
House vacation rentals in Santa Cruz
Find and book unique houses on Airbnb
Quick stats about house rentals in Santa Cruz

Total vacation rentals
Explore 60 vacation rentals in Santa Cruz

Verified guest reviews
Over 1,710 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
50 of Santa Cruz vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Cruz rentals

4.8 Average rating
Santa Cruz stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Santa Cruz
Guests agree: these houses are highly rated for location, cleanliness, and more.

Boutique House in Private Vineyard in Apalta
@boutiqueapalta Wake up surrounded by Chile's most renowned wine valley. This house combines contemporary design, nature and the unique experience of staying in an active vineyard. Designed by Teodoro Fernández, National Architecture Prize, it offers a perfect blend of rural and modern with an environment abundant in vegetation. 8 km from S. Cruz, you will be surrounded by the most prestigious vineyards in the country, a privileged environment that is difficult to find in another area of Chile.
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La Puerta Cabin
Escape to the heart of the Colchagua Valley Enjoy a comfortable and quiet stay in our cabin for 4 people, located just 7 minutes from downtown Santa Cruz. Ideal for those looking to disconnect, perfect for exploring local cuisine, visiting boutique vineyards and discovering everything the Colchagua Valley has to offer. The cabin is new and runs on sustainable energy. Its peaceful surroundings and proximity to outstanding restaurants will make your experience unforgettable.
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House on a private vineyard with panoramic views
Contemporary designer house on an exclusive private vineyard in the Apalta Valley. Accommodating up to 6 people, it offers spacious rooms, elegant décor, and floor-to-ceiling windows with spectacular views of vineyards and hills. A unique retreat to unwind in style, enjoy unforgettable sunsets, and have a premium experience in total privacy. Minutes from the main vineyards, such as Viña Montes, Clos de Apalta, and many more. Two minutes from the Fuegos de Apalta restaurant.
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Casa de Luz, fully equipped with parking.
Cozy retreat in the heart of the Colchagua Valley Discover a warm, bright space full of positive energy in Santa Cruz. A cozy equipped house, ideal for resting, reconnecting or enjoying the wonders of the valley: vineyards, history, gastronomy and nature. Here everything is designed to make you feel at home and that special touch that only a home with soul can offer. Wifi, full kitchen. Steps from the best vineyards Ideal for couples, families or solo getaways.
LocationFamilyCleanliness

ColchaguaFarm
Enjoy a couples getaway in the middle of vineyards with temperate pool Watch the stars next to a stove Sleep in a vineyard and enjoy the Chilean countryside Horseback Riding Bicycle tour Country breakfast products of the countryside Dive into your private pool looking at the vineyards Sharing with Horses Sheep Hens Make your asado in a private quincho in the middle of orange trees and vineyard view Enjoy the best of Colchagua Valley
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Casa Parrón
Have fun with the whole family in this stylish accommodation. Cozy house with an excellent location and ample parking Enjoy a comfortable and relaxing stay in this spacious house, ideal for families or groups of friends. It accommodates up to eight people. In addition, the house has ample parking and is in an excellent location, perfect for a quiet getaway or an extended stay. We look forward to seeing you!
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Just like home...
Two-story colonial-style house, tiles, wooden gate closure. Decorated mostly with Raulí furniture. Cozy atmosphere, quiet neighborhood, quiet, ideal for resting away from noise. Close to Colchagua Casino, museum, plaza, bars, pub and restaurants. Uber contact for a known and trusted person. The house has private parking for two vehicles. Air conditioning, Wi-Fi, Netflix, and terrace for grilling.
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Garden House
Cozy typical Chilean house, in the heart of Santa Cruz, inside the Viña Laura Hartwig. Large spaces, unique details and a vineyard environment. Ideal for enjoying the countryside with all the comforts and warmth. Perfect for those looking to experience nature, the charm of the Colchagua Wine Route and the Chilean countryside.
LocationFamilyCheckout

LODGE ACACIA CAVEN
Lodge Acacia Caven Un espacio de lleno de tranquilidad y confort ,conectado con la naturaleza, a 4 km del centro de de ciudad de Santa Cruz, ubicado en parcela de agrado privada. Casa de 100 metros cuadrados con Hot Tub externo, Terraza, Fogón, estacionamiento propio, zona para asado y entrada independiente.
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Sunsets in the Valley · Country House and Pool
In a house in the middle of a field of mandarins and avocados. It has panoramic views of the valley, which offer incredible sunsets. It has an en-suite room with views and the rest of the beds are in a cabin on site, in the common area. It is a house designed to be together and enjoy with family or friends.
LocationFamilyNearby

Casa Sta. Cruz Valle-Colchagua Vineyard: Estc. BBQ Area
Casa Viñastay is located in the Colchagua Valley and on the wine route, 500 meters from the casino, the Colchagua Museum and the center of Santa Cruz. Ideal for teleworking with fast Wi-Fi, air conditioning, and a wood-burning stove. Firewood is available for its operation.
ValueLocationNearby

Casa de Campo in Santa Cruz
Modern country house very close to Santa Cruz. 4 bedrooms, master bedroom en suite. Master and second bedroom with a double bed. In the second bedroom, the bed can be separated into two singles. Many walks and sights along the wine route. 5 kilometers from the square.
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Popular amenities for Santa Cruz house rentals
House rentals with a pool

Casa Santa Cruz, Colchagua Valley, Chomedague
LocationValueCondition

Malva House, Palmilla, Santa Cruz
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“El Descanso” family plot
LocationFamilyLaundry

Country house in the heart of the city
LocationValueCleanliness

Country house in Colchagua
LocationFamilyGrill

Country House - François Lurton
Indoor spacesOutdoor spacesBathroom

Casa El Huique
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Casas Santa Cruz 1
LocationFamilyAccess
Weekly house rentals

Cabin in Colchagua Valley
LocationValueHeating

Double room with twin beds and a private bathroom
LocationNearbyBreakfast

Your ideal retreat to disconnect in Santa Cruz
HospitalityIndoor spacesAccess

Family home, quiet place
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Cabin in Los Boldos, second floor
HospitalityIndoor spacesComfort

Comfortable and quiet house.
LocationFamilyHeating

Santa Cruz, Colchagua Valley
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Hostal del Vino (Wine Hostel) Master bedroom
LocationCleanlinessComfort
Private house rentals

comfortable house, large garden with pool.
ComfortIndoor spacesCleanliness

House near the center with a view of the field
LocationAccessBathroom

Palmilla country house.
LocationHospitality

House with a view, Colchagua Valley, Lolol
LocationOutdoor spacesNearby

Casa Cálida Colchagua

Accommodation in Santa Cruz
LocationFamilyHot tub

"Las Camelias" House in the Heart of San Vicente
LocationComfortIndoor spaces

Comfortable and cozy house
ComfortCheck-inHospitality
When is the best time to visit Santa Cruz?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$12,965 GYD | G$12,129 GYD | G$13,174 GYD | G$13,174 GYD | G$12,756 GYD | G$12,129 GYD | G$11,920 GYD | G$11,710 GYD | G$11,292 GYD | G$11,920 GYD | G$12,129 GYD | G$11,501 GYD |
| Avg. temp | 22°C | 21°C | 19°C | 14°C | 11°C | 9°C | 8°C | 10°C | 12°C | 14°C | 18°C | 20°C |
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