
Vacation rentals in San Isidro
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Top-rated vacation rentals in San Isidro
Guests agree: these stays are highly rated for location, cleanliness, and more.

QuintaTemazcalli, Temazcal residence, swimming pool, chimney
Quinta Temazcalli, beautiful adobe and xalnene residence, swimming pool (optional air conditioning $1,500.00 per day. Temazcal ($250.00/person), fireplace, barbecue (does not include charcoal), campfire ($200.00 firewood load), bread oven. The magic of its beautiful garden with fruit trees to enjoy according to season, fish pond and the well will make you fall in love with the place. -4 spacious rooms. -Kitchen, dining room, 2 living rooms -Two terraces with incredible views -Canteen Have an incredible healing experience
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Casa Lozada – Spacious and beautiful home in Apizaco
Enjoy a comfortable, spacious and cozy home in Santa Ursula that will make you feel at home. It has 3 bedrooms, 2.5 bathrooms, equipped kitchen, terrace and garage for 2 cars. Strategic location: 5 minutes from the high-performance sports center, 10 minutes from downtown Apizaco, 20 minutes from Tlaxcala capital, 30 minutes from Huamantla and 25 minutes from the industrial corridor With easy access to transportation, supermarkets and schools. Ideal for relaxing and sharing unforgettable moments with family or friends
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Val'Quirico "Auguri" Zócalo, 5-Bed Apartment
Beautiful apartment ideal for 8 and up to 10 people in the heart of Val'Quirico Zócalo, enjoy it as a couple, family or with friends; 2 bedrooms (Bedroom 1 with King Size and Sofa King, Bedroom 2 with 2 Double Beds, 2 full bathrooms and 2 terraces with wonderful views, 1 Double Sofa Bed in the living room, living room, kitchen and bar; the best location according to the guests and us, surrounded by restaurants and overlooking the zócalo and the Casa de los Abuelos (Construction protected by the INA), you will love it!
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Complete House with 2 Bedrooms, Garden and Barbecue
Enjoy a comfortable and pleasant stay in this house with functional design and good taste. Perfect for families, couples or travelers, our house has everything you need to feel at home; comfortable rooms and hot water 24/7. Whether you are coming for work, tourism or visiting, you will find comfort and tranquility. 3 minutes from Chedraui, FEMSA, UATX, 7 minutes from the Apizaco Center, 8 from the Regional Hospital, 12 minutes from Ciudad Judicial, 20 from CIX I, and 30 minutes from La Malinche.
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Beautiful house with a large garden
Less than two hours from Mexico City, spacious and cozy house very well lit with large garden, ideal for resting in a peaceful place, meeting and living with family or friends, appreciate the majesty of the Malinche, have breakfast or roast a meat outdoors, even play volleyball or basketball, or relax in the jacuzzi. Strategically located 20 minutes from downtown Tlaxcala and less than an hour from tourist attractions such as El Santuario de las Luciérnagas and Val'Quirico.
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5 minutes from the High-Performance Deportiva de Alto Rendimiento (High Performance Sports Complex)
Stay in this spacious and cozy house, ideal for you or your family, within a private, quiet and safe residential development in the heart of Apizaco. Central location for exploring iconic places: Huamantla, La Trinidad, La Malinche volcano, the Cacaxtla archaeological zone, the Santuario de las Luciérnagas, the Barca de la Fe and more! 5 minutes from the High Performance Sports City and the Bullring. 8 minutes from downtown Apizaco. “Book now and enjoy your stay”
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Midnight Oasis
A space carefully designed to provide you with comfort and privacy, we create a warm and cozy atmosphere where you can rest comfortably and enjoy a quiet stay. Our penthouse offers you a beautiful outdoor terrace, where you can relax and enjoy beautiful sunsets, immersing yourself in an intimate and exclusive atmosphere. At Midnight Oasis, attention to detail is our priority. We take care of the decor and atmosphere to make you feel at home.
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A complete and centrally located apartment
Excellent full apartment with privileged location in Apizaco Tlax. Ideal for short and long stays, located on the second floor of a building, in front of the only Soriana in the center, 5 minutes from the city's main park and with a fast route to the main roads. It has two full bedrooms, a full kitchen, a full bathroom and a living room with all amenities. Free street parking or a boarding service a block and a half away at no extra cost.
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Spectacular Ranch 5 minutes from Trinidad IMSS
Bring the whole family to this fantastic place, enjoy the tranquility of nature, without leaving aside the fun both outside and inside, with the bar, pool table or movie night! Relax at this ranch located in the municipality of Santa Cruz Tlaxcala. Enjoy the views from the hillside, walk around the property, or visit the La Trinidad Holiday Center. At night, immerse yourself in the incredible views of the galaxy in the open field.
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AMAZING "CASA CARMELA" in the center of Apizaco
THIS SPACE FOLLOWS AIRBNB'S ADVANCED CLEANING PROTOCOL. Cozy and wonderful 1-story house, located in downtown Apizaco. Excellent location a few blocks from restaurants, bars, convenience stores, cinema, among others. The house has excellent essential services (Internet, Netflix), as well as a garage (5.0 meters long) for a small or medium-sized sedan or SUV. We accept small or medium-sized pets; large pets with prior approval.
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Casa Azul Room 1
Explore the Magic of Apizaco Stay in the heart of the city, near the Basilica, markets and local flavors. A perfect spot to explore Tlaxcala, Huamantla , Tlaxco and their magical villages, with the comfort and warmth you deserve. There is paid parking one block away, with security cameras and surveillance for peace of mind. An excellent option for a practical, safe and well-located stay.
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Entire apartment with private parking
Enjoy a complete, comfortable and private apartment in Apizaco, Tlaxcala. Just 10 minutes from downtown and with easy access to the main roads. It has 2 suite-style bedrooms, each with a living room, TV and sofa bed; one with a queen bed and the other with a double bed. Equipped kitchen, dining room for 8 people, full bathroom and private parking for 1 vehicle.
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Popular amenities for San Isidro vacation rentals
Other great vacation rentals in San Isidro

Apartment in the heart of Apizaco with garage.
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Welcome to Casa Rubí: Your refuge in Apizaco
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A pretty and central house in Apizaco
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Nice cabin to disconnect, Malinche
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Nice house, price per month companies, we invoice
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Great Getaway/Parking/Check-in/
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Spacious apartment in Apizaco | Patio and parking
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casa mateo
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Destinations to explore
- Val'Quirico
- Cabanas Zacatlan
- Izta-Popo Zoquiapan National Park
- Africam Safari
- Catedral de Puebla
- Ciudad Universitaria Buap
- Estadio Puebla Cuauhtémoc
- Hacienda Panoaya
- El Cristo Golf And Country Club
- Acrópolis
- UPAEP
- Ex Hacienda de Chautla
- Explanada Puebla
- Estrella de Puebla
- Parque Ecológico
- Artist Quarter
- Cascada Tuliman
- Museo Amparo
- Zócalo
- Museo Internacional del Barroco
- Universidad Las Americas
- Zona Arqueológica
- Sonata Market
- Waterfall Quetzalapan





