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Vacation rentals in San Antonio

Find and book unique accommodations on Airbnb

Quick stats about vacation rentals in San Antonio

  • Total vacation rentals

    Explore 60 vacation rentals in San Antonio

  • Nightly prices starting at

    San Antonio vacation rentals start at G$4,183 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,880 verified reviews to help you choose

  • Family-friendly vacation rentals

    30 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    50 of San Antonio vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Antonio rentals

  • 4.8 Average rating

    San Antonio stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated vacation rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Santo Domingo
4.98 out of 5 average rating, 55 reviews

Casa calentita con muebles nuevos

Acogedora casa en Santo Domingo, ideal para relajarse en un amplio terreno con patio de pasto, jardín con flores y terraza techada con parrilla. El living cuenta con chimenea de doble combustión, y la cocina recién remodelada incluye lavadora, secadora y lavavajillas nuevos. Las camas son nuevas con sábanas blancas de 400 hilos y los camarotes son firmes y de excelente calidad. Estacionamiento cerrado para 3 autos y Smart TV con más de 500 canales (Pluto TV). ¡Perfecta para tu escapada familiar!

Guest favorite
A serene view of the Rio Maipo is framed by lush greenery. Various trees and vibrant plants are visible, creating a natural boundary. The calm water reflects the surrounding landscape, inviting tranquil moments in nature.
Cottage in San Antonio
4.85 out of 5 average rating, 66 reviews

Maipo River House

Casa Familia Estilo Rustico diseñada por sus dueños, con muebles y decoraciones únicas al costado del Rio Maipo en San Antonio. Solo a una hora en auto de Santiago y Valparaiso. Cuenta con diferentes jardines, bella flora y fauna del lugar. Terraza con vista al río ideal para tomar desayuno y observar aves tanto nativas como migratorias en estaciones mas cálidas ideal para reencontrarse con la naturaleza y desligarse del día a día de la cuidad. Ideal para personas que les gusta la naturaleza

Top guest favorite
Cabin in Santo Domingo
5.0 out of 5 average rating, 28 reviews

Tiny House Santo Domingo, Casa Quintral

Escápate a una acogedora Tiny House inserta en la naturaleza, ubicada a sólo 8 minutos del Parque Tricao. Disfruta un merecido descanso con Hot Tub eléctrico, Quincho con parrilla, en un entorno rodeado de flora y fauna nativa. Ubicada en en un condominio cerrado, ofreciendo tranquilidad y seguridad, y a sólo 10 minutos de la playa de Santo Domingo. Ideal para parejas o pequeñas familias que buscan desconectarse del ritmo diario y reconectar con la naturaleza en un ambiente cómodo y acogedor.

Guest favorite
A vibrant sunset paints the sky with shades of orange and red, reflecting over the calm ocean waters. Silhouetted trees line the foreground, creating a serene natural scene that showcases the beauty of the coastal landscape.
Cabin in San Antonio
4.94 out of 5 average rating, 162 reviews

Cabaña Los Poetas

Cabaña full equipada de un ambiente, totalmente equipada, con cama matrimonial, futón, tv cable, AA (frío/calor), terraza con vista al mar, quincho y estacionamiento, ideal para 2 personas. A 10 minutos en auto de playas y a 5 minutos de casino, centro de San Antonio y punto de embarque a los cruceros en el puerto. La cabaña se encuentra ubicada en un ambiente de naturaleza, tranquilidad y seguridad ideal para el descanso en el litoral de los poetas cerca de museos. Por mascotas $15.000.-

Top guest favorite
Home in Santo Domingo
4.95 out of 5 average rating, 133 reviews

Santo Domingo, V Region, Vista espectacular

Casa del año 2018 y recién remodelada, luminosa, de concepto moderno, cómoda. Espectacular vista al mar y protegida del viento (250/700 m2), con piscina. Nivel principal: gran living comedor, cocina integrada y terraza, 1 dormitorio, 1 baño (piso 2). Primer piso: quincho interno y externo, sala estar, 1 dormitorio, 1 baño, lavadero); 3 piso (3 dormitorios y 2 baños). Calefacción central (cobro aparte). La piscina con arboles y follaje, puede tener algunas hojas. Estacionamiento 3 autos.

Guest favorite
A spacious outdoor living area is shaded by a wooden pergola, featuring comfortable wicker seating that faces the ocean. A built-in barbecue is positioned nearby, complemented by coastal views of the rocky shoreline and clear blue skies.
Home in El Quisco
4.9 out of 5 average rating, 161 reviews

Hermosa casa con quincho y terraza frente al mar

Prepárate para unos días con la mejor vista al mar, un sueño reponedor y para momentos inolvidables. Nuestra casa está en primera línea de playa, con quincho y terraza frente al mar y chimenea para los días fríos. Ubicada en un sector tranquilo y apartado, a pie de Supermercados y Restaurantes. Full equipada y muy cómoda, con todo lo necesario para tu estadía. Para acceder a la casa hay que subir una escalera desde el estacionamiento, no apta para personas con movilidad reducida.

