Guesthouse vacation rentals in Santa Clarita

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Santa Clarita

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Altadena

4.99 out of 5 average rating, 351 reviews

The Alta Den

Open double French doors to a beautiful garden outside a stylish apartment. Located on a quiet street lined by 100-year-old Deodar trees, the private space ideal for couples; features a crisp, sleek aesthetic with succulents and a cozy outdoor lounge. Open double French doors to a beautiful garden and enjoy your morning coffee as you prepare for the day OR light a fire and snuggle up on the undercover porch when it starts to cool down in the evening. Whether in town for a meeting in one of the surrounding areas or attending an event at the Rose Bowl, this home has everything you need to make your stay relaxing and enjoyable. This private 500 sq. ft. studio apartment is the perfect place for a weekend getaway. In addition to the living space, there is a kitchen (see appliances below), large walk in closet, undercover porch and outside fireplace. This space comfortably fits 3 people, if you are happy to use the Milliard memory foam tri-fold mattress. If needing to do washing, a coin laundromat is .3 miles away from our home. Kitchen Appliances: Stove, Microwave, Toaster, Kettle, French Press, Nespresso, Aeroccino Milk Frother, NutriBullet and Soma filtered water jug. Amenities… Hairdryer, wifi, flat screen, TV with Netflix and Directv Now, full length mirror Guest will have full access to the studio apartment, yard, porch and fireplace. I like to meet guests upon arrival to give access and a tour of the property, but sometimes this is not possible. My husband and I live in the main house and are available to offer any advice on local attractions. The den sits behind the main house In Altadena, a short drive from good coffee shops and restaurants. It's accessible enough to explore the many eclectic neighborhoods of LA. There are numerous neighborhood trails that are great for walking. Although public transportation is available, the closest bus and Gold Line stop are about 1-mile away. We highly recommend having a vehicle to drive, but if in doubt, Uber! There is a designated parking spot on our property for you, and there is plenty of street parking (no restrictions, no tickets)!

Guest favorite

Guesthouse in Castaic

4.9 out of 5 average rating, 181 reviews

Minutes to Six Flags & Castaic Lake! Private 🚪🛁🛏🍽

Newly built little TINY boho guest studio in a super gorgeous, quiet and safe neighborhood. You have a private entrance and side yard with bistro table. Kitchenette with full size refrigerator, sink, stove and barstools. Wardrobe closet with two snugly white robes and slippers. Large full private bathroom and a full range of motion tv with roku for movie night in bed. Every guest we’ve ever had said that this bed is the most comfortable bed they have ever had at any air bnb!!! Come stay with us!

Guest favorite

Guesthouse in Simi Valley

4.97 out of 5 average rating, 102 reviews

Adorable Studio With Private Entrance

Enjoy your stay in this cozy, Brand New Attached ADU with its own private entrance. Located in a Beautiful quiet neighborhood in Simi Valley with tons of Hiking Trails, Beautiful Parks, Shopping at the Simi Valley Town Center, and lots of Restaurants. This cozy unit is perfect for a weekend getaway or even a home away from home. The unit is to the left of the main house comes with its own Full Bathroom, Queen memory foam mattress, sitting area , 40" smart tv, dinning area, and a Full kitchen.

Guest favorite

Guesthouse in Canyon Country

4.88 out of 5 average rating, 183 reviews

HILLSIDE GETAWAY next to Magic Mountain

Great reviews beautiful quiet neighborhood on top of hill with an amazing view of the surrounding mountains w/private entrance 15min drive to six flags magic mountain bike paths an nature trails shopping and malls less than 5 min drive everything newly built all guests have given me 5star accommodations easily sleeps 4 people fold out couch in living room queen size bed in bedroom room 16 ft high cathedral ceiling private balcony /tables&chairs purfect to unwind 30 min from universal studios

Guest favorite

Guesthouse in Sylmar

4.98 out of 5 average rating, 175 reviews

Tranquil Studio w/ private patio

A beautiful and well maintained Tranquil Studio/ With a Private Patio. Entire Studio to yourselves. 2 guests. 1 queen bed..1 queen/futon couch, with lovely bed linens and plush towels. 1 tub/shower.Futon made up on request at the time of booking. Full kitchen with everything you’d need to make delicious meals. 55” TV/ DVDs Washer/dryer...please bring your own laundry soap and dryer sheets. The gorgeous private patio has plenty of space to relax and enjoy your meals, or just hang out.

