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Vacation rentals in Santo Domingo de Guzman

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santo Domingo de Guzman

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A modern living room is displayed, featuring a sleek wall-mounted TV with a decorative fireplace visual. Soft lighting highlights the textured wall behind. A spacious sofa and stylish chairs provide comfortable seating, while large windows allow natural light to enter the space.
Apartment in Julieta Morales
4.82 out of 5 average rating, 513 reviews

✔️ CITY CENTER | LUXURY 2-BEDR. APT. | GREAT VIEWS

✅ BEST downtown LOCATION ✅ PRIVATE balcony with lounge area + Stunning City Views ✅ Shared ROOFTOP Gym, BBQ & Lounge Area ✅ 3 SMART TVs with Amazon Fire 1000+ MOVIES & International TV CHANNELS ✅ High-speed WIFI ✅ FREE private indoor parking ✅ Washer and dryer IN UNIT ✅ 24/7 Reception ✅ Fully Equipped LUXURY kitchen ✅ QUEEN size beds ✅ XL Dining table with space for 8 guests ✅ Great SOUND system ✅ AC in the living room & bedrooms ✅ PRIVATE and QUIET ✅ Steps away from BLUE MALL, LA SIRENA & BRAVO

LocationValueHospitality

Top guest favorite
Place to stay in Ciudad Colonial
4.96 out of 5 average rating, 100 reviews

La Casa de Juanchy - Colonial Villa w/Private Pool

Stay in a stunning colonial home full of charm and character in the heart of Santo Domingo’s Zona Colonial. Beautifully decorated and thoughtfully equipped, this spacious home offers modern comforts like strong A/C, comfortable beds, fast Wi-Fi, a full kitchen, and inviting indoor and outdoor living spaces. Guests love the peaceful courtyard, refreshing plunge pool, and relaxing atmosphere — all just a short walk from restaurants, cafés, shops, historic landmarks, El Conde, and the Malecón.

FamilyValueSleep quality

Top guest favorite
A rooftop pool glistens under a sunny sky, offering views of the ocean and cityscape. The infinity edge of the pool enhances the seamless connection with the horizon. Wooden decking surrounds the pool, providing a spacious area for relaxation.
Condo in Esperilla
4.98 out of 5 average rating, 127 reviews

Rooftop Pool*High Floor*Fast WiFi*24/7 Electricity

GUEST PAYING (BOOKER) MUST BE PRESENT AT CHECK-IN Work Remote from 24/7 Secured Tower in Santo Domingo + 3 bedrooms with bathrooms, + half bath; 13th floor, quiet + Fast internet, 100Mbps+ for Zoom/Netflix, back-up power, UPS + Comfortable beds, washer/dryer, New Air Conditioners + ROOFTOP POOL, gym + Walk to restaurants, parks, LDS Temple, clinics, CIPLA + Adjustable office desk/chairs, monitors/keyboards + 24/7 on-site security, 1 covered parking - NO PARTIES/NO SMOKING/No Pets

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Top guest favorite
Apartment in Santo Domingo
5.0 out of 5 average rating, 12 reviews

NEW Western Apt | King Bed + Rooftop Pool

Inspired by the charm of Old Town Montana, this apartment blends the warmth of natural wood, earthy tones, and contemporary Western design to create a one-of-a-kind experience. Every space features natural finishes, leather accents, rustic textures, and warm lighting, capturing the essence of an exclusive mountain lodge with beautiful city views. When it's time to cool off, take a refreshing dip in the stunning rooftop pool. Please remember to read the house rules before booking.

LocationAccuracyCleanliness

Guest favorite
A modern living area is featured with a spacious sectional sofa, designed for comfort. A large TV is mounted on a sleek black wall, while floor-to-ceiling windows showcase a city skyline at sunset. Elegant lighting fixtures add a contemporary touch to the space.
Apartment in Ensanche Quiqueya
4.93 out of 5 average rating, 76 reviews

NEW! Luxury Stay in the Heart of Santo Domingo

Welcome to our luxurious modern apartment! Featuring sleek design, marble finishes, and floor-to-ceiling windows with stunning city views, this space offers comfort and style. Relax in the spacious living area with a large TV, enjoy meals in the elegant dining space, and unwind in a cozy, upscale atmosphere. Thoughtful details, contemporary lighting, and plush furnishings make this the perfect retreat for travelers seeking sophistication and relaxation. Your ideal getaway awaits!

