Vacation rentals in Santo Tomas, Ponce

4.92 out of 5 average rating, 119 reviews

A round dining table with a glass top is surrounded by four chairs featuring yellow cushions. The setting is enhanced by a garden backdrop with colorful flowers and various plants. A terracotta pot stands nearby, adding to the outdoor ambiance.

Guesthouse in Ponce

The*Cottage, Adorable 1-BR,with romantic patio.

One room serves as full-service kitchen, with central island with stools for dining. Aso has an area with sofa and end table which serves as a small living room and entrance foyer. There is a separate bedroom, and a separate full bath beyond it. Centrally-located with easy access to all that Ponce has to offer. Car needed. Shared laundry. Romantic yard with soft lighting, plants & fruit trees. Parking on the street, safe, most neighbors also park there. Early check-in can sometimes be arranged.

4.98 out of 5 average rating, 165 reviews

A charming cabin crafted from natural materials is positioned atop a wooden structure. A thatched roof provides shade, while large glass doors invite light. A pool is visible in the foreground, reflecting the blue sky and surrounding greenery.

Cabin in Isabela

Casa Lola PR

In Casa Lola, nature is the protagonist of a hidden spot surrounded by mountains in Isabela. Unique views and a perfect place to disconnect and reconnect with your couple…. Come and enjoy our beautiful cabin on top of the mountain, completely private and experience the best nature environment. Fully equipped kitchen, indoor and outdoor showers, loft room with amazing sunrise and sunset views, infinity pool, sun chairs and relaxing hammock. A place that invites you to come again…..just enjoy.

A cozy sleeping area features a spacious bed dressed in dark bedding, with several decorative pillows arranged neatly. A large wall-mounted television is positioned above a sleek white media console. Natural light enters through sheer curtains, enhancing the relaxing ambiance.

4.87 out of 5 average rating, 143 reviews

Villa Secret-Lovely rental unit with free parking

Hey, Take it easy at this unique and tranquil getaway. Secret spot apartment with independent entrance giving you the relaxing time you need. Very cozy place super near to the tourist areas in a very secure neighborhood. Near to downtown Ponce, biggest mall in the south of the island, La Guancha, Castillo Serralles, Cruceta del Vigia, Ponce Yacht Club, Museums, Universities, Ponce Port and Casinos. No keys are required to get a great experience. Doors have a keyless code for your convenience.

Superhost

A modern living area features a light gray sofa with decorative pillows, accompanied by two bar stools at a sleek kitchen island. Round mirrors and minimalist decor enhance the space, while the open layout reveals a kitchenette area with contemporary finishes.

Condo in Ponce

4.81 out of 5 average rating, 144 reviews

Golden Nights a Centric Condo in Ponce w/ Parking

Enjoy a stylish experience at this centrally-located apartment. This is a recently remodeled 1 bedroom Apartment in Torre de Oro with Private Parking and gated access. We are just steps from the Ponce Art Museum, Ponce Food Truck Spot, Universities and many other restaurants and attractions. We also have a sofa-bed in the living area to fit groups of up to 4 people. The apartment has a kitchenette area (no stove) with microwave and a small fridge. We also have a washer and dryer.

A spacious room features two full beds with light-colored bedding and decorative pillows. An air conditioning unit is mounted on the wall, and a full-length mirror reflects the soft lighting. A seating area with a stylish chair is visible near large windows draped with light gray curtains.

4.98 out of 5 average rating, 277 reviews

Relax, Work & Enjoy: Solar-Powered and Pool Stay

Discover a comfortable and welcoming space perfect for immediate family of 4 looking to experience the best of Ponce. Group of friends are Not accepted. Our property is located near Plaza del Caribe Mall, Ponce Health Sciences, local hospitals, and the lively Convention Center. Dive into Ponce’s rich history with visits to landmarks like Castillo Serrallés, Parque de Bombas, and Plaza Las Delicias. For entertainment, the Ponce Hilton Golf & Casino and Hard Rock Café are nearby.

Superhost

A straw hat with a circular design hangs on the wall, featuring the text ‘PUERTO RICO’ and an illustration of a fish. In the background, a spacious bed is partially visible, complemented by soft, neutral-toned decor.

