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Vacation rentals in Santo Domingo

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
An outdoor area features a transparent bubble room containing a spacious bed, surrounded by lush greenery. A private hot tub is situated next to a lounge area with seating. Pathways lined with plants lead down to the setting, enhancing the serene environment.
Dome in Ponce
4.93 out of 5 average rating, 711 reviews

Bubble Puerto Rico

Tenemos otra Villa disponible con las mismas características - https://www.airbnb.com/h/bubblepuertoricoeternal ¡Experimenta por primera vez en PR quedarte en una habitación de burbuja! Bubble PR es una estancia ecológica, mágica, escondida en las montañas de Ponce, PR. A 18 minutos de la Ciudad, podrás sumergirte en una experiencia única, romántica, para parejas o viajeros solos, rodeada de naturaleza, abundante en flora, fauna y situados en la orilla de uno de los ríos mas abundante de Ponce

Top guest favorite
A charming cabin crafted from natural materials is positioned atop a wooden structure. A thatched roof provides shade, while large glass doors invite light. A pool is visible in the foreground, reflecting the blue sky and surrounding greenery.
Cabin in Isabela
4.99 out of 5 average rating, 203 reviews

Casa Lola PR

In Casa Lola, nature is the protagonist of a hidden spot surrounded by mountains in Isabela. Unique views and a perfect place to disconnect and reconnect with your couple…. Come and enjoy our beautiful cabin on top of the mountain, completely private and experience the best nature environment. Fully equipped kitchen, indoor and outdoor showers, loft room with amazing sunrise and sunset views, infinity pool, sun chairs and relaxing hammock. A place that invites you to come again…..just enjoy.

Guest favorite
An aerial view captures a wooden cabin surrounded by lush greenery, showcasing a private swimming pool and a winding pathway. Tropical plants and trees create a serene atmosphere, while the cabin features a modern roof and is set against a backdrop of mountains.
Cabin in Juan González
4.91 out of 5 average rating, 369 reviews

Cabaña Rancho del Gigante

Acerca de este espacio Bienvenidos a Rancho del Gigante un punto de encuentro entre la naturaleza y tú ser interno. Encontrarás una pequeña cabaña con impresionantes vistas de las montañas. Rancho del Gigante te invita a sumergirte en esta aventura romántica para aventureros, pareja o viajeros. A solo 30 min de Ponce una de las ciudades de Puerto Rico. ACCESO COMPLETAMENTE ARREGLADO Y PRIVADO. La cabaña no tiene casas alrededor, estará totalmente inmerso en una finca con portón privado.

Top guest favorite
A wooden sign hanging from a roof displays ‘A Craftsman’s Cabin’ with the text ‘Grateful for your visit’ below. Soft light bulbs are strung nearby, surrounded by lush greenery, creating a natural, welcoming entrance.
Cabin in Las Marías
4.96 out of 5 average rating, 118 reviews

Mountain Cabin-River Hopping Tour & Waterfalls

Rustic mountain cabin in Puerto Rico with direct river access and natural pools for swimming and relaxing. Hike the property, enjoy evenings by the fire pit, or rest in simple comfort. Sleeps 6 with king, queen, and glamping options. Eco touches include finca fruits, backup power, and water supply. Your host also offers guided river hopping tours, sound healing, and cranial-facial massage for an extra cost. Beaches are 1h15–1h30 away — the perfect base for rivers, mountains, and coast.

Top guest favorite
Home in Yauco
5 out of 5 average rating, 185 reviews

Welcome to the Hidden Corner!

Welcome to the Hidden Corner where you will feel right at home. It is a very safe and quiet neighborhood with parking. Relax in the backyard over looking the mountains. You will find restaurants and supermarkets minutes away, many popular beaches within 20-30 minute drive. Shopping Mall 3 minutes away, ATM machines, downtown souvenir shops and much more. You will also be able to enjoy Yauco's famous Yaucromatic, amazing street art located on Calle E Sanchez Lopez right down town.

Top guest favorite
A serene swimming hole is nestled among lush greenery, with clear water reflecting the surrounding foliage. Gentle cascades of a small waterfall are visible in the background, enhancing the tranquil atmosphere of the forest. Sunlight filters through the leaves, creating a soft glow.
Cottage in Peñuelas
4.98 out of 5 average rating, 218 reviews

Casa Kadam: Puerto Rico Rainforest Retreat

Like a treehouse nestled in the forest, this eco-cottage ( solar powered ) is perfect for unwinding, quiet reflection and communion with nature. Bathe in the pure, healing waters of Quebrada Lucia flowing through the farm ( private swimming !) "...sprinkled with perfume and spread with flowers..." This property is a living organic farm/retreat dedicated to regenerative farming, yoga/meditation and habitat regeneration as contributions to the healing of our society and planet.

