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Vacation rentals in San Antonio

Find and book unique accommodations on Airbnb

Quick stats about vacation rentals in San Antonio

  • Total vacation rentals

    Explore 60 vacation rentals in San Antonio

  • Nightly prices starting at

    San Antonio vacation rentals start at G$4,186 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,880 verified reviews to help you choose

  • Family-friendly vacation rentals

    30 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 20 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    50 of San Antonio vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Antonio rentals

  • 4.8 Average rating

    San Antonio stays are highly rated by guests—averaging 4.8 out of 5!

Top-rated vacation rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Santo Domingo
4.95 out of 5 average rating, 131 reviews

Santo Domingo, V Region, Spectacular view

House built in 2018 and recently remodeled, bright, modern concept, comfortable. Spectacular ocean view and protected from the wind (250/700 m2), with pool. Main level: large living/dining room, integrated kitchen and terrace, 1 bedroom, 1 bathroom (2nd floor). First floor: indoor and outdoor barbecue grill, living room, 1 bedroom, 1 bathroom, laundry room); 3rd floor (3 bedrooms and 2 bathrooms). Central heating (separate charge). The pool with trees and foliage may have some leaves. Parking for 3 cars.

Guest favorite
A spacious outdoor living area is shaded by a wooden pergola, featuring comfortable wicker seating that faces the ocean. A built-in barbecue is positioned nearby, complemented by coastal views of the rocky shoreline and clear blue skies.
Home in El Quisco
4.9 out of 5 average rating, 160 reviews

Beautiful house with a gazebo and a terrace facing the sea

Get ready for a few days with the best ocean views, restful sleep, and unforgettable moments. Our house is beachfront, with a barbecue, an oceanfront terrace, and a fireplace for cold days. Located in a quiet and secluded area, within walking distance of supermarkets and restaurants. Fully equipped and very comfortable, with everything you need for your stay. To access the house, you have to climb a staircase from the parking lot. It is not suitable for people with reduced mobility.

Guest favorite
Home in Santo Domingo
4.98 out of 5 average rating, 55 reviews

Cozy house with new furniture

Cozy house in Santo Domingo, ideal for relaxing on a large plot with a grassy patio, garden with flowers, and a covered terrace with a grill. The living room has a double-burning fireplace, and the newly remodeled kitchen includes a new washer, dryer, and dishwasher. The beds are new with 400 thread count white sheets and the bunk beds are firm and of excellent quality. Closed parking for 3 cars and Smart TV with over 500 channels (Pluto TV). Perfect for your family getaway!

Guest favorite
Home in Santo Domingo
4.89 out of 5 average rating, 35 reviews

Casa Nueva in Santo Domingo

Unwind as a family and enjoy this cozy space in Huertos Chile. It is designed for those seeking tranquility, comfort, and a connection with nature, without moving far from the coast. Located just 7 minutes (7 km) from Santo Domingo Beach, it offers the best of both the countryside and the sea. Located 15 minutes from Parque Tricao and close to the Maipo River Wetland, the area offers a variety of local cuisine, from ocean-view restaurants to unique culinary experiences.

Guest favorite
A serene view of the Rio Maipo is framed by lush greenery. Various trees and vibrant plants are visible, creating a natural boundary. The calm water reflects the surrounding landscape, inviting tranquil moments in nature.
Cottage in San Antonio
4.85 out of 5 average rating, 66 reviews

Maipo River House

Rustic Family House designed by its owners, with unique furniture and decorations next to the Maipo River in San Antonio. Only an hour's drive from Santiago and Valparaiso. It has different gardens, beautiful flora and fauna of the place. Terrace overlooking the river ideal for breakfast and watching both native and migratory birds in warmer seasons ideal for reconnecting with nature and disconnecting from the day to day of the city. Perfect for people who like nature

Top guest favorite
Cabin in Santo Domingo
5.0 out of 5 average rating, 25 reviews

Tiny House Santo Domingo, Quintral House

Escape to a cozy Tiny House set in nature, located just 8 minutes from Tricao Park. Enjoy a well-deserved rest with an electric Hot Tub, Quincho with grill, in an environment surrounded by native flora and fauna. Located in a gated condominium, offering tranquility and security, and only 10 minutes from Santo Domingo beach. Ideal for couples or small families looking to disconnect from the daily rhythm and reconnect with nature in a comfortable and cozy atmosphere.

