We’re sorry, some parts of the Airbnb website don’t work properly without JavaScript enabled.

Airbnb your place

Airbnb your place

Lake side house rentals in Lake Santa Fe

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Lake Santa Fe

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

1 of 3 pages

Cottage in Hawthorne

4.85 out of 5 average rating, 109 reviews

Live Oak Oasis on Morris Lake

Unspoiled nature greets your every turn at this charming 650 SF lakefront retreat. A short distance from 10 of Florida's finest 1st magnitude springs, ranging from 30 - 90 minute drive, makes the location a perfect basecamp for adventure travel. Rest beneath the shade of Live oaks that pull the breeze ashore. Enjoy Sand hill cranes and hummingbirds from the cabana. Incredible sunsets from new dock. Paddle boat & paddle boards available for adventures. WiFi, Netflix, Laundry, HOT outdoor shower!

Oct 14 – 21

G$20,520 GYD per night

Home in Earleton

4.97 out of 5 average rating, 177 reviews

Lake House Escape & Play

1950's remodeled home. Dock access is approx 500ft from house down to Big Lake Santa fe 7x3mi & up to 30ft deep. Perfect for skiing & fishing. Boat trailer between houses or along road. Use of dock & canoe free. The vacation venue next door, called "Boat House", has a boat ramp. It is $20 fee to launch boat or free ramp in Melrose, 3.5mi away. PLEASE be careful at dock. It is very sturdy but the hurricanes have washed out the sides. Grab 1 of the flashlights for a night walk to guide you.

Jul 8 – 15

G$24,224 GYD per night

Cabin in Branford

5.0 out of 5 average rating, 123 reviews

Sweetbay River Camp-Ichetucknee River Access

Come enjoy a peaceful getaway on four private acres *near* the Ichetucknee and the Santa Fe rivers! Float the crystal clear river, take your boat out, or just hang in the hammock and enjoy a bonfire! The cabin is in a wildlife sanctuary, so you will see many deer and other animals in the yard and around the neighborhood. The house comes with private access to an Ichetucknee tube/kayak launch as well as the exit point and a private boat ramp. Only four miles to Ichetucknee Springs State Park!

Dec 17 – 24

G$27,952 GYD per night

Cabin in Hawthorne

4.95 out of 5 average rating, 129 reviews

Charming Lakefront Log Home

Welcome to your perfect lake retreat! Located on a no public access lake. This charming log home has a private dock and boat ramp suitable for launching your boat for fishing or skiing. There are kayaks on premises for use. This is an ideal location to enjoy North Florida’s lake life with family, friends, or work retreat. Includes a fully stocked kitchen, covered porch, fire pit, gas grill, and WiFi if you feel the need to plug in. NOT suitable for parties or events. NO loud noise, please.

Sep 23 – 30

G$35,748 GYD per night

Apartment in Melrose

4.88 out of 5 average rating, 168 reviews

The Orchid of Lake Santa Fe

Melrose Bay on Lake Santa Fe This apartment is newly remodeled. It features new cabinets, new appliances, a private porch and lovely furnishings, WIFI and cable. Downtown Melrose is in walking distance with three restaurants (one is the famous Blue Water Bay), public library, post office, grocery store, dollar store and Ace. Bring your boat and launch at the nearby boat ramp. Lake Santa Fe is a recreational lake with clean spring fed water for swimming, boating, skiing and fishing.

Oct 3 – 10

G$19,801 GYD per night

Home in Micanopy

4.97 out of 5 average rating, 221 reviews

Beautiful House, Historic District, Micanopy

My Beautiful House is located in the heart of the historic district of Micanopy, Florida. Relaxing is a breeze in this wonderful home. Two large bedrooms and two equally spacious living areas are furnished with comfort in mind. There are two televisions with Directv service and free WiFi. The large backyard has lots of space and privacy! Established in 1821, Micanopy is the oldest inland town and the town that time forgot. Convenient to both Gainesville and Ocala via I-75 and SR 441.

