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Vacation rentals in San Antonio

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in San Antonio

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A private outdoor jacuzzi is surrounded by lush green plants, adding a natural ambiance to the space. The wooden deck features steps leading to the jacuzzi, complemented by modern lighting fixtures mounted on the wall, enhancing the serene atmosphere.
Apartment in San Antonio
4.99 out of 5 average rating, 75 reviews

Cozy Apartment in El Peñón with Jacuzzi and Gym

★Location, Location, Location.★ Welcome to your spacious home away from home in the heart of Cali! This 1775 sq ft apartment, located in El Peñón, a safe and gastronomic neighborhood, offers everything you need for a comfortable stay. It's just across the street from San Antonio and within walking distance to major city attractions. The apartment features a private patio with gym and jacuzzi, a king-size bed, fully stocked kitchen, safety box, balcony, 250 Mbps WiFi, and two dedicated workspaces

Guest favorite
Apartment in San Antonio
4.91 out of 5 average rating, 75 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favorite
The spacious living area features a green sofa adorned with colorful cushions, positioned against a white wall. A large area rug adds warmth under a wooden coffee table. Natural light fills the space through expansive windows, complemented by decorative plants and a textured wall hanging.
Apartment in Santa Teresita
4.95 out of 5 average rating, 38 reviews

Rustic Private APT Near Gato de Tejada -7 Min Walk

Welcome to Indigo! This quiet one-bedroom, one-bathroom unit, is the perfect match for families, couples, solo travelers. We are sure you’ll be impressed with the comfort, style, and sophistication the apartment provides. Immerse yourself into Cali and its magical essence while enjoying our Apartment. Be inspired by its unique location and find yourself mesmerized by everything Cali offers, ranging from top-tier restaurants, bars, shops, and nightlife experiences. We are ready for your visit!

Superhost
An open living space displays a comfortable hammock suspended near a large wooden table. The natural light floods in through a window, highlighting the modern kitchen area with stools and a decorative plant. Rustic wood accents and soft textures add warmth to the environment.
Apartment in Juanambu
4.89 out of 5 average rating, 103 reviews

Explore Cali from an Exquisite & Spacious 1BR Apt

Casa Reyka is our newly-renovated historic estate situated in the most emblematic part of Cali. It is charming, safe and has plenty of personality. Our mission during renovation was to present the past as the focal point. You'll find each detail in this beautiful house tells a unique story with rustic, colonial & contemporary aesthetics. Through our use of reclaimed bricks, beams, window frames and doors you'll be transported to the past while enjoying the many modern amenities of today.

Guest favorite
A bright sleeping area features a spacious bed adorned with decorative pillows. Exposed brick arches highlight the stylish design. Soft lighting is provided by a hanging lamp, while natural light enters from a nearby window, illuminating warm wooden floors.
Apartment in San Antonio
4.87 out of 5 average rating, 83 reviews

Beautiful Colonial Apartment San Antonio Centre

The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Guest favorite
A terrace area is shown, featuring a table set for breakfast with two plates of food, glasses of orange juice, and fresh fruit. A flowering plant sits on the table. The backdrop includes a cityscape with modern buildings and a clear blue sky with clouds.
Apartment in San Antonio
4.91 out of 5 average rating, 64 reviews

San Antonio Suite with Terrace & Panoramic View

It is located in San Antonio, touristic, and very central area of Cali. You’ll be just a few minutes’ walk from restaurants, cafés, salsa dancing spots, salsa academies, supermarkets, and tourist attractions. It is an excellent option for guests staying several days, working remotely, visiting family, or looking for a comfortable and quiet place to rest. You can also enjoy the building’s terrace, with beautiful views, sunsets, the Cali breeze, and the chance to see macaws.

Guest favorite
Apartment in San Antonio
4.96 out of 5 average rating, 184 reviews

OM Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Guest favorite
Apartment in San Antonio
4.9 out of 5 average rating, 105 reviews

402Studio with balcony in top area + AC and Netflix

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Top guest favorite
A modern living space features a cozy seating area with a light blue chair and a gray sofa. A sleek kitchen with barstool seating is highlighted, complemented by contemporary pendant lighting and a stylish backsplash. Natural light fills the room, enhancing the vibrant decor.
Apartment in El Peñol
4.96 out of 5 average rating, 165 reviews

Penthouse Jacuzzi • El Peñón's Best Location

🌴 EXSTR Apartment • Villa del Peñon 401 🫧 Soak in your own open-air jacuzzi on a private terrace in one of Cali’s best locations. This 2-bedroom, 2.5-bath penthouse is perfect for couples, friends, or remote workers. Enjoy A/C, fast Wi-Fi, SmartTVs, a full kitchen, and fresh linens every 4 days. Walk to top restaurants, bars, and San Antonio in minutes. A relaxing, high-comfort stay in the city’s most walkable, cultural neighborhood.

Guest favorite
An open-plan living space features a dining table with four chairs adjacent to a modern kitchen. A comfortable sofa is positioned nearby, and large sliding glass doors showcase outdoor greenery. Warm lighting creates a cozy atmosphere, complemented by decorative elements like natural fibers.
Apartment in Juanambu
4.92 out of 5 average rating, 128 reviews

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI

** EXCLUSIVE UNIT WITHOUT AIRBNB SERVICE FEES ** Welcome to our luxurious loft in Cali, inspired by nature. Measuring 44 m² (474 sq. ft.), with a private outdoor Jacuzzi, and sleeping 2, it is a contemporary oasis. The living room, dining room, and equipped kitchen offer comfort and style. A private bedroom and full bathroom ensure a restful night's sleep. An unbeatable location close to tourist attractions.

Guest favorite
A modern dining area features a wooden table surrounded by two black woven chairs. A simple vase holds decorative dried foliage, positioned on the table. Stylish cabinetry with warm lighting enhances the contemporary ambiance, complemented by decorative items displayed on the shelves.
Apartment in San Antonio
4.91 out of 5 average rating, 120 reviews

Exclusive Duplex Apartment

✨ Bienvenido a tu dúplex en San Antonio ✨ Disfruta de este acogedor y moderno apartamento de dos niveles, ideal para una estadía cómoda y funcional. Cuenta con cama queen, sofá cama, aire acondicionado y cocina equipada. Ubicado en una zona vibrante y caminable, cerca de restaurantes, cafés y vida cultural. Perfecto para vivir Cali con estilo, comodidad y una excelente ubicación.

Guest favorite
Loft in Cali
4.88 out of 5 average rating, 26 reviews

Colonial Loft with Rooftop, AC and Fast WiFi

Discover a studio-style loft inside a restored colonial home, just four blocks from the traditional San Antonio neighborhood. Perfect for solo travelers or couples, it offers air conditioning, fast WiFi, a fully equipped kitchen, and access to a shared rooftop terrace with city views. An ideal location close to cafés, restaurants, and Cali’s main tourist attractions.

Popular amenities for San Antonio vacation rentals

  1. Airbnb
  2. Colombia
  3. Valle del Cauca
  4. Cali
  5. San Antonio