Vacation rentals in Santa Cruz
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Top-rated vacation rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz vacation rentals
Other great vacation rentals in Santa Cruz
Guest favorite
Vacation home in Puerto Ayora
4.96 out of 5 average rating, 54 reviewsBrand new apartment in the heart of Puerto Ayora
Dec 3 – 10
G$36,588 GYD per night
Guest favorite
Guest suite in Puerto Ayora
4.98 out of 5 average rating, 52 reviewsLinda suite en Puerto Ayora, Galápagos
Aug 23 – 30
G$11,498 GYD per night
Superhost
Guesthouse in Puerto Ayora- playa de los alemanes
4.82 out of 5 average rating, 51 reviewsGalapagos - Isla Santa Cruz -Janine's Chalet
Aug 30 – Sep 6
G$77,556 GYD per night
Guest favorite
Apartment in Puerto Ayora
4.95 out of 5 average rating, 59 reviewsDepartamento “Raya”
Jun 18 – 25
G$8,575 GYD per night
Guest favorite
Home in Puerto Ayora
4.97 out of 5 average rating, 35 reviewsShangri-La Legal Rental steps to the beach
Feb 22 – Mar 1
G$91,510 GYD per night
Guest favorite
Home in Puerto Ayora
4.88 out of 5 average rating, 34 reviewsDepartamento centro de Puerto Ayora
Aug 2 – 9
G$7,727 GYD per night
Guest favorite
Apartment in Puerto Ayora
4.89 out of 5 average rating, 28 reviewsEcolodge Tortuga Bay - excelente ubicación
Aug 20 – 27
G$11,026 GYD per night
Guest favorite
Home in Puerto Ayora
5.0 out of 5 average rating, 6 reviewsDepartamento amoblado Santa Cruz
Jun 1 – 8
G$7,507 GYD per night
Destinations to explore
- San Cristobal Vacation rentals
- Santa Cruz Island Vacation rentals
- Isabela Island Vacation rentals
- Puerto Ayora Vacation rentals
- Baltra Island Vacation rentals
- Puerto Villamil Vacation rentals
- San Cristóbal Island Vacation rentals
- Puerto Baquerizo Moreno Vacation rentals
- Playa de Oro Vacation rentals
- El cascajo Vacation rentals
- Playa los alemanes Vacation rentals
- Point Carola Beach Vacation rentals
- Yurt Rentals United States
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- Castle Rentals United States
- Houseboats United States
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- Cabin Rentals Australia
- Luxury Cabins United Kingdom
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- Holiday Chalets United Kingdom
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- Holiday Apartments Australia
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- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
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- Pet-Friendly Vacation Rentals United States
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- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom