
House vacation rentals in Santa Cruz
Find and book unique houses on Airbnb
Quick stats about house rentals in Santa Cruz

Total vacation rentals
Explore 60 vacation rentals in Santa Cruz

Verified guest reviews
Over 1,710 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
50 of Santa Cruz vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Cruz rentals

4.8 Average rating
Santa Cruz stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Santa Cruz
Guests agree: these houses are highly rated for location, cleanliness, and more.

Boutique House in Private Vineyard in Apalta
@boutiqueapalta Wake up surrounded by Chile's most renowned wine valley. This house combines contemporary design, nature and the unique experience of staying in an active vineyard. Designed by Teodoro Fernández, National Architecture Prize, it offers a perfect blend of rural and modern with an environment abundant in vegetation. 8 km from S. Cruz, you will be surrounded by the most prestigious vineyards in the country, a privileged environment that is difficult to find in another area of Chile.
LocationFamilyKitchen

Lodge La Puerta
Escape to the heart of the Colchagua Valley Enjoy a comfortable and quiet stay in our cabin for 4 people, located just 7 minutes from downtown Santa Cruz. Ideal for those looking to disconnect, perfect for exploring local cuisine, visiting boutique vineyards and discovering everything the Colchagua Valley has to offer. The cabin is new and runs on sustainable energy. Its peaceful surroundings and proximity to outstanding restaurants will make your experience unforgettable.
LocationFamilyWifi

House on a private vineyard with panoramic views
Contemporary designer house on an exclusive private vineyard in the Apalta Valley. Accommodating up to 6 people, it offers spacious rooms, elegant décor, and floor-to-ceiling windows with spectacular views of vineyards and hills. A unique retreat to unwind in style, enjoy unforgettable sunsets, and have a premium experience in total privacy. Minutes from the main vineyards, such as Viña Montes, Clos de Apalta, and many more. Two minutes from the Fuegos de Apalta restaurant.
LocationFamilyCleanliness

Casa de Luz, fully equipped with parking.
Cozy retreat in the heart of the Colchagua Valley Discover a warm, bright space full of positive energy in Santa Cruz. A cozy equipped house, ideal for resting, reconnecting or enjoying the wonders of the valley: vineyards, history, gastronomy and nature. Here everything is designed to make you feel at home and that special touch that only a home with soul can offer. Wifi, full kitchen. Steps from the best vineyards Ideal for couples, families or solo getaways.
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Colchagua Farmstays
Sleep in a loft among Cabernet Sauvignon vineyards in the Colchagua Valley You will enjoy a breakfast included in the rate with products from the countryside. You can go horseback riding as a couple with a guide accompanying you You have bicycles to ride In the loft you have firewood to use the fireplace or an outdoor stove Enjoy a private quincho with a charcoal grill and a large table Enjoy with horses, sheep, chickens 24-hour check-in
LocationViewBiking

Casa Mimbre Santa Cruz
Cozy and comfortable house located in the heart of Santa Cruz, steps from the Casino, the Plaza and the Colchagua Museum. Enjoy the Colchagua Valley, its folklore, cuisine, and renowned wine culture. House decorated with wicker furniture, ample parking and self-sustaining with photovoltaic panels, for a more environmentally friendly stay. 🍷 Complimentary bottle of wine from the valley. 14% weekly discount and 30% monthly discount.
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Casa Parrón
Have fun with the whole family in this stylish accommodation. Cozy house with an excellent location and ample parking Enjoy a comfortable and relaxing stay in this spacious house, ideal for families or groups of friends. It accommodates up to eight people. In addition, the house has ample parking and is in an excellent location, perfect for a quiet getaway or an extended stay. We look forward to seeing you!
FamilyLocationAir conditioning

