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Vacation rentals in Santo Domingo de Guzman

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santo Domingo de Guzman

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
An outdoor pool is depicted, bordered by a wooden deck and sun loungers. Large glass panels are visible in the background, framing a view of the skyline. Lush green plants adorn the edges, complementing the clear blue sky above.
Apartment in Piantini
4.92 out of 5 average rating, 170 reviews

The perfect Airbnb for you II

Enjoy a stylish experience at this centrally-located hotel-style accommodation. Excellent for business, family sharing, and getting to know the city. Located in Santo Domingo's Donwtown, just steps away from the country's most exclusive shopping plazas and most important business centers. In addition, the accommodation has excellent areas for meetings, enjoyment, and the relaxation atmosphere you deserve. Co-Working, huge pool, Jacuzzi's, Lounge bar, fully equipped gym and 2 lobbies.

Top guest favorite
A rooftop pool glistens under a sunny sky, offering views of the ocean and cityscape. The infinity edge of the pool enhances the seamless connection with the horizon. Wooden decking surrounds the pool, providing a spacious area for relaxation.
Condo in Esperilla
4.98 out of 5 average rating, 127 reviews

Rooftop Pool*High Floor*Fast WiFi*24/7 Electricity

GUEST PAYING (BOOKER) MUST BE PRESENT AT CHECK-IN Work Remote from 24/7 Secured Tower in Santo Domingo + 3 bedrooms with bathrooms, + half bath; 13th floor, quiet + Fast internet, 100Mbps+ for Zoom/Netflix, back-up power, UPS + Comfortable beds, washer/dryer, New Air Conditioners + ROOFTOP POOL, gym + Walk to restaurants, parks, LDS Temple, clinics, CIPLA + Adjustable office desk/chairs, monitors/keyboards + 24/7 on-site security, 1 covered parking - NO PARTIES/NO SMOKING/No Pets

Top guest favorite
Apartment in Santo Domingo
5.0 out of 5 average rating, 11 reviews

NEW Western Apt | King Bed + Rooftop Pool

Inspired by the charm of Old Town Montana, this apartment blends the warmth of natural wood, earthy tones, and contemporary Western design to create a one-of-a-kind experience. Every space features natural finishes, leather accents, rustic textures, and warm lighting, capturing the essence of an exclusive mountain lodge with beautiful city views. When it's time to cool off, take a refreshing dip in the stunning rooftop pool. Please remember to read the house rules before booking.

Guest favorite
A modern living area is featured with a spacious sectional sofa, designed for comfort. A large TV is mounted on a sleek black wall, while floor-to-ceiling windows showcase a city skyline at sunset. Elegant lighting fixtures add a contemporary touch to the space.
Apartment in Ensanche Quiqueya
4.93 out of 5 average rating, 76 reviews

NEW! Luxury Stay in the Heart of Santo Domingo

Welcome to our luxurious modern apartment! Featuring sleek design, marble finishes, and floor-to-ceiling windows with stunning city views, this space offers comfort and style. Relax in the spacious living area with a large TV, enjoy meals in the elegant dining space, and unwind in a cozy, upscale atmosphere. Thoughtful details, contemporary lighting, and plush furnishings make this the perfect retreat for travelers seeking sophistication and relaxation. Your ideal getaway awaits!

Guest favorite
A stylish living area features a plush sofa with accent pillows and a cozy armchair, set against a modern accent wall. Natural light floods in through large windows, offering views of the city. A decorative coffee table adds interest to the space.
Apartment in Julieta Morales
4.95 out of 5 average rating, 117 reviews

POOL & GYM | BEST Central Location | LUXE CONDO!