Guest favorite
A bright living area features a large window offering expansive views of the ocean. A comfortable rattan chair sits beside a simple coffee table, while a white couch adds contrast. Soft lighting from floor lamps enhances the serene ambiance of the space.
Home in Isla Negra
4.93 out of 5 average rating, 134 reviews

Casa cómoda, vista al mar en tranquilo condominio.

Casa de vacaciones en tranquilo condominio privado. Lugar seguro con control de acceso. Gran antejardín y estacionamiento. Living comedor, cocina completamente equipada ( refrigerador, microondas, horno). Habitación principal con 2 camas de 1,5 plazas , y segunda habitación con 2 camas de 1 plaza. Amplia terraza con vista panorámica al mar. Baño equipado Internet Starlink Atracciones: - Casa de Pablo Neruda : 5 min. - Playa Punta de Tralca : 8 min. - Playa Algarrobo : 18 min.

Superhost
Apartment in San Antonio
4.83 out of 5 average rating, 30 reviews

Hermoso departamento con vista al mar - puerto

Departamento totalmente equipado, ubicado en sector céntrico, con hermosa vista al puerto. Cuenta con terraza cerrada, ideal para disfrutar increibles atardeceres durante todo el año. Excelente conectividad a comercio, restaurantes y servicios. A solo 15 minutos de Santo Domingo y de las playas de la costa como El Tabo, El Quisco e Isla Negra. Ideal para descanso, paseos familiares o viajes por trabajo. Incluye estacionamiento al interior del condominio.

Guest favorite
A warm living area features a brown leather sofa paired with a natural fiber rug. Plants are arranged on the coffee table and shelf, enhancing the space. Light filters in through large windows, providing a bright ambiance to the cozy setting.
Condo in San Antonio
4.95 out of 5 average rating, 302 reviews

Hermoso departamento en condominio

Disfruta de la sencilles de este alojamiento tranquilo y céntrico. Ideal para relajarse a 3 minutos del centro de San antonio cerca de playas.....estas 20 minutos del parque tricao !25 minutos de las brisas del mar!! 25 de la casa de pablo neruda!! nuestro gran poeta chileno premio nobel de literatura!!!!!!muchos otros lugares bellos de nuestro litoral central!! y a pasos de un nuevo mirador de nuestro puerto de san antonio !! es bellisimoooi!!!!

Guest favorite
A bright dining area features a wooden table surrounded by light-colored chairs. Large glass doors offer expansive views of the outdoor pool and surrounding landscape. A colorful wall art piece adds a touch of interest, with a woven light fixture hanging above the table.
Home in Tunquen
4.93 out of 5 average rating, 73 reviews

Moderna casa en Tunquén, con amplia vista al mar.

Desconecta de tus preocupaciones en este espacio amplio y sereno. Disfruta de bellos atardeceres desde cada una de las habitaciones, o caminando cinco minutos a la playa Las Conchitas. También puedes disfrutar de la piscina con borde infinito y vista al mar o descansar en una de las terrazas, una de ellas techada y otra en el segundo piso. La arquitectura permite la unión de los espacios o también la privacidad para momentos más íntimos.

Guest favorite
Cabin in Cartagena
4.9 out of 5 average rating, 62 reviews

Moderna Cabaña en Cartagena Con Jacuzzi opcional

Disfruta de una experiencia con estilo en este alojamiento céntrico y cómodo. A tan solo 5 min en vehículo del centro de Cartagena y de la playa. Como así a 30 min del parque Tricao. Cerca de súper mercados, farmacias y negocios. Cuentas además con estacionamiento gratuito y seguro con portón automático. Wifi, y SmarTV. Un lugar perfecto y tecnológico para las mejores vacaciones.

Top guest favorite
Home in Santo Domingo
5.0 out of 5 average rating, 18 reviews

Bright and spacious house with pool and terrace.

Bright, spacious, and well-kept house in traditional Santo Domingo, with a great location and beautiful views of the golf course (and the mountains in winter). Cozy terrace with a grill, pool, pool-snooker table, and fully equipped kitchen. Very comfortable and ideal for families. Just a 6-minute walk to the supermarket, restaurants, ice cream/chocolate shop, and pharmacy.

