Panama Canal vacation rentals

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Top-rated vacation rentals in Panama Canal

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Condo in Panama

4.99 out of 5 average rating, 205 reviews

Patty’s Cozy & Quiet Studio with K-bed in Casco

*TOTALLY renovated on NOV 15th 2023: new floors, modern bathroom, new design & art work* Photos to come! Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen beside from the main living space. It is spacious, comfortable and tastefully decorated!

Jun 26 – Jul 3

G$20,510 GYD per night

Superhost

Home in Gamboa

4.86 out of 5 average rating, 88 reviews

BirdHouse@ Gamboa Panamá Canal

Explore the wonders of the Panama rainforest and return to our magical tropical home! This unique house and pool is a wonderful place to escape the hustle of Panama City, celebrate nature, and enjoy family and friends. Gamboa is a safe, quiet town embedded in the Soberania National Park; it is the entry point to Pipeline Road, some of the best birding in the world. Or take leave of the forest and watch manatee, while fishing for peacock bass in Gatun Lake or paddling kayaks up the Chagres River.

Aug 2 – 9

G$76,134 GYD per night

Guest favorite

Guesthouse in Gamboa

4.95 out of 5 average rating, 56 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Feb 8 – 15

G$18,124 GYD per night

Guest favorite

Apartment in Panamá

4.9 out of 5 average rating, 360 reviews

Chic Studio in Casco Antiguo - View to Main Plaza

Located in trendy Casco Antiguo, this studio apartment is walking distance of restaurants, cafes, supermarkets, pharmacies and the overall life of Casco. The building has recently been renovated and has a beautiful view of Plaza Catedral. Note: As seen on previous comments, there used to be a bar club in the rooftop and at the bottom of the building. Good news, there are no more bars in the building and the studio has soundproof doors as Casco is an area with the best nightlife in Panama.

Jun 6 – 13

G$17,256 GYD per night

Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 27 reviews

Amazing experience in Casco Viejo with ocean views

Disfruta la cultura panameña desde el centro de Casco Viejo, donde conocerás la arquitectura colonial, podrás visitar los mejores restaurantes, sitios nocturnos y rooftops característicos de la zona. Apartamento tranquilo y confortable. Cuenta con una cama queen, 1.5 baños, armario, aire acondicionado, cocina equipada, comedor, sala, acceso a WiFi de 500 mbps, espacio de trabajo, balcón y comedor al aire libre. ¡Te ofrecemos todo lo que necesitas para vivir la mejor experiencia local!

Mar 15 – 22

G$23,037 GYD per night

Guest favorite

Townhouse in Panamá

4.97 out of 5 average rating, 161 reviews

Casa Casco Amigos - The Only House in Casco.

Located by the French Embassy in Casco Viejo in the absolute safest and most prestigious area of Panama City, Casa Casco Amigos is a 3 level, 3 bedroom 351 square meter house with a roof terrace and a garden terrace which can sleep 9. Despite the liveliness of the area, there is no noise whatsoever in the bedrooms. Perfect for 1 or 2 families, or a group of 6 to 9 friends who want to be in the heart of the old city, with a sea view and many areas to lounge and avoid the midday heat.

Feb 22 – Mar 1

G$75,129 GYD per night

Guest favorite

Apartment in Panamá

4.95 out of 5 average rating, 154 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Jul 3 – 10

G$36,765 GYD per night

Guest favorite

Apartment in Panamá

4.97 out of 5 average rating, 130 reviews

Angie’s Place Cozy n Comfy in the ❤️ of #CascoViejo

Remodelado, cómodo y céntrico en el corazón de Casco Viejo, pintoresco lugar declarado Patrimonio de la Humanidad por la UNESCO. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. La propiedad data del siglo XVII (1756) historia y buen ambiente. Podrás explorar la zona a pie, cocina full equipada, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar-Smart tv -Cocina full equipada -1.5 baños Policía de turismo 24/7

Sep 13 – 20

G$22,176 GYD per night

Guest favorite

Loft in Panamá

4.92 out of 5 average rating, 177 reviews

Amazing Loft with the Best view of Casco viejo!

Hermoso loft ubicado en el centro de Casco Antiguo, la zona más turística de Panamá. Ven, disfruta y relájate en este impresionante loft, con una vista increíble de la Catedral de Panamá. Puedes visitar museos, bares, restaurantes e iglesias ubicados a tan solo unos cuantos metros de distancia. Beatiful Loft located in the center of Casco Antiguo, Panama´s most turistic location. Come, enjoy and relax at this amazing loft, with amazing view to Panama´s Cathedral.

Apr 11 – 18

G$23,617 GYD per night

Guest favorite

Apartment in Panamá

4.85 out of 5 average rating, 231 reviews

Pool and rooftop with Two Bedrooms and Kitchen A8

Unique architecture in Casco Viejo, entirely renovated very recently. You have a pool, a rooftop, and your completely private and brand new room. Double bed, designer furniture, tv with Netflix, air conditioning, sheets and towels, shampoo, soap, etc. The building with more history of Casco Viejo, given its name after the first president of the republic in 1903, Tomas Arias, who lived here. The accommodation consists of: - Room No.

Jul 2 – 9

G$27,222 GYD per night

Guest favorite

Guest suite in Gamboa

4.95 out of 5 average rating, 78 reviews

Beautiful annex in the middle of Gamboa Rainforest

Enjoy nature without leaving home in this historic town located in Parque Soberania and on the shores of the Panama Canal. Just 40 minutes from the stressful capital, you can relax walking, bird watching in Pipeline, kayaking, fishing on the Chagres River, on the island of monkeys, visiting an indigenous town or watching sloths. Also bike lovers will find their place. At night, take a relaxing bath and sleep peacefully.

Mar 25 – Apr 1

G$15,119 GYD per night

Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 20 reviews

Tropicool Loft w/rooftop steps from Casco

This loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftop bars, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fiber optic internet, and great AC to keep the place cool.

Apr 9 – 16

G$21,198 GYD per night