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Vacation rentals in Santo Domingo de Guzman

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santo Domingo de Guzman

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Place to stay in Ciudad Colonial
4.96 out of 5 average rating, 100 reviews

La Casa de Juanchy - Colonial Villa w/Private Pool

Stay in a stunning colonial home full of charm and character in the heart of Santo Domingo’s Zona Colonial. Beautifully decorated and thoughtfully equipped, this spacious home offers modern comforts like strong A/C, comfortable beds, fast Wi-Fi, a full kitchen, and inviting indoor and outdoor living spaces. Guests love the peaceful courtyard, refreshing plunge pool, and relaxing atmosphere — all just a short walk from restaurants, cafés, shops, historic landmarks, El Conde, and the Malecón.

Guest favorite
A stylish living area features a plush sofa with accent pillows and a cozy armchair, set against a modern accent wall. Natural light floods in through large windows, offering views of the city. A decorative coffee table adds interest to the space.
Apartment in Julieta Morales
4.95 out of 5 average rating, 118 reviews

POOL & GYM | BEST Central Location | LUXE CONDO!

- BEST downtown LOCATION - 2 Shared "Picuzzi style" ROOFTOP Pools with Jacuzzi Jets, Gym & Lounge Area - LUXURIOUS One-BDR Apartment - High-speed internet - FREE private indoor parking - XL Smart TVs - Washer and Dryer - 24/7 Reception & Security - Fully Equipped LUXURY kitchen - Walk-in closet and LUXURY 1.5 bathrooms - LUXURY Modern Decoration - PRIVATE Balcony with Stunning Views - Close to Grocery Stores, Luxury Malls, Restaurants, Bars, Shops and Highlights

Superhost
A modern living area features a sleek television displaying a fireplace image. A comfortable sofa is positioned near a coffee table adorned with decorative items. Light-toned walls and neutral furnishings create an inviting ambiance. A dining area with stools and an open kitchen is visible in the background.
Apartment in Viejo Arroyo Hondo
4.88 out of 5 average rating, 180 reviews

Stunning City Center Condo, Gym, Pool, Great Views

Beautifull, upscale city center two-bedroom condo, very well appointed with all the essentials you need for short or long stays; fully stocked kitchen, fast Wi-Fi, full AC… Amazing social area with pool, Gym, lounge area and more… Located in the heart of Arroyo Hondo, near restaurants, supermarkets and shopping malls. This apartment is excellent for business travelers, couples or just for tourism to get to know the beautiful and exiting city of Santo Domingo.

Top guest favorite
A serene rooftop pool area is highlighted by soft illumination from overhead lights. The tranquil water reflects the dusky skyline, with wooden decking providing a warm contrast. Lush greenery is visible at the pool's edge, creating a peaceful escape in the urban setting.
Apartment in Ensanche Quiqueya
5.0 out of 5 average rating, 174 reviews

174 5-star reviews, pool/2 jacuzzis/gym

I invite you to immerse yourself in the charm and comfort of this cozy accommodation in the heart of Santo Domingo, steps from the main shopping malls and restaurants. Here you will enjoy a unique and memorable hosting experience. In addition, your safety is our priority, with 24/7 surveillance and staff in the lobby always available. As your Airbnb host, I am committed to making your visit unforgettable and full of amenities. Welcome to your home away from home!

Top guest favorite
Apartment in Santo Domingo
4.96 out of 5 average rating, 95 reviews

Walk to Agora Mall—Exclusive Condo w/Rooftop Pool

Stay in one of Piantini’s most sought-after apartments — a modern luxury space with rooftop pool and stunning panoramic city views. Enjoy a full gym, play area, and private parking with 24/7 security. Walk to Blue Mall, Ágora, and Galería 360, surrounded by top restaurants, cafés, and cinemas. Ideal for business or leisure guests seeking comfort, convenience, and style. Includes fast Wi-Fi and Smart TV with Netflix, Disney+, and Prime Video.