Guest favorite
A bright living area features a large window offering expansive views of the ocean. A comfortable rattan chair sits beside a simple coffee table, while a white couch adds contrast. Soft lighting from floor lamps enhances the serene ambiance of the space.
Home in Isla Negra
4.92 out of 5 average rating, 133 reviews

Comfortable house, ocean view in a quiet condominium.

Vacation home in a quiet private condominium. Safe place with access control. Large front yard and parking. Living room, fully equipped kitchen (refrigerator, microwave, oven). Master bedroom with 2 beds of 1.5 places, and second bedroom with 2 beds of 1 place. Large terrace with panoramic ocean views. Equipped bathroom Starlink Internet Attractions: - Pablo Neruda's House: 5 minutes. - Punta de Tralca Beach: 8 min. - Algarrobo Beach: 18 min.

Top guest favorite
A warm living area features a brown leather sofa paired with a natural fiber rug. Plants are arranged on the coffee table and shelf, enhancing the space. Light filters in through large windows, providing a bright ambiance to the cozy setting.
Condo in San Antonio
4.95 out of 5 average rating, 298 reviews

A beautiful apartment in a condominium

Enjoy the simplicity of this quiet and centrally-located accommodation. Ideal for relaxing 3 minutes from downtown San Antonio near beaches.....you are 20 minutes from Tricao Park! 25 minutes from the sea breezes!! 25 from Pablo Neruda's house!! our great Chilean poet Nobel Prize for literature!!!!!!many other beautiful places on our central coast!! and steps from a new viewpoint of our port of San Antonio!! it is beautiful!!!!

Top guest favorite
A spacious sleeping area is showcased, featuring a large bed with a soft green comforter. Floor-to-ceiling windows allow ample natural light, revealing a clear view of the ocean and surrounding landscape. A small seating area is visible on the balcony, complemented by a wall-mounted television.
Apartment in Santo Domingo
4.89 out of 5 average rating, 53 reviews

Kiwi Studio

Kiwi Studio is an ideal place to relax and unwind. It is a 35 m2 studio apartment located in the rocks of Santo Domingo. It has a beautiful clear view of the ocean and the lush nature of the Santa María club. This space, located a few meters from the beach and close to restaurants, has all the amenities you need in a modern and safe environment. It includes a fully equipped kitchen, free parking, towels and bedding.

Superhost
Apartment in San Antonio
4.86 out of 5 average rating, 28 reviews

Beautiful apartment overlooking the ocean - port

Fully equipped apartment, centrally located, with beautiful views of the port. It has a gated terrace, ideal for enjoying amazing sunsets year-round. Excellent connectivity to commerce, restaurants and services. Only 15 minutes from Santo Domingo and the beaches of the coast such as El Tabo, El Quisco and Isla Negra. Ideal for rest, family walks or trips for work. Includes parking inside the condominium.

Superhost
A modern living area features a dark sofa with two yellow cushions. In front, a wooden coffee table holds a candle and decorative items. Floor-to-ceiling windows showcase a serene sunset view, while a soft area rug enhances the inviting space.
Apartment in San Antonio
4.74 out of 5 average rating, 98 reviews

An apartment with an excellent location

Enjoy this quiet and centrally located accommodation, located in the Portal Santo Domingo Condominium, a 7-minute drive from Marbella de Santo Domingo beach and a 13-minute drive from Tricao Park. This apartment is equipped for 4 people, 3 beds, (2 single beds and one double bed) also has a room with a desk, ideal for working, 24-hour security and free parking. Check-in 2:00 pm and Check-out 11:00 am.

Top guest favorite
The image shows a secluded cabin situated on a hillside, surrounded by lush greenery. A small pool is positioned in the foreground, accompanied by a potted palm. The cabin features earthy tones and a sloped roof, enhancing its rustic charm.
Tiny home in Santo Domingo
4.99 out of 5 average rating, 82 reviews

La Playita Lodge

Discover La Playita Lodge, a charming and cozy cabin located behind our property. Designed for those seeking privacy and a romantic atmosphere, this space is perfect for disconnecting from the world and connecting with what really matters. We offer total privacy, although it is part of our property the cabin is completely independent. You'll find cozy touches designed to create unforgettable moments.

Popular amenities for San Antonio vacation rentals

When is the best time to visit San Antonio?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$12,139 GYDG$11,930 GYDG$11,721 GYDG$11,511 GYDG$11,511 GYDG$11,093 GYDG$10,046 GYDG$10,674 GYDG$10,674 GYDG$10,884 GYDG$11,093 GYDG$12,349 GYD
Avg. temp16°C16°C15°C13°C12°C11°C10°C11°C11°C12°C13°C15°C

Frequently Asked Questions

  • What are the best places to stay in San Antonio?

