House vacation rentals in Panhandle

Find and book unique houses on Airbnb

Top-rated house rentals in Panhandle

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A charming white house is depicted against a colorful sunset sky. The entrance is highlighted by a yellow door, welcoming guests. A small seating area is visible on the front porch, with a gravel driveway leading to a black garage door on the left.
Home in Amarillo
4.91 out of 5 average rating, 220 reviews

Right by Cadillac Ranch | Cool, Clean, Convenient!

✹ PRIME LOCATION –We are the closest Airbnb to Cadillac Ranch — just a 30-second drive on the same road. We are just off I-40 !!!Strict No Smoking Policy!! NOT ALLOWED!! ✹ 2 bedrooms w/ a KING SIZE BED Nightlights closets & Netflix TVs in each room ✹ Private 5-acre lot for peace & quiet ✹ Central heat & A/C + super fast WiFi ✹ 3 miles to Soncy Rd – top dining & shopping ✹ 6 miles to Cinergy – movies, arcade & more ✹ Proud neighbor of Loves Travel Stop – grab a snack, fuel up, an hit the road.

Top guest favorite
A bright studio space is showcased, featuring a spacious bed with white bedding. Comfy brown chairs are placed nearby, and a well-equipped kitchen is visible in the background. A wooden dining table with chairs is situated to the right, enhancing the overall layout.
Home in Amarillo
4.99 out of 5 average rating, 561 reviews

The Bunny Bungalow

Enjoy a relaxing getaway for two in our brand new bungalow. The studio design features everything you need in one convenient living space - a king bed with fresh white cotton bedding and luxe pillows, comfy chairs for enjoying the fireplace and TV, intimate dining area and a stylish kitchen. The bath features a double vanity, tub for two and modern shower. A full size laundry set is tucked near the back door. The back yard features a cedar pergola with hot tub, a seating area and gas BBQ grill.

Superhost
A game room features a solid wood shuffleboard table, highlighted by ten black bowling pins arranged at one end. Soft blue lighting enhances the space, complementing the modern decor with framed images on the walls and a television visible in the background.
Home in Amarillo
4.88 out of 5 average rating, 160 reviews

Magnificent Home, Game-room, Close to Everything

This ideally located private home is located in one of the newer developments in southwest Amarillo. This modern, stylish home is a 2-min drive to the Loop & easy access to I-27—taking you to the downtown district, dining, Hodgetown & the Civic Center. Head South you’re just minutes from Canyon, WT A&M University & Palo Duro Canyon. Plenty to do are only minutes away. This convenient home is ideal whether passing through town or better for longer stays with amenities that feel like home.

Top guest favorite
A newly built house features a modern design with a welcoming entrance. Two rocking chairs are positioned on the front porch, accompanied by a potted plant. The exterior is white with dark trim, complementing the wide open landscape and clear blue sky in the background.
Home in Amarillo
4.98 out of 5 average rating, 257 reviews

The Longhorn Lodge

This awesome little house is just 10 minutes from most of Amarillo. This house is very clean and newly built in 2024. Our guests all agree this is such a relaxing place to stay. The house itself is a small 1 bedroom, with everything you'll need for your stay. Inside the house is very clean and comfortable but outside is my favorite part. Here you'll find some of the best front porch sittin' around and the sunsets are pretty awesome too! You'll have wide open spaces and plenty of privacy.

Guest favorite
The exterior of the home showcases a combination of brick and stone design, featuring a unique turret and several large windows. A well-manicured lawn surrounds the structure, with a pathway leading up to the entrance. The sky displays a gentle blue hue.
Home in Amarillo
4.91 out of 5 average rating, 244 reviews

The Castle-Family Friendly-Spacious-Large Parking

Come and enjoy this gorgeous home!🏡 Great for 🚗TRAVELING groups, or 🧑‍🧑‍🧒‍🧒 LARGE families! Peaceful neighborhood, with ☕️COFFEE SHOP, ⛽️GAS STATION, and 🍗DINNING across the street! Easy access to I-27, and a short drive to I-40. 4 BEDROOMS, and 3 full BATHROOMS! Beautiful primary bedroom, restroom , and walk-in close. Great for getting ready! 🏋️‍♀️There is a home gym with cable machine, squat rack, bench, plates and dumbbells! Great outdoor area for hanging out and grilling.

