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Vacation rentals in San Antonio

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Top-rated vacation rentals in San Antonio

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A spacious outdoor seating area is featured, furnished with a deep blue cushioned sectional and a wooden coffee table. Two glasses and a bottle of wine are arranged on the table, set against a backdrop of cloudy skies.
Apartment in San Antonio
4.91 out of 5 average rating, 166 reviews

Beautiful modern flat with Roofdeck in San Antonio

Beautiful apartment in the historical neighbourhood. It offers a quiet and peaceful environment within the most exciting part of town, close to all main points of interest. Suitable for travellers, couples, families, business visitors and digital nomads. Internet connexion 100 Mbs. Roof deck with view over the city. Fully equipped kitchen, TVs, Netflix, 2 bedrooms. You'll enjoy a whole apartment for yourself, with private access, independence along within the security of a solid, modern house.

Guest favorite
A staircase with black metal steps leads upward, set against a backdrop of exposed brick wall. Natural light flows through large wooden windows with bars, illuminating a decorative plant in a woven basket and a glass bottle on the floor.
Apartment in San Antonio
4.91 out of 5 average rating, 53 reviews

Cozy+Unique Loft/Touch of Nature/High Speed WiFi

*BRAND NEW* rustic yet luxurious & modern loft located in San Antonio. Walking distance from Cali's best restaurants, top bars/night clubs! Centrally located in Cali's famous artistic & colonial neighborhood of San Antonio, this chic loft comes equipped with everything you need for a comfortable stay. Full kitchen, queen sized beds, workspace, AC, washer, Smart TV, & more! If you are looking for a true cultural urban experience, with all of the amenities & comfort, then this is your place.

Guest favorite
A bright sleeping area features a spacious bed adorned with decorative pillows. Exposed brick arches highlight the stylish design. Soft lighting is provided by a hanging lamp, while natural light enters from a nearby window, illuminating warm wooden floors.
Apartment in San Antonio
4.87 out of 5 average rating, 68 reviews

Beautiful Colonial Apartment San Antonio Centre

The house is right in the middle of San Antonio, but without having to walk up any of the area's steep hills. Beautiful, tranquil Colonial home with original architecture located in Cali's most popular neighbourhood. This oasis has a running fountain. The house has this private apartment and three separate bedrooms. Here you are only seconds away from restaurants, cafes, bars, a park and salsa schools. The house has two floors with different areas to socialise, chill, read and work.

Guest favorite
Apartment in San Antonio
4.88 out of 5 average rating, 43 reviews

Casa Balita - Design and History - Loft Duplex

Enjoy this cozy stay at Casa Balita, ideally located in the traditional San Antonio neighborhood, a cultural and architectural heritage, on Cobblestone Street. The area offers a wide range of dining and cultural experiences. Just a few meters away, explore the El Peñón neighborhood, and only two blocks away, the iconic Loma de San Antonio with its beautiful church. Additionally, the accommodation features a shared terrace with a city view. An ideal place for your stay in Cali!

Guest favorite
Apartment in San Antonio
4.89 out of 5 average rating, 102 reviews

Luxurious Studio in San Antonio

Indulge in the unmatched luxury of this recently renovated studio, boasting a unique and truly extraordinary style. Perfect for those in search of comfort and relaxation without compromising on location, this studio is nestled in the heart of San Antonio, Cali's most distinguished neighborhood. Immerse yourself in a lively setting surrounded by the city's finest local restaurants and a captivating atmosphere. It presents an exceptional combination of opulence and convenience.

Guest favorite
A bright, open-plan living area features a kitchen with turquoise cabinets and a dining table. Two stools and a black ottoman provide seating options. A textured rug lies on the tiled floor, and large glass doors invite natural light while connecting the space to the outdoors.
Apartment in San Antonio
4.96 out of 5 average rating, 140 reviews

Stylish Studio Rooftop at San Antonio - Cali.

Om Studio Rooftop es un lugar para disfrutar de la tranquilidad y del ambiente que tiene. Deléitate con la brisa que baja de las montañas y el canto de los loros al atardecer, acompáñalo con una copa de vino, complácete con una taza de café al despertar, toma una ducha al aire libre y gózate el sol en la terraza en las mañanas. En las noches aprovecha todo lo que tiene el barrio San Antonio para darte. Un espacio único en el corazón de la sucursal del cielo.

