Vacation rentals in Pike County

Little House in the Hollow

Enjoy a private peaceful setting that is Conveniently located. Large fenced in yard for the kids and/or pets. Also has a 4 person hotub which is available year-round. The house is fully stocked for convenience. The house also has covered parking, outdoor fire pit, BBQ grill a play place for the kids and more. You will be within walking distance of 2 National Landmarks (Mark Twain Cave, Cameron Cave) as well as our Winery and Giftshop. Located just two miles from Hannibal's Historic District.

Beautiful Secluded Home With a breathtaking view

Long hidden driveway up to the ultimate private getaway. Beautiful house on six acres with panoramic views of the Illinois River valley, and plenty of space inside and out. Wake up to a breathtaking sunrise from the deck, and feel the serenity as the barges pass by. As evening comes to a close, enjoy a drink and some s’mores by the fire pit and take in the tranquility of this country setting. Seriously, do yourself a favor and spend some time at this quiet, peaceful, one of a kind property!

Genevieve’s Federal House

This home is a fully restored 1 story Federal house, which you will have full access to. It is located close to the Mark Twain Boyhood Home, and right off Broadway. The house comes furnished with seating, furniture, and 2 Roku televisions. There are two bedrooms, one bathroom, a dining room, living room, and a kitchen. The home has central air conditioning and heating, washer and dryer, dishwasher, and a beautiful clawfoot cast-iron tub with shower. There is off street parking.

Florence Guest House

This 1,200 sq. ft. PRIVATE BOOK is a 175 year old building that Abe Lincoln stayed in. Central A/C, Forced air heat, Two decks (one overlooking the Illinois River), burn pit, outside grill, fully equipped kitchen, screened in porch, ample parking, access to the Illinois River/ boat ramp near, tie up on Our Private Lots! NOTE: RECENTLY HAD Guests' wanting to "JUST GET AWAY" for A Time!!! PRIVATE TIME ALONE, Guaranteed!!! NEW KEURIG; BRING YOUR OWN K-CUPS!!!***

The Yellow Rose Historic Home

This cozy home is 8 blocks to the Mississippi. Beautiful overlooks, nice restaurants, historic homes. A short drive to Two Rivers Marina, the SLU Lay Center Sculpture Park, Hopewell Winery, Ted Shanks Conservation Area, Clarksville Apple Shed. 30 min. to Hannibal, MO - home of Mark Twain. 45 min. to Mark Twain Lake. 90 min. to St Louis. Plenty of sight-seeing, hunting, fishing, boating in the area. Fur babies are welcome.

Pilot House

Enjoy nostalgic downtown Hannibal. Located on Main Street providing walking access to a movie theater, the riverfront, restaurants, bars, shopping, museums, and historic Mark Twain sites. Two private bedrooms—one with a king bed and one with a queen— each with flat screen televisions. This unique apartment has a living area with additional daybed, eat-in kitchen that seats 6, and a cozy area for a family game night.

Dome View Loft

Dome View Loft is a unique unit with comfort and spacious for your group. There is two bedrooms with each offering a queen bed. We own a Cafe with full menu right below for your convenience. There is a washer and dryer if needed. The view of our historic Courthouse is beautiful. Come and enjoy the quiet atmosphere with free parking. This location is within walking distance for downtown coffee shops and Book Store.

The View on Reservoir

Relax and unwind in this tiny, remodeled home with great views! Located 2 minutes from downtown and overlooking the Mississippi River, this cozy, tranquil house is the perfect getaway to America’s hometown. This one bedroom home is the perfect place to stay whether you want to get out and enjoy everything Hannibal has to offer or kick back on the deck overlooking the Mississippi!

The Milkhouse

Get away from it all when you stay under the stars, commune with the cows and observe wildlife. See a working ranch and learn about farm life from us. Stay in a climate controlled modern farm house with lots of extras. Highway access and solid driveway to the farm house. Explore the hills, hollers and creeks. Close to Hannibal Mo and Mark Twain Lake among other local attractions.

Hucks Modern Hideaway

Huck's Modern Hideaway is a perfect space for a quick to Hannibal, MO! Completely refreshed efficiency suite 5 minutes from The Mighty Mississippi River and beautiful downtown Hannibal, MO. Come and enjoy a convenient space when you are in town for The Mark Twain, Tom Sawyer, Big River Steampunk, or any of the other festivals that might bring you to town.

The Rose Cottage in historic downtown Hannibal

Located at the tip of historic Main Street in downtown Hannibal and within easy walking distance of many Mark Twain attractions, restaurants, pubs, shopping, entertainment, etc. At the Rose Cottage, we strive to provide guests with a high quality stay in a cozy, relaxing environment where they can easily enjoy all that downtown Hannibal has to offer.

Full Country Home Pittsfield, Illinois

Relax with the whole family at this peaceful place to stay. WE HAVE WIFI and Smart Tv in the living room and back bedroom Great place for hunters,jeepers,rock climbers, 10 minutes to Pittsfield,Illinois where there are many restaurants, shopping and historic attractions. Located between New Hartford and Summer Hill, Illinois on US Hwy 54