Casa Gonzalo
Two-story colonial-style house, tiles, wooden gate closure. Decorated mostly with Raulí furniture. Cozy atmosphere, quiet neighborhood, quiet, ideal for resting away from noise. Close to Colchagua Casino, museum, plaza, bars, pub and restaurants. Uber contact for a known and trusted person. The house has private parking for two vehicles. Air conditioning, Wi-Fi, Netflix, and terrace for grilling.
LocationValueHospitality

Garden House
Cozy typical Chilean house, in the heart of Santa Cruz, inside the Viña Laura Hartwig. Large spaces, unique details and a vineyard environment. Ideal for enjoying the countryside with all the comforts and warmth. Perfect for those looking to experience nature, the charm of the Colchagua Wine Route and the Chilean countryside.
FamilyLocationSleep quality

Sunsets in the Valley · Country House and Pool
In a house in the middle of a field of mandarins and avocados. It has panoramic views of the valley, which offer incredible sunsets. It has an en-suite room with views and the rest of the beds are in a cabin on site, in the common area. It is a house designed to be together and enjoy with family or friends.
FamilyLocationAir conditioning

LODGE ACACIA CAVEN
Lodge Acacia Caven A space full of tranquility and comfort ,connected with nature, 4 km from the city center of Santa Cruz, located on a private plot of pleasure. House of 100 square meters with external Hot Tub, Terrace, Stove, own parking, barbecue area and independent entrance.
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Casa Sta. Cruz Valle-Colchagua Vineyard: Estc. BBQ Area
Casa Viñastay is located in the Colchagua Valley and on the wine route, 500 meters from the casino, the Colchagua Museum and the center of Santa Cruz. Ideal for teleworking with fast Wi-Fi, air conditioning, and a wood-burning stove. Firewood is available for its operation.
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Popular amenities for Santa Cruz house rentals
House rentals with a pool

Casa Aromo
FamilyLocationNearby

Casa Malva, Palmilla, Santa Cruz
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Large house in Lago Rapel, Ohiggins Region.
FamilyAccuracyPool

Cozy cabin
FamilyLocationComfort

Country house in the heart of the city
ValueLocationIndoor spaces

Provençal-style house
FamilyLocationBackyard

Country House - François Lurton
Outdoor spacesIndoor spacesHospitality

Country house in Colchagua
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Weekly house rentals

Cozy house near wine yards
LocationFamilyComfort

Comfortable and quiet house.
ValueLocationWalkability

Hostal del Vino (Wine Hostel) Master bedroom
LocationIndoor spacesSleep quality

Cabin in Colchagua Valley
LocationFamilyKitchen

Micro Cabana, "Nido Estelar"
LocationValueAir conditioning

Santa Cruz, Colchagua Valley
FamilyLocationCondition

Cabin in Los Boldos, second floor
CleanlinessComfortIndoor spaces

Your ideal retreat to disconnect in Santa Cruz
ComfortAccessHospitality
Private house rentals

Family home, quiet place
LocationFamilyComfort

Double room with twin beds and a private bathroom
LocationNearbyHospitality

"Las Camelias" House in the Heart of San Vicente
LocationAmenitiesIndoor spaces

Cabin in Marchigue
LocationValueTV

“Cabin for 6 people” - Colchagua Camp lodge
LocationFamilyView

comfortable house, large garden with pool.
CleanlinessAccuracyComfort

House near the center with a view of the field
LocationComfortCheck-in

House with a view, Colchagua Valley, Lolol
LocationNearbyLayout
When is the best time to visit Santa Cruz?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$13,043 GYD | G$12,202 GYD | G$13,253 GYD | G$13,253 GYD | G$12,833 GYD | G$12,202 GYD | G$11,991 GYD | G$11,781 GYD | G$11,360 GYD | G$11,991 GYD | G$12,202 GYD | G$11,570 GYD |
| Avg. temp | 22°C | 21°C | 19°C | 14°C | 11°C | 9°C | 8°C | 10°C | 12°C | 14°C | 18°C | 20°C |
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