Popular amenities for San Antonio vacation rentals

When is the best time to visit San Antonio?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$12,132 GYDG$11,923 GYDG$11,714 GYDG$11,504 GYDG$11,504 GYDG$11,086 GYDG$10,040 GYDG$10,668 GYDG$10,668 GYDG$10,877 GYDG$11,086 GYDG$12,341 GYD
Avg. temp16°C16°C15°C13°C12°C11°C10°C11°C11°C12°C13°C15°C

Frequently Asked Questions

  • What are the best places to stay in San Antonio?

    Neighborhoods near the city center and the waterfront are popular for their walkability, local cafes, and market access. Some travelers appreciate quieter areas just outside the port for a more relaxed atmosphere.

  • What are the best things to do in San Antonio with kids?

    San Antonio has sandy beaches for families to explore and parks with playgrounds around the city. Kids can enjoy local pastries or visit areas near the port to watch ships and learn about maritime life. Many families also stroll along seaside promenades together.

  • What are some of the best things to do in San Antonio?

    Many enjoy tasting fresh seafood at harbor restaurants, browsing local markets, or joining guided tours of the port. Birdwatching near the coastal wetlands and visiting nearby vineyards are also frequently suggested activities.

  • How is the weather in San Antonio?

    San Antonio has mild, coastal weather—a cool season from May to September with lows around 42°F (5°C) and wetter conditions, while summers are drier and warmer, often reaching 69°F (21°C). A light jacket and layers suit most seasons.

  • When is the best time to visit San Antonio?

    Late spring through early autumn has milder temperatures and less rain, making it a frequently suggested time for exploring the beaches and outdoor markets. The wine harvest season in nearby valleys is also popular among visitors.

  • What are the best places to visit in San Antonio?

    San Antonio has a busy port area, sandy beaches, and a central plaza that often draws visitors. Explore local seafood restaurants, artisan markets, or take in harbor views from the promenade.

  • What are some hiking trails in San Antonio?

    Hiking paths can be found around San Antonio’s coastal areas and natural reserves just outside the city, often featuring ocean views and birdwatching opportunities. Many visitors enjoy casual walks along the waterfront or between neighboring fishing villages.

  • What are some family activities we can do in San Antonio?

    Families explore local beaches, watch fishing boats at the harbor, and enjoy picnics or birdwatching in nearby parks. Small museums and ice cream shops around the city center add to the family-friendly options.

  • What are some of the best day trip ideas from San Antonio?

    Day trips often include exploring the vineyards in the San Antonio Valley, visiting local towns with colonial architecture, or relaxing at scenic beaches along the coast. The nearby Casablanca Valley is also known for its wineries.

  • Are there any pet friendly accommodations available in San Antonio?

    Many rentals in San Antonio welcome pets, especially in coastal neighborhoods or near green spaces. Parks and the beachfront make it convenient for outings with dogs.

  • What are some local tips for visiting San Antonio?

    Try visiting the main fish market early to experience the local trade, and bring cash for smaller vendors. A walk along the promenade around sunset is often recommended for a relaxed experience with coastal views.

  • What is San Antonio known for?

    San Antonio is known for its major seaport, vibrant fishing industry, and links to the wine-producing San Antonio Valley nearby. The city’s culture reflects maritime traditions, fresh seafood, and lively markets.

  • What are the best hidden gems to explore in San Antonio?

    Explore the less-visited docks for glimpses of local fishers at work, visit artisan workshops, or seek murals and street art around the city center. Small seafood cafes near the port often provide a quieter, authentic atmosphere.

  • What are the best foods to try in San Antonio?

    Seafood is a highlight—many visitors try fresh reineta, ceviche, and seafood empanadas. Locally baked sweets and Chilean pastries are also frequently suggested, found at markets and traditional bakeries.

  • What should I bring for a trip to San Antonio?

    Pack light layers for temperatures that shift between about 42–69°F (5–21°C) depending on the season, and bring a rain jacket for wetter months from late autumn to winter. Comfortable walking shoes are helpful for exploring the coastal port and nearby outdoor areas.

  • What is the nightlife in San Antonio like?

    San Antonio’s nightlife is often centered around local pubs, seafood restaurants with live music, and small bars near the harbor. Some venues feature performances by regional musicians, creating a lively yet laid-back atmosphere.

  • What are the most popular events or festivals in San Antonio?

    San Antonio hosts maritime celebrations, cultural festivals, and events tied to the wine harvest season in the surrounding valleys. Local parades, traditional music, and seafood fairs are often highlighted in the community calendar.

  • Are there family friendly vacation rentals in San Antonio?

    San Antonio has a range of vacation rentals that often welcome families, especially in central neighborhoods and residential areas near the beach. Look for listings with kitchens and extra space for a convenient stay.