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Guesthouse vacation rentals in Santa Clarita

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Santa Clarita

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A comfortable living area features a blue sofa facing a flat screen TV on a wooden cabinet. Warm wooden beams highlight the ceiling, while a colorful area rug adds contrast to the light wooden floor. A large glass door opens to a view of greenery.
Guesthouse in Pasadena
4.97 out of 5 average rating, 454 reviews

Cozy Guesthouse Surrounded by Nature

Convene with nature while sitting on the tranquil deck of this secluded home close to Pasadena and downtown LA. The relaxing feel continues indoors, with high beamed ceilings, warm wooden floors, and colorful rugs. Furnishings are comfy and eclectic. For the convience of our guests, a crib is offered for a nominal fee. We offer a stand alone high speed internet connection dedicated just to the guesthouse. EV charging is available for the guest. The chargers are 240 volts level chargers We have a queen bed w/ a soft down comforter, a queen size sofa bed, a flat screen TV, modern appliances, and beautiful finishing touches from my family - such as fresh flowers! :) The guest house is 100 feet away from the main house. Guests will have plenty of space, their own modern kitchen, washing/drying machine, flat screen TV, a bathroom with a shower and plenty of parking right next to the guest house. My family is very friendly - we will be living across the lot at our house. Please feel free to chat with us - we've lived in LA a long time and are always happy to offer suggestions or advice. The neighborhood consists of houses built during the '50s and '60s, mostly ranch style houses with large lots. The house sits approximately 100 feet off the main street, at the end of the golf course. It is a very quiet neighborhood. Of course, you can park your car on our long driveway! The Gold Line is 2 miles south. It goes into LA downtown Union Station. From there are different subway or metro lines which go to Culver City, Santa Monica, Universal Studios, Long Beach There are hiking trails right outside the door. All guests staying more than a week get maid service every Friday. A baby cot/crib is available for guests who have a need for it at an addional cost of $25 per stay

Top guest favorite
A tranquil evening scene by the pool features illuminated water in shades of blue. A jacuzzi is situated nearby, while string lights create a warm ambiance overhead. Comfortable seating is arranged around the pool area, surrounded by lush greenery, providing a welcoming outdoor space.
Guesthouse in Newhall
4.98 out of 5 average rating, 499 reviews

Cozy Guesthouse with Private Pool + Heated Jacuzzi

✅ Prime Location: 12 min to Magic Mountain, 30 min to Universal Studios, 45 min to the beach. Close to dining and shopping. *Private guesthouse with its own entrance, fully fenced for your peace and privacy. *Relax with a private pool (not heated), a large heated spa, and a Blackstone griddle for outdoor cooking. *Master bedroom + open loft (as a second bedroom), kitchenette (no oven), living room, WiFi, washer/dryer. *Dedicated parking. Max 8 guests (contact us for exceptions). No parties.

Top guest favorite
A large private pool is surrounded by lush tropical plants and a spacious deck area. A shaded cabana offers a comfortable retreat nearby, with light filtering through the draped curtains, creating a refreshing outdoor environment.
Guesthouse in Reseda
4.98 out of 5 average rating, 725 reviews

Plant Lover's Paradise: Jacuzzi/Pool, 420 Welcome

Unwind in our studio guesthouse, tucked away in a peaceful backyard retreat with a large private pool, cabana, massage chair, and hot tub. Immerse yourself in paradise, surrounded by tropical fruit trees, an organic garden, and an aquaponics system. Outdoor bliss awaits for 420 enthusiasts (outdoors only). Mention '420 friendly' while booking to receive a gift of our homegrown, pesticide-free cannabis. Max 2 guests, no exceptions. Kindly review our description and house rules before booking.

Guest favorite
The exterior of a spacious, two-story house is shown, featuring a light-colored facade and a terracotta tile roof. A landscaped front yard includes shrubs and decorative stones. A driveway leads to a garage, and the surrounding neighborhood gives a sense of tranquility.
Guesthouse in Santa Clarita
4.87 out of 5 average rating, 217 reviews

HILLSIDE GETAWAY next to Magic Mountain

Great reviews beautiful quiet neighborhood on top of hill with an amazing view of the surrounding mountains w/private entrance 15min drive to six flags magic mountain bike paths an nature trails shopping and malls less than 5 min drive everything newly built all guests have given me 5star accommodations easily sleeps 4 people fold out couch in living room queen size bed in bedroom room 16 ft high cathedral ceiling private balcony /tables&chairs purfect to unwind 30 min from universal studios

Top guest favorite
A cozy studio interior showcases a queen bed adorned with decorative pillows and a soft throw. A futon is positioned nearby, with a small table between them. Natural light fills the space, highlighting the calming color palette and inviting decor, along with a glimpse of the kitchen area.
Guesthouse in Sylmar
4.97 out of 5 average rating, 231 reviews

Tranquil Studio w/ private patio

A beautiful and well maintained Tranquil Studio/ With a Private Patio. Entire Studio to yourselves. 2 guests. 1 queen bed..1 queen/futon couch, with lovely bed linens and plush towels. 1 tub/shower.Futon made up on request at the time of booking. Full kitchen with everything you’d need to make delicious meals. 55” TV/ DVDs Washer/dryer...please bring your own laundry soap and dryer sheets. The gorgeous private patio has plenty of space to relax and enjoy your meals, or just hang out.