- BEST downtown LOCATION - 2 Shared "Picuzzi style" ROOFTOP Pools with Jacuzzi Jets, Gym & Lounge Area - LUXURIOUS One-BDR Apartment - High-speed internet - FREE private indoor parking - XL Smart TVs - Washer and Dryer - 24/7 Reception & Security - Fully Equipped LUXURY kitchen - Walk-in closet and LUXURY 1.5 bathrooms - LUXURY Modern Decoration - PRIVATE Balcony with Stunning Views - Close to Grocery Stores, Luxury Malls, Restaurants, Bars, Shops and Highlights

Superhost
A modern living area features a sleek television displaying a fireplace image. A comfortable sofa is positioned near a coffee table adorned with decorative items. Light-toned walls and neutral furnishings create an inviting ambiance. A dining area with stools and an open kitchen is visible in the background.
Apartment in Viejo Arroyo Hondo
4.88 out of 5 average rating, 179 reviews

Stunning City Center Condo, Gym, Pool, Great Views

Beautifull, upscale city center two-bedroom condo, very well appointed with all the essentials you need for short or long stays; fully stocked kitchen, fast Wi-Fi, full AC… Amazing social area with pool, Gym, lounge area and more… Located in the heart of Arroyo Hondo, near restaurants, supermarkets and shopping malls. This apartment is excellent for business travelers, couples or just for tourism to get to know the beautiful and exiting city of Santo Domingo.

Top guest favorite
A serene rooftop pool area is highlighted by soft illumination from overhead lights. The tranquil water reflects the dusky skyline, with wooden decking providing a warm contrast. Lush greenery is visible at the pool's edge, creating a peaceful escape in the urban setting.
Apartment in Ensanche Quiqueya
5.0 out of 5 average rating, 174 reviews

174 5-star reviews, pool/2 jacuzzis/gym

I invite you to immerse yourself in the charm and comfort of this cozy accommodation in the heart of Santo Domingo, steps from the main shopping malls and restaurants. Here you will enjoy a unique and memorable hosting experience. In addition, your safety is our priority, with 24/7 surveillance and staff in the lobby always available. As your Airbnb host, I am committed to making your visit unforgettable and full of amenities. Welcome to your home away from home!

Guest favorite
A modern living space is captured, featuring a light-colored sofa paired with two decorative wall art pieces. A tall indoor plant adds a touch of greenery, while natural light filters through sheer curtains. A dining table and chairs are arranged nearby, creating a welcoming atmosphere.
Condo in Santo Domingo
4.91 out of 5 average rating, 165 reviews

Luxury Designer Apartment 2BR Prime Santo Domingo

Experience luxury in this modern 2-bedroom apartment in Piantini, Santo Domingo’s most exclusive area. Surrounded by top restaurants, shopping centers, and entertainment, it's perfect for business travelers, couples, or families. Enjoy a spacious, stylish living space, a private balcony with city views, and access to a rooftop pool, gym, and lounge areas. The building offers 24/7 front desk staff for a seamless experience.

Guest favorite
Apartment in Viejo Arroyo Hondo
4.85 out of 5 average rating, 142 reviews

Cozy central apartment

Exceptional apartment with all the luxury and comfort you are looking for, an extremely cozy space, with all the amenities offered by a modern tower that has a swimming pool overlooking the city, gym, children's area, lobby, free parking and a roof. And if that weren't enough, close to all the country's shopping malls, with restaurants and bars nearby. It is a safe environment that is in a privileged area of the country.

Top guest favorite
A stylish living room is presented featuring a comfortable white sofa adorned with orange and brown throw blankets. A round black coffee table is centered on a geometric area rug, with two textured dark green chairs nearby. Large windows allow natural light to brighten the space.
Apartment in Viejo Arroyo Hondo
4.94 out of 5 average rating, 222 reviews

Luxury Apartment Centrally

This luxurious apartment has the main amenities to have an unforgettable vacation. We have a minibar, a swimming pool with an infinite view, a spectacular balcony, located in the very center of the city, next to Galería 360, 3-5 minutes by vehicle depending on traffic from Agora Mall. NOTES. The day before the guest's arrival, you should send your IDs for adults of legal age. Via AIRBNB messaging.

Guest favorite
A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.
Home in Santo Domingo de Guzman
4.95 out of 5 average rating, 149 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Superhost
Apartment in Santo Domingo
4.84 out of 5 average rating, 104 reviews

Studio apartment on the 17th floor, No Parking

Beautiful studio apartment, with one bedroom, ideal for sharing as a couple, located on the 17th floor, with social areas and all the necessary services for an excellent stay. The apartment has central air and does not have parking in the tower. It is located in the exclusive sector of Serralles, in the central part of Santo Domingo DN.

Popular amenities for Santo Domingo de Guzman vacation rentals