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Vacation rentals in Santa Isabel

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Isabel

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A modern single-story home is presented with a minimalist design. The exterior features columns in a vibrant red and a pathway lined with stone tiles leading to the entrance. Landscaping includes neatly arranged plants in decorative pots, enhancing the inviting surface.
Home in Santa Isabel
4.8 out of 5 average rating, 139 reviews

Rancho Luna Suite jacuzzi. Near beach & hot spring

Kick back and relax in this modern and stylish space with jacuzzi, near thermal hot springs, rivers and best beaches. Hacienda Doña Elba, Coamo hot springs, Aventura 4x4, Caribbean Cinemas, Velódromo de Coamo, Maratón San Blas, Salinas, Juana Diaz, Rest El Platanar, La Parrila 153, Isabelle Rest, Bar O Bar, Ruta 153 Gastro Bar, Rest La Guitarra, Rest La Ceiba, Carnaval Rest., Playa Jauca, Malecón de Santa Isabel, Sunset Bar and Grill, Sea Angels Rest, Cabas Rest, El Rincon del Pescador and more.

Superhost
Cabin in Santa Isabel
4.83 out of 5 average rating, 18 reviews

Private Unique Cabin: Unmatched Comfort & Nature

Unplug at Bamboo Cabin, a rustic yet modern hideaway on a lush 160-acre ranch between Coamo and Santa Isabel. Wake to birdsong, breathe fresh country air, and stargaze under Puerto Rico’s skies. Perfect for couples, families, or friends, the cabin features two king bedrooms with balconies, a daybed for two, A/C throughout, a full bath, a spacious kitchen, and a terrace. Just a short drive from the coast, city, and mountains, it’s a serene escape surrounded by farms and nature.

Top guest favorite
A serene outdoor area features a swimming pool with a shallow end and colorful floating lights. Surrounding the pool, lush greenery and ornamental plants are present. Casual seating areas with patio chairs complement the inviting landscape, alongside a two-story structure that houses communal spaces.
Cabin in Santa Isabel
5 out of 5 average rating, 61 reviews

Pampagrass View, come and relax

Come and enjoy a different concept with beautiful panoramic views of the Caribbean Sea and the Mountains. On the first level there is a living room, kitchen and dining room, which is an open space. On the terrace in the evenings, you can enjoy the stars. Activities are allowed at an additional charge and must be coordinated in advance. It is important to obtain prior written approval. Unauthorized events are strictly prohibited. We will also charge an additional cleaning fee.

Top guest favorite
Shipping container in Santa Isabel
4.99 out of 5 average rating, 173 reviews

Dreamy

Vive la experiencia… ¡Apto sólo para SOÑADORES! Adéntrate a la naturaleza, en una localización accesible con una vista espectacular. Disfruta desde la única montaña que tiene el pueblo de Santa Isabel. Podrás disfrutar una estadía de ensueño, radiantes amaneceres, espectaculares atardeceres e iluminadas noches. En la distintiva y privilegiada vista, se perfila el mar Caribe, los cultivos agrícolas conjuntamente con los icónicos molinos de viento y abundantes montañas.

Guest favorite
A private deck features a sunken hot tub surrounded by wooden decking. A hanging chair adds a relaxed seating option. The area is enclosed by metal panels and greenery, with soft lighting provided by string lights overhead. A clear view of the water is visible beyond.
Shipping container in Jauca
4.94 out of 5 average rating, 410 reviews

Small Romantic space with a swimming pool and private dock

Be Happy offers you a unique ocean view towards Jauca Bay with pool and dock. "Todo lo que se ve en las fotos es para uso exclusivo de los dos huéspedes. No se comparte nada con otras personas ya que es el único alojamiento de la propiedad." "Be Happy offers you a unique sea view of Jauca Bay with a pool and dock. Everything you see in the photos is for the exclusive use of the two guests. Nothing is shared with others as this is the only accommodation on the property."