Guesthouse in Ponce

4.86 out of 5 average rating, 154 reviews

Ponce Coastal Cottage

Perfect cozy coastal cottage be it if it's for singles, career individuals and couples seeking a place to come relax during their stay in Ponce. Less than 1 min walk to the "bahia" where you can enjoy the breeze of the Caribbean Ocean, visit nearby cafés, restaurants or simply enjoy chatting with the locals in the Plaza 65 Infantería. Located perfectly less than 10 minutes from Hilton Casino & Golf Club, Walmart, Plaza del Caribe Mall, Centro del Sur Mall and much more.

A minimalist apartment layout features a cozy seating area with a blue sofa positioned near a side table and lamp. A light wooden dining table with two red chairs is visible, alongside a bed with a soft gray plush blanket. Natural light enters through the door leading to an outdoor space.

4.97 out of 5 average rating, 95 reviews

The Suites at Ponce #2

Enjoy a modern and stylish experience at this centrally-located apartment. Just a 10-minute walk to downtown Ponce so you can enjoy all the major tourist's attractions our town has to offer. Come, relax, and unwind in this minimalist apartment and disconnect a little from the outside world. Just a few minutes away from all the important landmarks (downtown, malls, hospitals, restaurants) and every major highway, which will take you to anywhere you want in Ponce.

The entrance to the en suite is highlighted by a green metal gate, opening to a pathway bordered by small plants. The structure features a modern, minimalist design with a clean white exterior and large windows that allow natural light to enter.

4.93 out of 5 average rating, 142 reviews

Full Equip 2BR + Secure Parking

Recharge in your cozy en suite (500sqft/46sqm) in the southern capital. This modern minimalist residence is located in a safe, convenient and central neighborhood in the geographic center of the city. Look for green quakers, butterflies, or our neighborhood colorful roosters. This immaculate en suite is set off by itself and has two comfortable queen-size bed, sleeper sofa, a modern kitchen and a spacious modern bathroom with beautiful exposed concrete.

A vibrant yellow exterior is showcased, featuring white window shutters and a modern glass door. A small outdoor seating area is presented with a compact table and two chairs, accompanied by potted plants that enhance the inviting atmosphere.

4.97 out of 5 average rating, 261 reviews

El Arca Guest House/ Moderno apartamento en Ponce

Un apartamento ideal para parejas con todas las comodidades, amueblado y decorado. Localizado en un ambiente tranquilo y seguro. Con la mejor ubicacion y accesibilidad a las siguientes areas: La Guancha, Hotel Caribe Hilton, Campo de Golf, Isla Caja de Muertos, Plaza del Caribe, Museo Arte de Ponce, Zona Historica, Cayo Cardona, El Paseo Lineal y a minutos de la Autopista PR52. Nuestro deseo es que nuestros huespedes tengan la mejor experiencia.

A private outdoor bathtub is surrounded by lush greenery, with tall plants creating a secluded atmosphere. Sunlight filters through the leaves, casting delicate shadows on the tub, which holds a gentle reflection of the scenery. A single tropical flower floats on the water's surface.

4.96 out of 5 average rating, 482 reviews

Secret Garden w/ Outdoor Bathtub and King Size Bed

Charming studio apartment with a magical private outdoor bathtub. Independent entrance from the main house. Very private. Full kitchen , spacious indoor bathroom. The apartment is newly renovated. Quiet residential neighborhood centrally located close to Ponce Hilton and Casino, Ponce Beach, La Guancha, Universities, Hard Rock Cafe Ponce, museum and Ponce Nautico. Contactless self check in.

4.98 out of 5 average rating, 241 reviews

An aerial view of a spacious home surrounded by lush greenery. The pink-roofed structure features a central pool area, complete with lounge chairs. The property is set amidst tropical landscaping, enhancing the serene atmosphere of the location.

Home in Adjuntas

Secluded Coffee Farmhouse w/ Heated Pool & Chimney

Owned 100% by a local family from Adjuntas, PR—two women veterans and a former firefighter—Hacienda del Holandés is a mountain escape on a working coffee farm. Fall asleep to the Coquí, wake to birdsong, sip coffee with stunning views, relax in the heated pool, and end your day by the fire pit or chimney. Perfect for unwinding, exploring, and reconnecting. BOOK NOW!