Guest favorite
A modern living space is captured, featuring a light-colored sofa paired with two decorative wall art pieces. A tall indoor plant adds a touch of greenery, while natural light filters through sheer curtains. A dining table and chairs are arranged nearby, creating a welcoming atmosphere.
Condo in Santo Domingo
4.91 out of 5 average rating, 168 reviews

Luxury Designer Apartment 2BR Prime Santo Domingo

Experience luxury in this modern 2-bedroom apartment in Piantini, Santo Domingo’s most exclusive area. Surrounded by top restaurants, shopping centers, and entertainment, it's perfect for business travelers, couples, or families. Enjoy a spacious, stylish living space, a private balcony with city views, and access to a rooftop pool, gym, and lounge areas. The building offers 24/7 front desk staff for a seamless experience.

Superhost
Apartment in Viejo Arroyo Hondo
4.83 out of 5 average rating, 145 reviews

Cozy central apartment

Exceptional apartment with all the luxury and comfort you are looking for, an extremely cozy space, with all the amenities offered by a modern tower that has a swimming pool overlooking the city, gym, children's area, lobby, free parking and a roof. And if that weren't enough, close to all the country's shopping malls, with restaurants and bars nearby. It is a safe environment that is in a privileged area of the country.

Top guest favorite
A stylish living room is presented featuring a comfortable white sofa adorned with orange and brown throw blankets. A round black coffee table is centered on a geometric area rug, with two textured dark green chairs nearby. Large windows allow natural light to brighten the space.
Apartment in Viejo Arroyo Hondo
4.94 out of 5 average rating, 224 reviews

Luxury Apartment Centrally

This luxurious apartment has the main amenities to have an unforgettable vacation. We have a minibar, a swimming pool with an infinite view, a spectacular balcony, located in the very center of the city, next to Galería 360, 3-5 minutes by vehicle depending on traffic from Agora Mall. NOTES. The day before the guest's arrival, you should send your IDs for adults of legal age. Via AIRBNB messaging.

Guest favorite
An expansive infinity pool is featured on the rooftop, offering panoramic views of the city skyline. Surrounding greenery in decorative planters enhances the space, while the clear blue water reflects the sky.
Apartment in Santo Domingo
4.89 out of 5 average rating, 173 reviews

Luxury Piantini/Pool/Gym/Rooftop/Balcony/BBQ/Wifi

Central apartment in the heart of Ensanche Piantini, close to the best restaurants, supermarkets, pharmacies, just steps from shopping centers. Super quiet, safe and exclusive area!! You will have a great experience with our gym, Infinity pool and wonderful rooftop terrace with ocean views and 360 views of the entire city of Santo Domingo. You'll love it!

Guest favorite
A modern living area features two armchairs in rose color opposite a sleek marble coffee table. A television is mounted on the wall, and light filters through sheer curtains, illuminating the space. Decorative elements include a vase of flowers on the side table.
Home in Santo Domingo de Guzman
4.95 out of 5 average rating, 150 reviews

Cozy & Beautiful City Center House with Jacuzzi

The House is located in " El Cacique", one of the safest areas in the city, with access to Malecón ( Caribbean Sea), supermarket and clinics 5 minutes walk, access to Mirador Sur park, and 15-20 minutes from the most prestigious shopping centers in the city. Located approximately 40 minutes from the airport and 14 minutes from Zona Colonial.

Superhost
Apartment in Santo Domingo
4.84 out of 5 average rating, 105 reviews

Studio apartment on the 17th floor, No Parking

Beautiful studio apartment, with one bedroom, ideal for sharing as a couple, located on the 17th floor, with social areas and all the necessary services for an excellent stay. The apartment has central air and does not have parking in the tower. It is located in the exclusive sector of Serralles, in the central part of Santo Domingo DN.

Superhost
A bright living area features floor-to-ceiling windows that allow natural light to fill the room. A modern gray sofa with teal accent pillows is positioned around a sleek glass coffee table, enhancing the contemporary feel. Light-colored marble flooring adds a touch of elegance.
Apartment in Santo Domingo
4.8 out of 5 average rating, 461 reviews

Modern Apartment in the City Center

Your family will be close to everything if you stay here! Very central and easily accessible accommodation in Naco. Your family will be close to everything when you stay here! Very central and easily accessible accommodation in Naco.

Popular amenities for Santo Domingo de Guzman vacation rentals