Apr 18 – 25

G$21,618 GYD per night

Tiny home in Gainesville

4.92 out of 5 average rating, 104 reviews

Harmony Tiny House-NO Cleaning Fee

Beautifully built and decorated, Harmony Tiny house is located close to Newnan’s Lake but only a 10 minute drive to downtown. Surrounded by woods on 3 sides, it sits behind the main home on an acre of land with a small creek in the back. You have access to the back yard with an outdoor table and chairs and also a key to the utility room if you need to do a load of laundry. The sliding glass door entry faces the backyard. Please note that pets are allowed and there is a $30 pet fee.

Jun 5 – 12

G$16,620 GYD per night

Tiny home in Alachua

4.95 out of 5 average rating, 263 reviews

Ela's Tiny House: Springs, Trails & Disc Golf!

Ela's Tiny House is a 40ft Thomas School Bus converted into a unique and elegant experience! Nestled on 28 Acres of beautiful Florida nature, you can soak up the sun and unwind. Enjoy laying in a hammock and star gaze, catch a stunning sunrise or play a round of disc golf. Paddle board the Santa Fe River, swim with manatees @ Ichetucknee Springs, or soak in the cool waters @ Blue Springs. The Historic town of Alachua, High Springs and Gainesville all within a 20 min drive.

Sep 3 – 10

G$14,979 GYD per night

Cottage in Keystone Heights

4.84 out of 5 average rating, 192 reviews

"Love Shack"

Nice little country lake house with a quiet safe environment. The house is simple and meant as a getaway from the hustle of the city. There is lake access with a canoe and kayak available for your enjoyment. The home is small and not meant for a large Amount of people. The area offers a quiet "getaway". The home has three small bedrooms, kitchenette, 1.5 bathrooms, living room and a small dinning area looking at the lake. The hot tub is available with advance notice.

Mar 11 – 18

G$16,524 GYD per night

Cabin in High Springs

4.94 out of 5 average rating, 359 reviews

Getaway Gilchrist Springs - Orlando

An easy drive from the city, Getaway is a new way to experience the great outdoors. Nestled across dozens of acres of private woodlands, our modern, tiny cabins have everything you need (comfy bed, bathroom, fresh linens) and nothing you don’t. Featuring a private outdoor area (hello, fire pit), each cabin is designed to help you relax, unwind and disconnect from the everyday. Plus, as part of your stay, you'll receive firewood, a s'mores kit, coffee and bottled water*.

Apr 30 – May 7

G$28,639 GYD per night

Apartment in Waldo

4.99 out of 5 average rating, 148 reviews

Fernbank on beautiful Lake Alto. Laketime Getaway

Visit this beautiful, tranquil lakeside spot for an amazing getaway. It's a six acre property, an inspiring place to study, write, or get work done with fun things to do while on a break. Swim, kayak, canoe, paddle board or enjoy sitting on the dock. Visit the barn for basketball, ping pong, and corn hole. It's a studio apartment with a private bathroom and beds for four, plus two couches and air beds available. Note: This is an upstairs apartment.

Jun 18 – 25

G$22,336 GYD per night

Home in Citra

4.99 out of 5 average rating, 348 reviews

All About Horses

Our place is close to I 75 half way between Gainesville and Ocala and is good for couples, solo adventurers, and business travelers. Spend a week or weekend in a sunny Florida on a horse farm. We have a newly renovated, spacious modular home 30mins from Gainesville (home of the Florida Gators). This immaculate and charming residence is fully furnished with four bedrooms and a large living room on owners' 40-acre horse farm.

Jun 12 – 19

G$16,695 GYD per night

Vacation rentals for every style

Get the amount of space that is right for you

Hotels

Stylish accommodations and amenities

Unique stays

Spaces that are more than just a place to sleep

Homes

Comfortable places with all the essentials

Popular amenities for Lake Santa Fe vacation rentals

Free parking on premises

Air conditioning

Other great vacation rentals in Lake Santa Fe

Cottage in Melrose

4.91 out of 5 average rating, 148 reviews

Cozy Melrose Mermaid Cottage

Oct 5 – 12

G$14,520 GYD per night

Home in Fort McCoy

4.92 out of 5 average rating, 284 reviews

Salt Springs Soulful A-frame Retreat

Jul 12 – 19

G$28,434 GYD per night

Home in Fort McCoy

4.99 out of 5 average rating, 145 reviews

Lakefront Getaway Stay-Cation

Nov 26 – Dec 3

G$43,136 GYD per night

Tiny home in Fort White

4.96 out of 5 average rating, 351 reviews

Rum Island Cabin on Santa Fe River

Oct 11 – 18

G$21,693 GYD per night

Cabin in Fort McCoy

4.85 out of 5 average rating, 175 reviews

Camp Fox Den. A waterfront A-frame with a view.