Top guest favorite
The living area features a soft-toned couch and armchair, complemented by a wooden coffee table atop a patterned rug. A large television is mounted on a white entertainment unit. Light floods the room from multiple entrances, creating a bright and inviting space.
Home in Canyon
4.96 out of 5 average rating, 129 reviews

Chateau Bliss: Stylish Stay w/ HOT TUB

Escape to this spacious 3-bed, 3-bath retreat in Canyon, TX, featuring 2 king beds and 1 queen bed, just minutes from Palo Duro Canyon & WT. In the evenings you can relax in the hot tub! *5 Mins to Downtown and WT *10 Mins to Palo Duro Canyon *10 Mins to Maxwell's Pumpkin Farm *20 Mins to Hodgetown Stadium *30 Mins to Cadillac Ranch + Big Texan + Wonderland *Work From Home At Your Desk With Fast Wifi *Fully Equipped Kitchen *Bonus Outdoor TV + Hot Tub *Self Check-in

Superhost
A spacious bed is positioned against a neutral wall, complemented by two stylish bedside lamps. Decorative pillows add a touch of elegance. Light fills the room through a large window, which is framed by simple curtains, creating a bright and serene atmosphere.
Home in Amarillo
4.86 out of 5 average rating, 157 reviews

The Cottage On Tyler

Keep it simple at our peaceful and centrally-located in the heart of historic Downtown Amarillo. Our spacious & newly renovated 3 bedroom cottage is within walking distance from favorite local restaurants, bars & coffee shops. Our enclosed back patio provides for a cozy back porch gathering among family & friends. We are pet friendly & love our furry friends!

Guest favorite
Home in Canyon
4.91 out of 5 average rating, 227 reviews

Clean, Spacious, Pet Friendly, X2 Living room

Whether you're seeking adventure, relaxation, or simply a peaceful family recharging retreat this breathtaking home is the perfect place to escape the hustle and bustle of everyday life! Immersing yourself in the stunning beauty of Palo Duro Canyon, our luxurious amenities, and the beauty of having nature at your doorstep, it's a vacation you'll never forget.

Top guest favorite
An overview of six luxury cabins is presented, arranged in a row with a scenic canyon backdrop. Each cabin features modern architecture with wooden exteriors and large windows. The landscape showcases rugged terrain and vibrant hues, enhancing the natural beauty of the location.
Home in Canyon
4.99 out of 5 average rating, 216 reviews

Rustic Gorge | Best Views of Palo Duro Canyon

Rustic Gorge in Rustic Luxury Camp offers an unmatched experience with our six tiny luxury cabins, providing spectacular views and a unique stay right on the edge of the second largest canyon in the US. Each cabin is meticulously designed to blend seamlessly with the natural beauty of the surroundings while offering luxurious comfort.

Top guest favorite
Home in Amarillo
4.89 out of 5 average rating, 119 reviews

1-800 We got the stay

Your family will be close to everything when you stay at this centrally-located place. 5 minutes from the Amarillo Civc Center & Downtown Amarillo. 10 minutes from Starlight Ranch. 2 minutes from trade winds airport. 15 minutes from Rick Husband International Airport. 3 miles off I40 and 2 miles off I27.

Top guest favorite
A decorative fountain is featured in the foreground, with water gently cascading from its spout into a small pool. A white bench sits nearby, framed by lush green trees. In the background, a grassy area is visible, with houses peeking through the foliage.
Home in Amarillo
4.94 out of 5 average rating, 152 reviews

Park Place

The whole group, including well-behaved house-trained pets, will enjoy easy access to everything from this centrally located place located on a quaint neighborhood park in an historic neighborhood with brick streets. The Place is decorated with hand-painted artwork by the host.

Top guest favorite
A remodeled one-story home features a gray exterior with white trim. A welcoming front porch is accentuated by a white railing. A wheel decoration is positioned against the ground, and a concrete pathway leads to the entrance. Natural light enhances the inviting appearance.
Home in Amarillo
4.96 out of 5 average rating, 267 reviews

Cozy Amarillo Abode

Completely remodeled cozy two-bedroom home! Located just off I-40 with easy access to dinning and shopping. Short drive to Amarillo's medical district or Downtown area. Equipped with all new kitchen appliances and has washer and dryer available. Has a great homey feel!

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