House vacation rentals in Santa Maria

Find and book unique houses on Airbnb

Top-rated house rentals in Santa Maria

Guests agree: these houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Home in Lompoc

4.95 out of 5 average rating, 128 reviews

Calle Del Flor🌼-Central Coast Wine Country Getaway

Welcome to Calle Del Flor in Lompoc, the City of Arts and Flowers! Come relax in this newly renovated and thoughtfully designed modern 3BD/2BA abode. Proximity to Solvang & Santa Ynez. This charming small town is home to Central Coast's best wineries and breathtaking mountain scenery. Looking for a weekend getaway to enjoy some wine in the Central Coast? This is the perfect spot for the distinctive wine connoisseur! Remote workers can look forward to fast WiFi, comfortable and cozy workspaces.

Jun 12 – 19

G$102,482 GYD per night

Guest favorite

Home in Oceano

4.88 out of 5 average rating, 414 reviews

Shore To Please Beach House Oceano Pismo Avila SLO

A complete downstairs beach house with a kitchen, living room, relaxing bedroom, smart TVs, backyard, BBQ, bikes & a game room- Unlimited Vehicle Pass to Dunes - 1 mile to beach - 3/4 mile to Enormous kids park - Restaurants within walking distance - Netflix - Boll & Branch bedding - 5-8 minute drive to Pismo, Grover Beach, & Arroyo Grande - Near Avila beach, Shell beach & San Luis Obispo - 20 min drive to Cayucos & Morro Bay. Visit our website DropMyPin. c om for complete amenities & pictures.

May 28 – Jun 4

G$33,435 GYD per night

Guest favorite

Home in Los Osos

4.95 out of 5 average rating, 332 reviews

Baywood Park Garden Cottage

Cosy and cute, private one bedroom tiny cottage in Baywood Park. Just minutes to Morro Bay or explore the ocean bluffs, bay and hiking trails in Montana de Oro State Park. The tiny house cottage resides in a sunny semi-rural residential neighborhood, just minutes to the bay and Elfin Forest. Comfy queen size bed in the separate one bedroom, large shower, full kitchen and dining area, private deck to watch the sunrise or sunset. Perfect for a short stay or to finally finish that novel :)

Aug 25 – Sep 1

G$29,516 GYD per night

Guest favorite

Home in Santa Maria

4.93 out of 5 average rating, 313 reviews

Beautiful Home, Central Coast

Beautiful spacious 4 bedroom, 3 bath home w/garage. Downstairs a newly remodeled kitchen with all new cabinets, stainless appliances, wine fridge, formal living and dining room and 1/2 bath ( no shower). Upstairs all 4 bedrooms w/ ceiling fans, 2 full baths and laundry room. Large lot w/ beautiful landscaped backyard w/ 2 patio tables and gas bbq. Located between San Luis Obispo and Santa Barbara. Close to Pismo Beach, Avila Beach, hiking trails, Chumash Casino, golf courses & many wineries.

Dec 28 – Jan 4

G$58,477 GYD per night

Superhost

Home in Los Alamos

4.83 out of 5 average rating, 258 reviews

Bodega House

Welcome to Bodega House! We can't wait to host you at our charming 1920s farmhouse in Los Alamos. Enjoy the chef's kitchen, private patio, and two cozy bedrooms while soaking up Santa Ynez Valley wine country. Our wine and beer garden, Bodega, is also on the property and features a retail shop, bocce ball, and a greenhouse filled with unique plants and pottery. Check it out and relax by the fire pit with a glass of wine during Bodega's business hours. Bodega is open Thursday - Sunday, 12-7 pm.

Jun 25 – Jul 2

G$88,191 GYD per night

Guest favorite

Home in Los Alamos

5.0 out of 5 average rating, 112 reviews

Centennial House - Old West meets Modern Farmhouse

Ideally located in the heart of Los Alamos, Centennial House is perfect for your next getaway. Explore artisanal dining, wine tasting, and antiquing adventures a short walk away, or relax on the expansive, adobe style front porch with a glass of Grenache made by one of our local female winemakers in hand. Enjoy the fine dining, hip happenings of Bell’s across the street and say howdy to the local caballeros riding down the road. Experience Santa Barbara Wine Country like never before!