    Neighborhoods near the city center and the waterfront are popular for their walkability, local cafes, and market access. Some travelers appreciate quieter areas just outside the port for a more relaxed atmosphere.

  • What are the best things to do in San Antonio with kids?

    San Antonio has sandy beaches for families to explore and parks with playgrounds around the city. Kids can enjoy local pastries or visit areas near the port to watch ships and learn about maritime life. Many families also stroll along seaside promenades together.

  • What are some of the best things to do in San Antonio?

    Many enjoy tasting fresh seafood at harbor restaurants, browsing local markets, or joining guided tours of the port. Birdwatching near the coastal wetlands and visiting nearby vineyards are also frequently suggested activities.

  • How is the weather in San Antonio?

    San Antonio has mild, coastal weather—a cool season from May to September with lows around 42°F (5°C) and wetter conditions, while summers are drier and warmer, often reaching 69°F (21°C). A light jacket and layers suit most seasons.

  • When is the best time to visit San Antonio?

    Late spring through early autumn has milder temperatures and less rain, making it a frequently suggested time for exploring the beaches and outdoor markets. The wine harvest season in nearby valleys is also popular among visitors.

  • What are the best places to visit in San Antonio?

    San Antonio has a busy port area, sandy beaches, and a central plaza that often draws visitors. Explore local seafood restaurants, artisan markets, or take in harbor views from the promenade.

  • What are some hiking trails in San Antonio?

    Hiking paths can be found around San Antonio’s coastal areas and natural reserves just outside the city, often featuring ocean views and birdwatching opportunities. Many visitors enjoy casual walks along the waterfront or between neighboring fishing villages.

  • What are some family activities we can do in San Antonio?

    Families explore local beaches, watch fishing boats at the harbor, and enjoy picnics or birdwatching in nearby parks. Small museums and ice cream shops around the city center add to the family-friendly options.

  • What are some of the best day trip ideas from San Antonio?

    Day trips often include exploring the vineyards in the San Antonio Valley, visiting local towns with colonial architecture, or relaxing at scenic beaches along the coast. The nearby Casablanca Valley is also known for its wineries.

  • Are there any pet friendly accommodations available in San Antonio?

    Many rentals in San Antonio welcome pets, especially in coastal neighborhoods or near green spaces. Parks and the beachfront make it convenient for outings with dogs.

  • What are some local tips for visiting San Antonio?

    Try visiting the main fish market early to experience the local trade, and bring cash for smaller vendors. A walk along the promenade around sunset is often recommended for a relaxed experience with coastal views.

  • What is San Antonio known for?

    San Antonio is known for its major seaport, vibrant fishing industry, and links to the wine-producing San Antonio Valley nearby. The city’s culture reflects maritime traditions, fresh seafood, and lively markets.

  • What are the best hidden gems to explore in San Antonio?

    Explore the less-visited docks for glimpses of local fishers at work, visit artisan workshops, or seek murals and street art around the city center. Small seafood cafes near the port often provide a quieter, authentic atmosphere.

  • What are the best foods to try in San Antonio?

    Seafood is a highlight—many visitors try fresh reineta, ceviche, and seafood empanadas. Locally baked sweets and Chilean pastries are also frequently suggested, found at markets and traditional bakeries.

  • What should I bring for a trip to San Antonio?

    Pack light layers for temperatures that shift between about 42–69°F (5–21°C) depending on the season, and bring a rain jacket for wetter months from late autumn to winter. Comfortable walking shoes are helpful for exploring the coastal port and nearby outdoor areas.

  • What is the nightlife in San Antonio like?

    San Antonio’s nightlife is often centered around local pubs, seafood restaurants with live music, and small bars near the harbor. Some venues feature performances by regional musicians, creating a lively yet laid-back atmosphere.

  • What are the most popular events or festivals in San Antonio?

    San Antonio hosts maritime celebrations, cultural festivals, and events tied to the wine harvest season in the surrounding valleys. Local parades, traditional music, and seafood fairs are often highlighted in the community calendar.

  • Are there family friendly vacation rentals in San Antonio?

    San Antonio has a range of vacation rentals that often welcome families, especially in central neighborhoods and residential areas near the beach. Look for listings with kitchens and extra space for a convenient stay.