Mar 3 – 10

G$17,001 GYD per night

Home in Alachua

4.82 out of 5 average rating, 197 reviews

Gated Golf Getaway close to Springs

Jun 14 – 21

G$29,442 GYD per night

Cottage in Morriston

4.85 out of 5 average rating, 179 reviews

Monarch Retreat (9 mil Blue Grotto) Dogs Welcome

Feb 23 – Mar 2

G$19,946 GYD per night

Guest suite in Palatka

4.84 out of 5 average rating, 200 reviews

❤️ Peaceful Rustic-Modern Lakeside Wooded Retreat ❤️

Nov 28 – Dec 5

G$25,149 GYD per night

Lake Santa Fe fishing house rentals

Home in Keystone Heights

4.93 out of 5 average rating, 163 reviews

HerringLake

Feb 24 – Mar 3

G$24,326 GYD per night

Home in Branford

4.98 out of 5 average rating, 124 reviews

The Suwannee River Rest & Adventures

Oct 18 – 25

G$51,396 GYD per night

Home in Astor

4.95 out of 5 average rating, 119 reviews

River house with 2 boat docks

Oct 1 – 8

G$40,828 GYD per night

Home in Jacksonville

4.9 out of 5 average rating, 109 reviews

*Waterfront Cottage* FAST WIfI. Come Work or Play!

May 21 – 28

G$30,382 GYD per night

Home in Jacksonville

4.99 out of 5 average rating, 189 reviews

Single House:4 beds/2baths/12guests/huge backyard

Mar 15 – 22

G$48,541 GYD per night

Home in Melrose

4.96 out of 5 average rating, 81 reviews

Sante Fe Lakehouse with Canal for your Boat

Mar 22 – 29

G$50,941 GYD per night

Home in Melrose

4.91 out of 5 average rating, 66 reviews

Three Bedroom House on Private Scenic Lake Mable

May 16 – 23

G$25,175 GYD per night

Home in Melrose

5.0 out of 5 average rating, 32 reviews

The Lily Pad-Enjoy Spring Days at the Lake!

Feb 24 – Mar 3

G$33,831 GYD per night

Other great vacation rentals in Lake Santa Fe

Cabin in Fort White

4.93 out of 5 average rating, 270 reviews

Log Cabin in Spring Country WiFi - TV

Mar 8 – 15

G$20,288 GYD per night

Cabin in Alachua

5.0 out of 5 average rating, 102 reviews

Rose Cottage at Alpaca Acres

Jan 19 – 26

G$17,432 GYD per night

Home in Gainesville

4.8 out of 5 average rating, 112 reviews

El Ranchito

Sep 22 – 29

G$21,185 GYD per night

Farm stay in Middleburg

4.93 out of 5 average rating, 177 reviews

A Private Loft at Grand Landings Equestrian Center

Sep 20 – 27

G$22,493 GYD per night

Guest suite in Gainesville

4.97 out of 5 average rating, 416 reviews

Private guest suite in a quiet modern farmhouse

Jul 26 – Aug 2

G$14,176 GYD per night

Cabin in La Crosse

4.91 out of 5 average rating, 129 reviews

Tiny Farmhouse on The Grove

Feb 3 – 10

G$23,444 GYD per night

Guesthouse in Gainesville

4.98 out of 5 average rating, 636 reviews

Unique Container "Caja Verde" 1 Mile UF & Downtown

Jun 26 – Jul 3

G$18,398 GYD per night

Tiny home in Alachua

4.84 out of 5 average rating, 240 reviews

Shiva Tiny Home ~ Outdoor waterfall shower

Jan 3 – 10

G$16,758 GYD per night

Destinations to explore