Feb 28 – Mar 7

G$147,323 GYD per night

Guest favorite

Home in Arroyo Grande

4.88 out of 5 average rating, 454 reviews

( Sanitized!) Country home w/ backyard tiki hut

Note: We are thoroughly sanitizing every surface, handle, door knob, remote etc. for your safety during these uncertain times! As 10-time Superhosts we welcome you! This adorable home is perfect for couples or families. Enjoy the relaxation of country living; yet just 15 mins from the beaches. We have included everything we could think of for you to have a stress-free and fun vacation; the softest of beds & linens, a fully-stocked kitchen, games, fire-pit , cable tv and beach gear.

Oct 2 – 9

G$35,053 GYD per night

Guest favorite

Home in Baywood-Los Osos

4.95 out of 5 average rating, 125 reviews

Bright 1 bedroom on Morro Bay with 2 work stations

Work remote and enjoy the peaceful backbay lifestyle! Hear the sound of ocean waves from bed while you look up at the stars. Wander the waterfront walking paths at the end of the block. 5 minute drive to Montana de Oro State Park hiking and mountain biking. 15 minute drive to Morro Bay surfing or San Luis Obispo shopping. 2nd floor unit with large deck and lots of natural light. 2 full work stations including standing desk that can be set up in the bedroom or living room.

Sep 7 – 14

G$38,070 GYD per night

Guest favorite

Home in Orcutt

4.96 out of 5 average rating, 142 reviews

Lux 2 bd, W/D, Patio, 20 min VSFB, Wineries, Beach

Kick back & relax in this calm, modern space. Enjoy the privacy of your own home with contactless check-in, high speed internet, comfortable beds, pull-out memory foam sofa sleeper for added guests, full kitchen just waiting for your culinary desires, and a patio with dining set for 6 Santa Maria is located near many wineries, hiking/mountain biking trails and we're only 20 minutes to the beach. Enjoy being centrally located while you explore the beautiful central coast.

Dec 10 – 17

G$50,174 GYD per night

Guest favorite

Home in Atascadero

4.99 out of 5 average rating, 243 reviews

The Luxury Retreat at Serendipity Farms - Dogs OK

This special place high up on the hills with views of the oak valley below. 15-20 minutes to Paso Robles Wine Country. House is filled with all the luxury amenities you'll have the pleasure to enjoy. With lots of wildlife deer, hawks, owls & wild turkeys. Beautiful & peaceful ranch feeling . 3 miles from highway 101 for fast traveling but yet you'll feel as if your out in the quiet country without any city lights or noise.

Sep 29 – Oct 6

G$38,613 GYD per night

Guest favorite

Home in Lompoc

4.98 out of 5 average rating, 240 reviews

Gorgeous Log Home on Working Ranch + Farm

Situated on a working ranch, this log home has a large master bedroom, 2 add'l bedrooms upstairs, gourmet kitchen & expansive outdoor areas for lounging, hiking, bbq'g & playing - all in the heart of Santa Ynez Valley wine country. Feed our friendly goats, chickens, horse and sheep while you're here. Hike the trails of the ranch and don't forget to visit world-class beaches nearby!

Jan 31 – Feb 7

G$164,569 GYD per night

Guest favorite

Home in Grover Beach

4.85 out of 5 average rating, 169 reviews

2 Bed 1 Bath "Sandcastle Coastal Cottage"

Please read through the whole description before messaging with questions! Come explore the hidden gem known as Grover Beach in this adorable loft! Equipped with a fully stocked kitchen, amazing little living space, outdoor deck with grill and seating, washer, dryer, and garage, this unit is perfect for a couple or family wanting to visit the beach!

Jan 11 – 18

G$31,440 GYD per night