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Vacation rentals in Santo Domingo de Guzman

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santo Domingo de Guzman

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A modern living room is displayed, featuring a sleek wall-mounted TV with a decorative fireplace visual. Soft lighting highlights the textured wall behind. A spacious sofa and stylish chairs provide comfortable seating, while large windows allow natural light to enter the space.
Apartment in Julieta Morales
4.83 out of 5 average rating, 508 reviews

✔️ CITY CENTER | LUXURY 2-BEDR. APT. | GREAT VIEWS

✅ BEST downtown LOCATION ✅ PRIVATE balcony with lounge area + Stunning City Views ✅ Shared ROOFTOP Gym, BBQ & Lounge Area ✅ 3 SMART TVs with Amazon Fire 1000+ MOVIES & International TV CHANNELS ✅ High-speed WIFI ✅ FREE private indoor parking ✅ Washer and dryer IN UNIT ✅ 24/7 Reception ✅ Fully Equipped LUXURY kitchen ✅ QUEEN size beds ✅ XL Dining table with space for 8 guests ✅ Great SOUND system ✅ AC in the living room & bedrooms ✅ PRIVATE and QUIET ✅ Steps away from BLUE MALL, LA SIRENA & BRAVO

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Top guest favorite
A well-lit bedroom features a spacious bed with crisp white linens. A piece of wall art depicting surfboards adds a touch of color. Natural light enters through a window next to a small desk and chair, with a ceiling fan providing ventilation.
Apartment in Santo Domingo
4.96 out of 5 average rating, 515 reviews

Majestic Apt Studio in the Heart of Santo Domingo!

Majestic Apt located in the center of Santo Domingo 2-5 mins walk to main avenues and no more than 10 mins walk to train station with transfers available to all train routes, only 1 mile away from "El Malecon". There are plenty of entertainment options nearby including malls, bowling, restaurants, movie theaters, and parks. Free washer and dryer after 3 nights stay. This is a new apartment (built in 2016) to include private parking with remote electric gate and security cameras.

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Guest favorite
A private jacuzzi is positioned on the terrace, providing views of the city, mountains, and ocean. The space is surrounded by modern tile and glass walls, allowing for a bright and open atmosphere, while green accents add a touch of nature.
Apartment in Santo Domingo
4.93 out of 5 average rating, 163 reviews

Luxury penthouse with private Jacuzzi, gym, and pool

This 20th-21st floor penthouse has a beautiful ocean, mountain, and city view with a private Jacuzzi. Located in a central area minutes from the city's best restaurants. It is suitable for any public because it is minutes from a mall, banks, bars, supermarkets and Mirador Sur Park. It is finely decorated in order to make your stay comfortable and relaxing. The private terrace is the apartment's charm because you can admire the entire city, the sea, and the mountains.

LocationValueDecor

Guest favorite
A modern living area features a comfortable sofa and a wooden coffee table on wheels. Green accent wall adds depth to the space, which is elegantly lit by pendant lighting. The open layout connects to a dining area with a table and chairs, emphasizing a spacious design.
Loft in Santo Domingo
4.91 out of 5 average rating, 347 reviews

Loft: Nature in the center with private terrace

The modern design loft is located on the second floor of a French designer house with a separate entrance and private terrace minutes from Mirador Sur Park in a central, residential, and quiet area of Santo Domingo. With a harmonious fusion of urban and natural. Large windows that allow natural light to bathe the space, highlighting earthy tones and vibrant greens. The loft with its own terrace is a charming escape in the heart of the city.

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Top guest favorite
A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.
Home in Ciudad Colonial
5.0 out of 5 average rating, 60 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

LocationValueBreakfast

Guest favorite
Apartment in Viejo Arroyo Hondo
4.89 out of 5 average rating, 76 reviews

Comfortable Central Apartment

Modern and spacious accommodation in the heart of Santo Domingo. Enjoy a spectacular rooftop pool with a panoramic view of the city and feel at home thanks to its warm design. Located right in front of the Galería 360 shopping center, with shops, entertainment and a variety of restaurants within walking distance. Ideal for families, couples, or travelers looking for comfort, style, and a prime location. Everything is nearby!

ValueFamilyCleanliness

Guest favorite
A modern living space is captured, featuring a light-colored sofa paired with two decorative wall art pieces. A tall indoor plant adds a touch of greenery, while natural light filters through sheer curtains. A dining table and chairs are arranged nearby, creating a welcoming atmosphere.
Condo in Santo Domingo
4.91 out of 5 average rating, 162 reviews

Luxury Designer Apartment 2BR Prime Santo Domingo

Experience luxury in this modern 2-bedroom apartment in Piantini, Santo Domingo’s most exclusive area. Surrounded by top restaurants, shopping centers, and entertainment, it's perfect for business travelers, couples, or families. Enjoy a spacious, stylish living space, a private balcony with city views, and access to a rooftop pool, gym, and lounge areas. The building offers 24/7 front desk staff for a seamless experience.

ValueFamilySolo travel

Guest favorite
A modern living area features a gray sofa paired with two yellow stools. Wooden coffee tables are arranged at the center, adorned with a green decorative piece and a geometric sculpture. Light curtains frame a bright yellow door, adding a pop of color to the space.
Condo in Santo Domingo
4.92 out of 5 average rating, 553 reviews

Apartment with Jacuzzi-Private Terrace-BBQ Grill

Cross the bridge and you'll have a quiet space by day and a spectacular view by night. It's beautiful in the morning and at night to see the moon from an open space. You'll be close to everything to manage your errands or just stay in the apartment and soak in the Jacuzzi whenever you want, read a good book, play casino or walk to the supermarket and buy meat for chance on the grill. Relax and live the experience.

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Top guest favorite
A stylish living room is presented featuring a comfortable white sofa adorned with orange and brown throw blankets. A round black coffee table is centered on a geometric area rug, with two textured dark green chairs nearby. Large windows allow natural light to brighten the space.
Apartment in Viejo Arroyo Hondo
4.93 out of 5 average rating, 214 reviews

Luxury Apartment Centrally

This luxurious apartment has the main amenities to have an unforgettable vacation. We have a minibar, a swimming pool with an infinite view, a spectacular balcony, located in the very center of the city, next to Galería 360, 3-5 minutes by vehicle depending on traffic from Agora Mall. NOTES. The day before the guest's arrival, you should send your IDs for adults of legal age. Via AIRBNB messaging.

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Top guest favorite
Apartment in Santo Domingo
4.98 out of 5 average rating, 59 reviews

Modern Apartment with Rooftop Pool & Ocean Views

Enjoy a comfortable stay in this modern apartment in La Julia, one of Santo Domingo’s most convenient areas. Bright and well-designed, it features a cozy bedroom, full equipped kitchen, and inviting living space. Relax at the rooftop pool with ocean and city views. Located minutes from restaurants, supermarkets, and main avenues—perfect for short or extended stays.

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Guest favorite
Loft in Santo Domingo
4.96 out of 5 average rating, 213 reviews

Penthouse with private jacuzzi and terrace

Relax and enjoy this beautiful penthouse, a quiet and spectacular space, where you will have privacy, a Jacuzzi and terrace exclusively for the use of the guests of that apartment. An excellent view of the city from the 20th and 21st floors.

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Top guest favorite
Apartment in Santo Domingo
5.0 out of 5 average rating, 16 reviews

Luxury Apartment 2 H

Exceptional apartment in the city center, has all the amenities needed to have an excellent stay. It is located in the exclusive sector of Esperilla, close to everything. It has a social area and central air.

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