Top guest favorite
Apartment in San Antonio
4.93 out of 5 average rating, 136 reviews

302 studio apartment in El Peñon/San Antonio

Located in El Peñón, one of the safest and quietest neighborhoods in Cali. Steps from the Hotel Dann Carlton 5⭐️, surrounded by restaurants, bars, nightclubs, casino, museum and park. We have air conditioning, fast WiFi, TV with streaming apps and a free 24/7 laundry area. You can hear the passage of vehicles. Ideal for enjoying the city in comfort and an excellent location. In addition, we offer a clean, cozy environment with quick attention to any need.

Top guest favorite
A modern living space features a cozy seating area with a light blue chair and a gray sofa. A sleek kitchen with barstool seating is highlighted, complemented by contemporary pendant lighting and a stylish backsplash. Natural light fills the room, enhancing the vibrant decor.
Apartment in El Peñol
4.96 out of 5 average rating, 160 reviews

Penthouse Jacuzzi • El Peñon's Best Location

🌴 EXSTR APARTMENT • Villa del Peñon 401 Soak in your own open-air jacuzzi on a private terrace in one of Cali’s best locations. This 2-bedroom, 2.5-bath penthouse is perfect for couples, friends, or remote workers. Enjoy A/C, fast Wi-Fi, SmartTVs, a full kitchen, and fresh linens every 4 days. Walk to top restaurants, bars, and San Antonio in minutes. A relaxing, high-comfort stay in the city’s most walkable, cultural neighborhood.

Superhost
The bedroom area is situated on a mezzanine, featuring a spacious bed dressed in crisp white linens. A wall-mounted television displays a scenic view of Cali. Large windows allow natural light to flood the space, enhancing the view of the surrounding greenery.
Apartment in Centenario
4.88 out of 5 average rating, 86 reviews

IN701 Quiet duplex | Central location | Views

** EXCLUSIVE UNIT WITH NO AIRBNB SERVICE FEE ** This spectacular 38 sq. meters duplex + 18 sq. meters of quiet and central storage, is located in one of the best places for tourists, a short walk from the city's main tourist attractions. Designed for short or long stays, it has all the comforts to feel at home. Modern industrial type avant-garde design, with a double height window that looks towards the hills of Cali.

Guest favorite
An outdoor terrace is shown, featuring a rustic wooden railing adorned with potted plants. A comfortable seating area with a patterned cushion invites relaxation, while the landscape reveals lush greenery and a distant city view in the background.
Loft in San Antonio
5 out of 5 average rating, 7 reviews

Quiet apartment, private terrace & amazing view

Peaceful and centrally located loft-type private apartment, with no busy traffic noice nearby (rare!). Lots of green plants and the most amazing view over the city. Ideal for female travellers and eco-friendly people: it's furnished according to sustainability and health - stainless steel pots, fan instead of A/C, biodegradable washing soap. Free parking, which is not private, it's on the street in front of the house.

Top guest favorite
Apartment in Santa Isabel
5 out of 5 average rating, 15 reviews

Entire Home Luxury Duplex in Cali

Discover a modern and cozy space in this duplex with city views. Enjoy a warm atmosphere with a living room, dining area, fully equipped kitchen, and two private bathrooms—offering everything you need for a restful stay. Ideal for 1 to 4 guests looking for comfort and a privileged location. Just minutes away from Parque del Perro, where you can experience Cali’s gastronomy, unique cafés, and vibrant salsa culture.

Guest favorite
The living area features a neutral-toned sofa bed and a circular coffee table with a decorative plant. Two chairs are positioned beside a window, offering a view of the city lights. The space is illuminated by warm lighting, enhancing the evening ambiance.
Apartment in Santa Teresita
4.9 out of 5 average rating, 41 reviews

Modern with a nice view of the city

Experience a dream getaway in Cali. Discover comfort and elegance in this cozy 50m² apartment located in the heart of western Cali, in the Riomaggiore Building. Let yourself be enveloped by the city's vibrant atmosphere and enjoy a memorable stay with all the amenities this new building has to offer. Its strategic location places it a few steps away from Cali's best gastronomic areas, museums, and tourist sites.

Popular amenities for San Antonio vacation rentals

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