LocationFamilyNearby

Superhost
A modern living area features a sleek television displaying a fireplace image. A comfortable sofa is positioned near a coffee table adorned with decorative items. Light-toned walls and neutral furnishings create an inviting ambiance. A dining area with stools and an open kitchen is visible in the background.
Apartment in Viejo Arroyo Hondo
4.88 out of 5 average rating, 179 reviews

Stunning City Center Condo, Gym, Pool, Great Views

Beautifull, upscale city center two-bedroom condo, very well appointed with all the essentials you need for short or long stays; fully stocked kitchen, fast Wi-Fi, full AC… Amazing social area with pool, Gym, lounge area and more… Located in the heart of Arroyo Hondo, near restaurants, supermarkets and shopping malls. This apartment is excellent for business travelers, couples or just for tourism to get to know the beautiful and exiting city of Santo Domingo.

FamilyValueComfort

Guest favorite
A modern living space is captured, featuring a light-colored sofa paired with two decorative wall art pieces. A tall indoor plant adds a touch of greenery, while natural light filters through sheer curtains. A dining table and chairs are arranged nearby, creating a welcoming atmosphere.
Condo in Santo Domingo
4.91 out of 5 average rating, 166 reviews

Luxury Designer Apartment 2BR Prime Santo Domingo

Experience luxury in this modern 2-bedroom apartment in Piantini, Santo Domingo’s most exclusive area. Surrounded by top restaurants, shopping centers, and entertainment, it's perfect for business travelers, couples, or families. Enjoy a spacious, stylish living space, a private balcony with city views, and access to a rooftop pool, gym, and lounge areas. The building offers 24/7 front desk staff for a seamless experience.

ValueFamilyView

Superhost
Apartment in Viejo Arroyo Hondo
4.83 out of 5 average rating, 144 reviews

Cozy central apartment

Exceptional apartment with all the luxury and comfort you are looking for, an extremely cozy space, with all the amenities offered by a modern tower that has a swimming pool overlooking the city, gym, children's area, lobby, free parking and a roof. And if that weren't enough, close to all the country's shopping malls, with restaurants and bars nearby. It is a safe environment that is in a privileged area of the country.

LocationValuePets

Guest favorite
A modern living area features a gray sofa paired with two yellow stools. Wooden coffee tables are arranged at the center, adorned with a green decorative piece and a geometric sculpture. Light curtains frame a bright yellow door, adding a pop of color to the space.
Condo in Santo Domingo
4.92 out of 5 average rating, 565 reviews

Apartment with Jacuzzi-Private Terrace-BBQ Grill

Cross the bridge and you'll have a quiet space by day and a spectacular view by night. It's beautiful in the morning and at night to see the moon from an open space. You'll be close to everything to manage your errands or just stay in the apartment and soak in the Jacuzzi whenever you want, read a good book, play casino or walk to the supermarket and buy meat for chance on the grill. Relax and live the experience.

ValueFamilyLayout

Top guest favorite
A stylish living room is presented featuring a comfortable white sofa adorned with orange and brown throw blankets. A round black coffee table is centered on a geometric area rug, with two textured dark green chairs nearby. Large windows allow natural light to brighten the space.
Apartment in Viejo Arroyo Hondo
4.94 out of 5 average rating, 222 reviews

Luxury Apartment Centrally

This luxurious apartment has the main amenities to have an unforgettable vacation. We have a minibar, a swimming pool with an infinite view, a spectacular balcony, located in the very center of the city, next to Galería 360, 3-5 minutes by vehicle depending on traffic from Agora Mall. NOTES. The day before the guest's arrival, you should send your IDs for adults of legal age. Via AIRBNB messaging.

LocationValueAmenities

Guest favorite
A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.
Home in Santo Domingo de Guzman
4.95 out of 5 average rating, 149 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

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Superhost
Apartment in Santo Domingo
4.84 out of 5 average rating, 104 reviews

Studio apartment on the 17th floor, No Parking

Beautiful studio apartment, with one bedroom, ideal for sharing as a couple, located on the 17th floor, with social areas and all the necessary services for an excellent stay. The apartment has central air and does not have parking in the tower. It is located in the exclusive sector of Serralles, in the central part of Santo Domingo DN.

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Popular amenities for Santo Domingo de Guzman vacation rentals