
Vacation rentals in San Antonio
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in San Antonio
Guests agree: these stays are highly rated for location, cleanliness, and more.

Cozy+Unique Loft/Touch of Nature/High Speed WiFi
*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Spacious & cool apartment in El Peñon
Discover the charm of Cali in this completely renovated apartment, located in the heart of the trendies neighborhood of Cali. Equipped with everything you need to feel at home, from a French press with Colombian coffee to modern appliances such as an airfryer and blender. Two big screen TVs with Netflix for entertainment, washing machine, iron and more, ensuring a comfortable stay. El Peñon is one of the most famous neighborhoods in Cali, with some of the best restaurants, bars and clubs!

Panoramic Suite Overlooking Colonial Cali
Magical View Suite – Colonial Design in San Antonio Experience the soul of Cali from this cozy suite with an unforgettable view In the historic heart of San Antonio, just steps from Hotel Colina, the space blends colonial charm, local art, and a serene atmosphere designed for rest and inspiration Perfect for travelers seeking history, culture, and gastronomy without giving up modern comforts: a fully equipped kitchen, hot water, reliable Wi-Fi, and a postcard-perfect view from the window

Villa del Peñon 101 - 2-Bed, 2-Bath | Fast WiFi
🌴 EXSTR APARTMENT • Villa del Peñon 101 Villa del Peñon unit 101 with two bedrooms and two bathrooms, is the perfect match for families, groups of friends, executives and digital nomads. All tabs have hot water, all rooms have A/C, smart TVs, and queen beds. All the amenities are in place and built with your comfort in mind. The El Peñon neighborhood is a very walkable area with plenty of restaurants and entertainment within minutes. Colonial San Antonio is only 3 blocks away.

Beautiful apartment in El Peñon
Luxury apartment located in the exclusive El Peñón neighborhood, the heart of the traditional hotel area of western Cali. Surrounded by a variety of restaurants, bars, nightclubs and cultural areas, close to emblematic sites such as the La Tertulia Museum, the Obelisk, the Cali Zoo, the Cerro de las Tres Cruces, the Gato del Río, the Bulevar del Río, San Antonio and Granada. Perfect for those looking for comfort, style and an unbeatable location to enjoy and explore the city.

302 Balcony, A/C, Netflix and fast WiFi – Studio 302
Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the 5-star Dann Carlton Hotel, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passing of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

H603 Private Jacuzzi | Balcony with Panoramic Views |
** EXCLUSIVE UNIT WITHOUT AIRBNB SERVICE FEES ** Located in the quiet Cristales neighborhood of Cali, this 48m² loft with a private Jacuzzi and an impressive view of Cali, perfect for up to 4 people, is fully equipped for your comfort. The building has amenities such as: coworking, gym, jacuzzis, picnic area, outdoor cinema, and more. Just minutes from Parque del Perro, it combines tranquility, modernity, and comfort in a perfect setting for your stay!

Stylish Studio with Rooftop and AC in San Antonio
Welcome to Cali’s historic San Antonio district. This early-1900s home was thoughtfully restored into a modern, chic condo in 2023. Located in a private 5-unit building, it offers comfort and character just steps from cafés, galleries, and local cuisine. Feel the Cali breeze, walk to top salsa spots, and experience the city like a local. Your Cali-born host is happy to assist in English or Spanish.

IN105 Luxury Oasis | Private Jacuzzi | 350mb WIFI
** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** Welcome to our luxurious loft in Cali, inspired by nature. With 44m², a private outdoor Jacuzzi and space for 4 people, it is a contemporary oasis. Living room, dining room, and equipped kitchen offer comfort and style. A private room and full bathroom guarantee a restful night's sleep. Unbeatable location near tourist spots.

Exclusive Duplex Apartment
Welcome to our newly renovated duplex apartment in the heart of San Antonio! Embrace the latest design trends in this luxurious space where comfort meets style. Enjoy the vibrant atmosphere of the city right at your doorstep. Feel at home as you indulge in modern amenities and soak in the energy of this bustling neighborhood. Your perfect urban getaway awaits!

Private Flat - LOFT at San Antonio - Cali
The flat is located in the historic neighborhood of San Antonio, Cali. A cultural, tourist and residential area in western Cali. It's a 2 story building placed in the back of an old house that´s been restorated. Kitchen, fridge, coffee maker, oven, gas stove, blender, silverware, pans, plates, bowls, hot water, wi-fi.

Colonial House | Historic Center | Cristo Rey View
Welcome to La Casa de Río! A colonial refuge where warm light embraces and the tropical breathes in every corner. We are in the heart of the Historic Center, steps from restaurants, cafes, and salsa bars. Here you'll find premium rest and a perfect home for up to 6 travelers.
Popular amenities for San Antonio vacation rentals
Other great vacation rentals in San Antonio

El Diamante apartment with green views next to Granada

Beautiful house in an excellent colonial location

San Antonio Un Lugar Mágico A 5M Bulevar Del Rio

Balcony Suite; Peñón

F°eel the Rhythm: A Salsa Capital Best Location!

modern apartment in the heart of the best area

Downtown | Remote Work: Private Patio & Rooftop

City Nest – Cozy in La Merced
Destinations to explore
- Chipichape Centro Comercial
- Estadio Olímpico Pascual Guerrero
- Basilica of the Lord of Miracles
- Zoologico de Cali
- Parque del Perro
- Acuaparque de la Cana
- La Topa Tolondra
- Pontificia Universidad Javeriana Cali
- Ingenio Park
- Parque de los Gatos
- The River Cat
- Coliseum of the People
- Palmetto Plaza
- Parque Artesanal Loma De La Cruz
- Unicentro Cali Shopping Mall
- Jardín Plaza
- Parque Versalles
- Cosmocentro
- Estatua de Sebastian de Benalcazaz
- Iglesia De San Antonio
- Hacienda El Paraiso
- Plazoleta Jairo Varela
- Iglesia La Ermita
- Museo La Tertulia




