Cape Girardeau

Historic Blvd District Home in Cape Girardeau

This beautiful, private home is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. With large bedrooms, spacious living room and separate dining room you will have all the room you need! The kitchen is fully equipped with amenities. This quiet neighborhood setting with a big front porch sitting area where you can enjoy your morning coffee.

4.91 out of 5 average rating, 258 reviews

A spacious game room features a wooden pool table centrally positioned on a polished wooden floor. Soft green curtains adorn the windows, complementing the log cabin walls. In the corner, a dartboard is mounted, with a cozy seating area visible in the background.

Cabin in Cape Girardeau

Log Cabin w/ Hot tub - Near Casino & Downtown Cape

THE BEST GETAWAY HERE IN CAPE! Have a relaxing staycation here in Cape Girardeau Perfect for a QUICK GETAWAY for couples, families or friends 5 MINS to the casino, country club and downtown cape Very unique log home with a private bedroom queen size bed, pull-out queen size futon in the living room and twin size hide away SLEEPS 4. Pool table, darts, and a hot tub.There is a large deck and fire pit which has the feel of being in the woods.

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Popular amenities for Scott County vacation rentals

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Other great vacation rentals in Scott County

4.95 out of 5 average rating, 42 reviews

A spacious kitchen area features a large granite countertop with dual sinks. A cozy living space is visible, equipped with a dark sectional sofa. Natural light streams through large windows, illuminating the stone fireplace and dining area, which includes a wooden table and chandelier.

Cabin in Jackson

The Cabin at Timber Creek

StacyRating, 5 stars2 weeks ago

The property is beautiful. The home is exquisite. The only thing we would’ve like to have seen was recommendation for food in town. We’ll be back on our way to Mississippi! Absolutely lovely experience and the host was very friendly and responsive.

A private deck is highlighted, featuring a round glass table surrounded by six black metal chairs. The scenic view includes the Mississippi River and a colorful sunset, with the silhouette of the Emerson bridge visible in the background.

4.95 out of 5 average rating, 42 reviews

Downtown Condo on the River

GrahamRating, 5 stars3 months ago

Michael's place in Cape G is a perfect place to stay while you visit. It's a block from the main drag with plenty of food and bars (check out the record lounge around the corner). There's a garage space, and the balcony on the top floor has views of the Mississippi. The apartment is clean and comfortable, it would be a good medium or long term stay if desired. The bed is comfortable, and the kitchen and bathroom are modern. We'd stay again if visiting.

4.85 out of 5 average rating, 26 reviews

A patio area features four outdoor chairs arranged around a small table, with a firepit made of stone nearby. Lush greenery surrounds the space, offering a view of the expansive countryside. A large tree provides shade, enhancing the outdoor setting.

Home in Advance

Willow Acres- 2BD/2BA w/ BBQ and outdoor patio

LoraRating, 5 stars3 weeks ago

CLEAN. Beautiful. Plenty of room. Exactly what we needed. 7 minutes from the grocery store. Very private. We happened to be there when the fireflies were very active. We were surrounded! It was magical!

4.98 out of 5 average rating, 48 reviews

A modern bathroom is equipped with a sleek glass shower enclosure featuring multiple shower heads and controls. A contemporary toilet is positioned beside the shower, and a plush mat is placed on the floor. Soft green walls complement the overall design.

Apartment in Marble Hill

Lovely 2 bedroom apartment with luxury shower.

nickRating, 5 stars2 weeks ago

we always have a good time at Mr Kirby's place it's always clean and they're always really nice to us

5 out of 5 average rating, 40 reviews

An outdoor seating area is situated under a wooden pergola, featuring comfortable wicker furniture arranged around a coffee table. The scene is complemented by a sunset view, with soft colors reflecting off the shared pool and surrounding greenery.

Guesthouse in Jackson

Guesthouse w/ pool, outdoor fireplace, game room

AllisonRating, 5 stars2 weeks ago

I was looking for a place with a beautiful pool to spend my birthday and found the perfect spot! The guest house was exactly as described and perfect for a day of lounging poolside. Very peaceful and private. The cinnamon rolls were delicious, too!

The kitchen features wood cabinetry and a decorative light fixture, casting a warm glow. A window with patterned valance allows natural light to illuminate the space. A small table with two high-backed chairs and a fruit bowl offers a cozy dining area. The floor is covered with patterned tiles.

4.91 out of 5 average rating, 11 reviews

Colorful Home in Cape

ChadleyRating, 5 stars3 weeks ago

Stayed in the wood room. Clean, very spacious, comfortable, etc. Would stay again. Rodney was available and proactive with communication. Located very close to downtown.

5 out of 5 average rating, 70 reviews

Dome in Cobden

The Dome At Blueberry Hill

DougRating, 5 starstoday

A Weekend in the Dome Tucked away in a quiet valley beneath a canopy of trees, the geodesic dome stood like a pearl in nature’s palm. For one perfect weekend, it was ours. From the moment we arrived, the world outside dissolved. Inside, the curved walls echoed laughter and the crackling of a fire. Light filtered through the triangular windows, painting the wooden floor with soft patterns as the sun moved. There was no Wi-Fi. No buzz. Just quiet—real quiet. We woke to the sounds of birds chirping and the curious glance of a chipmunk just outside. Raccoons raided the birdfeeder each night. A hawk soared above, catching thermals in lazy circles while woodpeckers knocked out their morse code. Sara had her coffee each morning like a ritual and sat outside to take in nature’s wealth. I watched her for a bit, smiled, then joined her. At night, the dome glowed softly under a galaxy of stars. We slept like babes. What an amazing place. Look forward to the next time.