Top guest favorite
A colorful hammock is suspended between two posts, inviting relaxation. The lush greenery and distant hills are visible in the background, with a soft orange glow from the sunset casting a warm light over the landscape.
Home in Peñuelas
4.98 out of 5 average rating, 111 reviews

Mountain Views near Ponce, Puerto Rico

Casa Sol is in the heart of Peñuelas. It's perfect for families of all ages, and business people alike. With high speed internet, take your Zoom calls and stream your favorite shows! We're centrally located from beaches and tourist attractions. You're 15-minutes away from Ponce, the second most visited city on the island. Known for it's rich history, museums and Plaza Las Delicias. Its old town features grand mansions built in the unique Ponce Creole architectural style.

Top guest favorite
The entrance to the en suite is highlighted by a green metal gate, opening to a pathway bordered by small plants. The structure features a modern, minimalist design with a clean white exterior and large windows that allow natural light to enter.
Apartment in Ponce
4.94 out of 5 average rating, 177 reviews

Full Equip 2BR + Secure Parking

Recharge in your cozy en suite (500sqft/46sqm) in the southern capital. This modern minimalist residence is located in a safe, convenient and central neighborhood in the geographic center of the city. Look for green quakers, butterflies, or our neighborhood colorful roosters. This immaculate en suite is set off by itself and has two comfortable queen-size bed, sleeper sofa, a modern kitchen and a spacious modern bathroom with beautiful exposed concrete.

Top guest favorite
A private outdoor bathtub is surrounded by lush greenery, with tall plants creating a secluded atmosphere. Sunlight filters through the leaves, casting delicate shadows on the tub, which holds a gentle reflection of the scenery. A single tropical flower floats on the water's surface.
Apartment in Ponce
4.96 out of 5 average rating, 516 reviews

Secret Garden w/ Outdoor Bathtub and King Size Bed

Charming studio apartment with a magical private outdoor bathtub. Independent entrance from the main house. Very private. Full kitchen , spacious indoor bathroom. The apartment is newly renovated. Quiet residential neighborhood centrally located close to Ponce Hilton and Casino, Ponce Beach, La Guancha, Universities, Hard Rock Cafe Ponce, museum and Ponce Nautico. Contactless self check in.

Top guest favorite
Cabin in Lares
5 out of 5 average rating, 113 reviews

Rocky Road Cabin

Relájate en esta escapada única y tranquila. Cabaña lujosa con acogedoras instalaciones privadas, rodeada de naturaleza y montañas en el pueblo de Lares. En Rocky Road Cabin, se brinda un entorno acogedor y sereno, ideal para disfrutar en pareja, ofreciendo descanso y tranquilidad. Esta Cabaña está equipada con todas las comodidades esenciales para garantizar una estancia placentera.

Top guest favorite
An aerial view of a spacious home surrounded by lush greenery. The pink-roofed structure features a central pool area, complete with lounge chairs. The property is set amidst tropical landscaping, enhancing the serene atmosphere of the location.
Home in Adjuntas
4.98 out of 5 average rating, 254 reviews

Secluded Coffee Farmhouse w/ Heated Pool & Chimney

Owned 100% by a local family from Adjuntas, PR—two women veterans and a former firefighter—Hacienda del Holandés is a mountain escape on a working coffee farm. Fall asleep to the Coquí, wake to birdsong, sip coffee with stunning views, relax in the heated pool, and end your day by the fire pit or chimney. Perfect for unwinding, exploring, and reconnecting. BOOK NOW!

Top guest favorite
A two-story house is surrounded by lush tropical greenery, featuring large windows. A private heated pool sits in the foreground, with steps leading to the entrance. Sun loungers and a small table with chairs are positioned beside the pool, creating a serene outdoor space.
Home in Jayuya
4.97 out of 5 average rating, 385 reviews

Monte Niebla, a piece of heaven in the mountains

***PRIVATE AND HEATED POOL*** Connect with nature in this alluring paradise. Green mountains, fauna and flora, privacy , peace & quietness will be your companions in this central region of PR. Jayuya is a town full of culture and beauty . A private HEATED pool will compliment the most relaxing getaway you have ever dream of. Just arrive & enjoy !

Popular amenities for Santo Domingo vacation rentals

  1. Airbnb
  2. Puerto Rico
  3. Peñuelas
  4. Santo Domingo