Guest favorite
Home in Santa Isabel
4.91 out of 5 average rating, 11 reviews

𝓛𝓸𝓸𝓸'𝓼 𝓗𝓸𝓾𝓬𝓮 beautiful modern house

Discover your home away from home in 𝓛𝓸𝓵𝓸'𝓼 𝓗𝓸𝓾𝓼𝓮. Imagine waking up with stunning views of the windmills, enjoying the tranquility, and exploring everything the area has to offer. Enjoy the pool & terrace in total privacy. A surprising distance from Prados Mall, Movie Theater, Starbucks, Fast Food. 2 minutes from Highway #52 and 3 minutes from Walmart. The Coamo Hot Springs are the only hot sulfur waters in PR just 15 minutes away

Guest favorite
A serene nighttime view of the rooftop accommodation illuminated by string lights. The pool reflects calming blue hues, surrounded by palm trees. A cozy outdoor seating area with a large umbrella complements the inviting atmosphere, while well-maintained greenery frames the space.
Shipping container in Playa
4.89 out of 5 average rating, 220 reviews

TAKE IN THE SUNSET FROM OUR LUXURY ROOFTOP ☀️🌅

Welcome to KAI Roof View in Santa Isabel, Puerto Rico! Discover paradise from above on our exclusive rooftop. Our accommodation is an oasis of relaxation and breathtaking sunsets. Just minutes from the beach and close to wonderful cuisine. 📸 Share your experiences using #KAIRoofView and join our networks. Your perfect getaway starts here!

Guest favorite
Apartment in Santa Isabel
4.88 out of 5 average rating, 139 reviews

Molinos House 2

This elegant space offers you everything you need to enjoy a pleasant experience on the beautiful coast of Puerto Rico. Located just 4 minutes from the famous Santa Isabel Pier, you'll be surrounded by the best beachfront restaurants, where you can savor exquisite local cuisine while enjoying breathtaking sunsets.

Guest favorite
A modern house exterior is viewed at night, showcasing a sleek entrance with large glass panels and a minimalist design. The driveway is visible, highlighted by soft lighting that emphasizes the building's clean lines and contemporary style. Windows are positioned symmetrically on the facade.
Home in El Ojo
4.78 out of 5 average rating, 37 reviews

Hidden House

Ubicación céntrica, a minutos de Walmart, del Mall, del malecón de Santa Isabel y a minutos de los baños de Coamo. Casa cómoda y placentera. Área pacífica, tranquila y acogedora. Excelente espacio para descansar y pasar la noche luego de un día de trabajo o un día de paseo por el área.

Superhost
A modern kitchen area is featured, complete with a refrigerator, microwave, and stove. White cabinetry complements the gray countertops. Two barstools are positioned at the counter. A television mounted on the wall displays the word 'DAYLIGHT,' and natural light flows through a window.
Home in Santa Isabel
4.84 out of 5 average rating, 146 reviews

Casa Del Sol-Modern Home in Puerto Rican Paradise

Cozy and modern 2-bedroom, 1-bathroom home on the southern part of the island. The home offers accommodations for 5 people, making it ideal for families or couples. Very close to many beaches and other sites you may find on the island.

Top guest favorite
Apartment in Santa Isabel
4.97 out of 5 average rating, 31 reviews

Comfy Apartment

Relax with the whole family at this peaceful place to stay. This apartment is minutes away from Santa Isabel Malecon and beaches, walking distance to Downtown and Restaurants. Peaceful and secure inside a controlled access area.

Top guest favorite
A serene outdoor space is highlighted by a refreshing swimming pool, seamlessly integrating with a wooden deck overlooking the ocean. Lush green plants border the area, creating a natural separation. Comfortable lounge chairs are positioned for relaxation while enjoying the tranquil sea views.
Home in Santa Isabel PR
5 out of 5 average rating, 47 reviews

Las Casitas Beach Retreat (Cabin #2)

An exclusive and private family space on the coast of Santa Isabel PR. Experience the unique experience offered by our space, with amazing sunsets and the relaxing sound of the waves of the Caribbean Sea.

Popular amenities for Santa Isabel vacation rentals