
Vacation rentals in San Antonio
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Top-rated vacation rentals in San Antonio
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Suite in San Antonio with Private Patio and Rooftop
Located in the charming San Antonio neighborhood in Cali. You'll be within walking distance of Bulevar del Río, Calle del Sabor, restaurants, coffee shops, museums, bars, salsa schools, and supermarkets, as well as attractions such as the Cali Zoo, Cristo Rey, the Botanical Garden, and Gato de Tejada. It is a quiet space, ideal for a good night's sleep or working remotely, and it has a perk that is hard to find in the city center: a private patio with an outdoor dining area, perfect for having breakfast or dinner al fresco.

Cozy Apartment in El Peñón with private Jacuzzi
★Location, Location, Location.★ Welcome to your spacious home away from home in the heart of Cali! This 1775 sq ft apartment, located in El Peñón, a safe and gastronomic neighborhood, offers everything you need for a comfortable stay. It's just across the street from San Antonio and within walking distance to major city attractions. The apartment features a private patio with gym and jacuzzi, a king-size bed, fully stocked kitchen, safety box, balcony, 250 Mbps WiFi, and two dedicated workspaces

Cozy+Unique Loft/Touch of Nature/High Speed WiFi
*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Rustic Private APT Near Gato de Tejada -7 Min Walk
Welcome to Indigo! This quiet one-bedroom, one-bathroom unit, is the perfect match for families, couples, solo travelers. We are sure you’ll be impressed with the comfort, style, and sophistication the apartment provides. Immerse yourself into Cali and its magical essence while enjoying our Apartment. Be inspired by its unique location and find yourself mesmerized by everything Cali offers, ranging from top-tier restaurants, bars, shops, and nightlife experiences. We are ready for your visit!

Explore Cali from an Exquisite & Spacious 1BR Apt
Casa Reyka is our newly-renovated historic estate situated in the most emblematic part of Cali. It is charming, safe and has plenty of personality. Our mission during renovation was to present the past as the focal point. You'll find each detail in this beautiful house tells a unique story with rustic, colonial & contemporary aesthetics. Through our use of reclaimed bricks, beams, window frames and doors you'll be transported to the past while enjoying the many modern amenities of today.

Beautiful Colonial Apartment San Antonio Centre
The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

OM Studio Rooftop at San Antonio - Cali.
Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

402Studio with balcony in top area + AC and Netflix
Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI
** EXCLUSIVE UNIT WITHOUT AIRBNB SERVICE CHARGE ** Welcome to our luxurious loft in Cali, inspired by nature. Measuring 44 m² (474 sq. ft.), with a private outdoor Jacuzzi, and sleeping 2, it is a contemporary oasis. The living room, dining room, and equipped kitchen offer comfort and style. A private bedroom and full bathroom ensure a restful night's sleep. An unbeatable location close to tourist attractions. IT DOES NOT HAVE HOT WATER.

Penthouse Jacuzzi • El Peñón's Best Location
🌴 EXSTR Apartment • Villa del Peñon 401 🫧 Soak in your own open-air jacuzzi on a private terrace in one of Cali’s best locations. This 2-bedroom, 2.5-bath penthouse is perfect for couples, friends, or remote workers. Enjoy A/C, fast Wi-Fi, SmartTVs, a full kitchen, and fresh linens every 4 days. Walk to top restaurants, bars, and San Antonio in minutes. A relaxing, high-comfort stay in the city’s most walkable, cultural neighborhood.

Exclusive Duplex Apartment
✨ Bienvenido a tu dúplex en San Antonio ✨ Disfruta de este acogedor y moderno apartamento de dos niveles, ideal para una estadía cómoda y funcional. Cuenta con cama queen, sofá cama, aire acondicionado y cocina equipada. Ubicado en una zona vibrante y caminable, cerca de restaurantes, cafés y vida cultural. Perfecto para vivir Cali con estilo, comodidad y una excelente ubicación.

Colonial Loft with Rooftop, AC and Fast WiFi
Discover a studio-style loft inside a restored colonial home, just four blocks from the traditional San Antonio neighborhood. Perfect for solo travelers or couples, it offers air conditioning, fast WiFi, a fully equipped kitchen, and access to a shared rooftop terrace with city views. An ideal location close to cafés, restaurants, and Cali’s main tourist attractions.
Popular amenities for San Antonio vacation rentals
Other great vacation rentals in San Antonio

Private Jacuzzi Pad • Walk Anywhere • El Peñón

Upper-Floor Gem | Stunning City Views

S23 - Elegant Penthouse near San Antonio

Casa Colonial San Antonio - Charming terrace

Entire Home Luxury Duplex in Cali

Luxury Loft • Best Area • Jacuzzi + 24/7 Sec

2-Bed With Nice Balcony • El Peñon Best Location

“Stunning Colonial Oasis in the Heart of Cali”
Destinations to explore
- Chipichape Centro Comercial
- Estadio Olímpico Pascual Guerrero
- Parque del Perro
- Zoologico de Cali
- Basilica of the Lord of Miracles
- Unicentro Cali Shopping Mall
- Palmetto Plaza
- Jardín Plaza
- Ingenio Park
- La Topa Tolondra
- Parque Artesanal Loma De La Cruz
- The River Cat
- Galería Alameda
- Iglesia De San Antonio
- Hacienda El Paraiso
- Parque de los Gatos
- Cosmocentro
- Plazoleta Jairo Varela
- Museo La Tertulia
- Iglesia La Ermita
- Estatua de Sebastian de Benalcazaz
- Museum Sugarcane
- Teatro Jorge Isaacs
- La Merced Church





