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Vacation rentals in Santo Domingo

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Tiny home in Guatape

4.98 out of 5 average rating, 336 reviews

Foresta: Cabin with views of the lake & rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour. You choose!

Jan 10 – 17

G$24,628 GYD per night
Guest favorite

Cabin in El Peñol

5.0 out of 5 average rating, 63 reviews

Milagros Home

🍃Milagros Home es una cabaña excepcional, con muchos espacios en un solo lugar, con vista al embalse del Peñol-Guatape, lo que te permite disfrutar de un paisaje y unos amaneceres de ensueño. Ni con las mejores fotografías te puedo explicar lo que se siente estar aquí, es un lugar donde sientes que se detiene el tiempo y te haces uno con el entorno. Es una sola cabaña, así q todos los espacios son solo para ti. Por supuesto que aceptamos mascotas, pues ellas son parte de nuestra familia!🍃

Mar 2 – 9

G$24,866 GYD per night
Guest favorite

Dome in Guatapé

4.85 out of 5 average rating, 139 reviews

Guatepe Dome Glamping with pool and jacuzzi

Glamping Dome with Magnificant views of the mountains and lake - only a 5 minute drive to the town of Guatape & 'The Rock' (El Peñón de Guatapé) where you can climb 749 steps to the top for breathtaking views! Includes: King Size Bed, TV, and coffee machine and mini fridge. Property has a gorgeous POOL, heated JACUZZIS, patio with BBQ, x-large suspended hammock. *Pool shared, Jacuzzis private. *Contact owner for boat or helicopter trips, jet ski & ATV rentals, massage therapist & more...

Aug 14 – 21

G$27,876 GYD per night

Popular amenities for Santo Domingo vacation rentals

Other great vacation rentals in Santo Domingo

Guest favorite

Cottage in Barbosa

4.96 out of 5 average rating, 46 reviews

Cozy cottage with a pool

Apr 30 – May 7

G$16,651 GYD per night
Superhost

Tiny home in Alejandría

4.83 out of 5 average rating, 41 reviews

Eco-friendly cabin in natural reserve

Sep 13 – 20

G$4,103 GYD per night
Guest favorite

Home in Vereda Los Naranjos

4.95 out of 5 average rating, 56 reviews

Finca Colibri Guatape Artist Lakehouse near Luxe!

Dec 7 – 14

G$22,747 GYD per night
Guest favorite

Cabin in Vereda Curazao

5.0 out of 5 average rating, 14 reviews

Wellness cabin in Copacabana

Jul 9 – 16

G$21,357 GYD per night
Guest favorite

Cabin in Rionegro

4.93 out of 5 average rating, 84 reviews

Nature & View

Jan 29 – Feb 5

G$15,030 GYD per night
Guest favorite

Tiny home in Peñol

4.96 out of 5 average rating, 26 reviews

Tiny lake house, private cabin, natural refuge

Apr 5 – 12

G$54,035 GYD per night
Guest favorite

Home in Don Diego

5.0 out of 5 average rating, 6 reviews

Sky-High Luxury Award-Winning House in the Clouds

Dec 10 – 17

G$218,452 GYD per night
Guest favorite

Villa in El Peñol

4.85 out of 5 average rating, 13 reviews

AquaVilla Crystal Spring Guatape

Jan 4 – 11

G$130,056 GYD per night
Guest favorite

Loft in Medellín

5.0 out of 5 average rating, 14 reviews

Provenza Penthouse • Jacuzzi • AC • Steam Shower

Apr 8 – 15

G$116,472 GYD per night
Guest favorite

Villa in Medellín

5.0 out of 5 average rating, 25 reviews

Hilltop Enchanting Villa w/ Stunning Views+Jacuzzi

May 25 – Jun 1

G$155,871 GYD per night
Guest favorite

Cottage in San José

5.0 out of 5 average rating, 13 reviews

Tierra Nova Cab

Jul 13 – 20

G$19,039 GYD per night
Superhost

Home in Envigado

5.0 out of 5 average rating, 17 reviews

Lake Mansion in alto palmas, Pool / Poblado 15Min

Jul 21 – 28

G$151,302 GYD per night

Destinations to explore

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Santo Domingo