Guest favorite

Guesthouse in Chatsworth

4.9 out of 5 average rating, 203 reviews

Comfortable Private Studio - near hiking

Come get away to a slower pace at our thoughtfully appointed studio in the beautiful hills of Lake Manor! When staying at our place you will be a short drive to West Hills, Canoga Park, Calabasas, Northridge, and more. We are in a quiet neighborhood in the "country." Our studio setup allows traveling workers and getaway seekers to find the work-life balance they need with: ✧Comfy work desk ✧ High-speed Wi-Fi ✧Close by fun hiking trails ✧Roku TV ✧Shared outdoor space ✧ parking - free

Guest favorite

Guesthouse in Newhall

4.98 out of 5 average rating, 442 reviews

Cozy Guesthouse w pool, firepit & heated jacuzzi

GUESTHOUSE W PRIVATE USE OF BBQ, POOL, SLIDE, FIRE PIT & HEATED SPA CLEANED TO CDC RECOMMENDATIONS COMPLETELY SEPARATE FROM MAIN HOUSE WITH FENCE NO LOUD PARTIES, NO LIVE MUSIC. For your safety AIRBNB is not allowing parties or events to be hosted. NO MORE THAN 10 PEOPLE ALLOWED AT ANY TIME. Contact us if you need an exception. Guesthouse w kitchenette (no oven) living room, master bedroom, open loft (as 2nd bedroom) Dedicated parking, TV, WIFI, washer/dryer and private entrance.

Guest favorite

Guesthouse in Santa Paula

4.94 out of 5 average rating, 217 reviews

Charming (tiny!) Casita on the Hill

A magical space in a Spanish courtyard with citrus trees perfect for unwinding and enjoying the beautiful weather. You’ll love the outdoor tub and shower. Check the reviews — it’s usually the highlight for our guests! (To note: there is NO indoor tub or shower. ) Recently upgraded WiFi makes it a great remote working option, too. *** Please be aware that Highway 150 between Santa Paula and Ojai is closed temporarily due to a landslide. Estimated reopening is May, 2024. ***

Guest favorite

Guesthouse in La Crescenta-Montrose

4.96 out of 5 average rating, 260 reviews

Mid Mod in the City close to DTLA and Universal

Natural light-filled Mid Mod studio close to shops and restaurants in Montrose. The kitchenette is fully stocked with dishes and utensils. Short drive to Pasadena, DTLA and Universal. Dine on a private patio or sit by the fire pit with other Airbnb guests. The space is completely renovated and combines Mid Century Modern design with today's amenities. There are 3 buildings on the property, one is another Airbnb and the front house is occupied by a full-time tenant.

Guest favorite

Guesthouse in Northridge

4.97 out of 5 average rating, 254 reviews

Backyard paradise near CSUN, Universal & 6 Flags

Smell the flowers, pomelo blossoms and macadamia trees outside your window. The neighborhood and backyard allows for quiet sleep and star gazing by the pool (Puffy brand queen mattress). Porter Ranch is close to the 118 & 405. Non-rush hour driving in minutes: 5 ~ CSUN 20 ~ Burbank Airport (30 LAX) 20 ~ Universal Studios 20 ~ Six Flags/Hurricane Harbor 20 ~ Getty Center 30 ~ Downtown LA/Dodger Stadium 45 ~ Disneyland 60 ~ Santa Barbara 3.5-4 hours Las Vegas

Guest favorite

Guesthouse in Monrovia

4.99 out of 5 average rating, 471 reviews

Charming Guest House in the foothills of Monrovia

Charming detached guest house nestled in the foothills of the San Gabriel Mountains in a peaceful Monrovia neighborhood. This property is minutes away from Old Town Monrovia and feels worlds away from the hustle and bustle of the city. It has everything you need including a private entrance, comfortable King-size bed, bathroom with shower, 4K Smart TV with cable and Netflix access, refrigerator, Kerug coffee maker, free internet access and Wi-Fi.

Guest favorite

Guesthouse in Santa Clarita

4.99 out of 5 average rating, 152 reviews

The Pines- a peaceful ranch guesthouse

Enjoy a rural getaway at this recently renovated guest house on a small ranch. Minutes from the 5 freeway, shopping, restaurants and conveniences, yet a world away in a quiet neighborhood with farm animals and open views. This is a great place for nature lovers, with lots of plants, birds and even seasonal frogs. We have an EV charger available. Please ask for details.