Top guest favorite
An open studio guest house features a plush queen bed framed by bedside lamps and a ceiling fan. A cozy sofa and recliner are situated beside a small retro refrigerator and a coffee station. A neutral area rug enhances the warmth of the wood flooring.
Guesthouse in Newhall
5 out of 5 average rating, 143 reviews

Hideaway Heaven $120 per night + 25.00 cleaning

Where movie magic happens nestled in the heart of Santa Clarita is a charming studio guest house thoughtfully designed with all the comforts of your own home including a soak in tub to enjoy and relax after a long day. Location is key, and this beautiful guest home is minutes from the 14 freeway,hiking trails , dining, Six Flags Magic Mountain, and film locations. This attached suite is newly renovated with all new furnishings, a private and separate entrance with a designated parking spot.

Guest favorite
The guest room features a spacious queen bed with white linens, complemented by decorative pillows. A large area rug adds color to the hardwood floor. Natural light enters through double doors leading to a private patio, with sheer curtains softly framing the entrance.
Guesthouse in Reseda
4.94 out of 5 average rating, 596 reviews

Private Guesthouse

This is a very comfortable NON-SMOKING guesthouse/ studio room with private entrance. Absolutely NO ANIMALS allowed due to my allergies. It has one queen bed. Private full bathroom. There is dresser space as well as hangers. It also has a desk for work space. Smart TV can be used with streaming services. This space does not have a kitchen. But it does have a small fridge and a microwave. Absolutely no filming or photography anywhere on the premises. No visitors allowed without my consent.

Top guest favorite
A cozy guest room is equipped with a spacious bed covered in a textured blanket. A sleek work desk and chair are visible, along with a television displaying a beach scene. Large glass doors lead to an outdoor patio area, and a potted plant adds a touch of greenery.
Guesthouse in Burbank
4.98 out of 5 average rating, 315 reviews

Private Guest Quarters with Patio & Bathroom

Enjoy a stylish experience at this centrally-located place in Burbank. Walking distance to Starbucks, minutes away from Disney Studios, Warner Bros. and Universal Studios. Conveniently located near the Hollywood Burbank Airport. Perfect for one-guest. Host lives on premises. Room has a private entrance with outdoor patio. There are two cameras located on the property, one on the Hosts front door, the second one attached to the Hosts home overlooking the backYard.

Top guest favorite
The charming exterior of the casita is highlighted by its decorative arches and pastel-color façade. An outdoor patio area features several potted plants, a table with an umbrella, and stairs leading to the entrance. The space reflects a serene environment, surrounded by lush greenery.
Guesthouse in Hollywood Hills
4.96 out of 5 average rating, 754 reviews

Historic LA Oasis with outdoor courtyard

This is a private, detached casita, steps from the famed Hollywood Bowl. It sleeps up to 3 people max - 1 queen bed upstairs and twin couch that converts into single bed in first floor living room. The casita is 2-stories, 780 sq. ft with AC, full bath & kitchen, living room and outdoor patio area. This historic home dates back to the early 1900s and sits within a larger compound that consists of a main house that is occupied by your Hosts.

Top guest favorite
A green wooden exterior features a welcoming front door framed by two large windows. A small seating area includes a metal chair next to the entrance, and potted plants add a touch of greenery along the pathway leading up to the door.
Guesthouse in Lake Hughes
4.92 out of 5 average rating, 337 reviews

The Guesthouse at Hidden Acres

Beautiful, rustic, quiet country get-away. Just 90 minutes North of L.A. on the edge of Angeles National Forest. Perfect for an artist or writer's retreat. Private studio guesthouse on 17 acres. New mini split unit keeps the space comfortable year round. And the wood-burning stove is super cozy on cold nights. Includes fully stocked kitchen, sunken tub in bath, large writer's desk, and miles of hiking trails along the Pacific Crest Trail.

Guest favorite
A spacious bedroom includes a large bed with a light coverlet, complemented by natural light from two windows dressed with soft curtains. A small wooden table and a woven basket provide additional decor, while greenery adds a fresh touch to the inviting space.
Guesthouse in Simi Valley
4.95 out of 5 average rating, 109 reviews

Rustic Ranch Retreat: Guesthouse with Nature Views

Escape to the tranquility of our picturesque working ranch, where you can experience the rustic charm of farm life like never before. Welcome to our one-of-a-kind Airbnb. Ranch Getaway: Unplug and unwind in our cozy guesthouse, nestled amidst the rolling hills of our working ranch. Here, you'll find a true escape from the hustle and bustle of city life, while only being one mile from the freeway. Parties are not allowed at The Ranch.

Top guest favorite
A serene bedroom features a spacious bed adorned with lavender and white linens. Elegant bedside tables flank the bed, while floral decor adds a touch of softness. A piece of art depicting roses hangs on the wall, complementing the gentle purple tones.
Guesthouse in Santa Clarita
4.9 out of 5 average rating, 119 reviews

Luxury Studio Lavender

Nestled in the heart of Santa Clarita Valley, this home is a charming guest house. The entrance is private and separate with a parking space. Tastefully decorated and furnished with new amenities, this place is perfect for your getaway. Hosts have created stylish accommodation, perfect for solo travelers, couples and even small families. Come and stay and let us please you with our hospitality, cleanliness and attention to detail.

Popular amenities for Santa Clarita guesthouse rentals

Quick stats about guesthouse rentals in Santa Clarita

  • Total vacation rentals

    Explore 20 vacation rentals in Santa Clarita

  • Nightly prices starting at

    Santa Clarita vacation rentals start at G$14,639 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,440 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Santa Clarita vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Clarita rentals

  • 4.9 Average rating

    Santa Clarita stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    Santa Clarita's top spots, include Valencia Stadium 12, California Institute of the Arts, and Vista Valencia Golf Course

Destinations to explore