
Guesthouse vacation rentals in Orange County
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Top-rated guesthouse rentals in Orange County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Orange County guesthouse rentals
Family-friendly guest house rentals

Cute Downtown Carrboro Studio Cottage

Urban homesteading in Carrboro

The Store in Hobo, a reader/writer’s retreat.

Cozy Cottage on a Hilltop

Separate In-Law Suite in Carrboro

Soul Retreat in the Heart of Carrboro

CFCB cabin retreat minutes from Duke, NCCU, & UNC

Charming Cabin with Private Wooded Pond
Guest house rentals with a patio

"Wit's End" welcomes you! 2BR comfy guest house

Carolina Cottage

Duke Forest Hideaway

Cozy Sauna Retreat - Woodland Guesthouse

Sleek Renovated Studio Just (2).Downtown Durham

“Meelie Doll”~ Private - Cozy Stdio Apt abv garage

Guesthouse in the heart of South Durham

New Apt- walk to everything Rockwood
Guest house rentals with a washer and dryer

Sunset Studio near Downtown Fuquay Varina

Guest House on the Cary Downtown Park!

Central to Everything, Renovated, Dog Friendly.

The Sacred Cedar

Duplex filled with natural light

Private 'Barn'dominium with No Cleaning Fee!

Boarding House

Garden House in Old North Durham
Destinations to explore
- Cabin rentals Orange County
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- Rentals with a fireplace Orange County
- Rentals with a hot tub Orange County
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- Rentals with lake access Orange County
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- PNC Arena
- Duke University
- Wet'n Wild Emerald Pointe Water Park
- North Carolina Zoo
- Durham Bulls Athletic Park
- Tobacco Road Golf Club
- Raven Rock State Park
- Sedgefield Country Club
- Frankie's Fun Park
- Greensboro Science Center
- Sarah P. Duke Gardens
- American Tobacco Campus
- Lake Johnson Park
- William B. Umstead State Park
- Starmount Forest Country Club
- North Carolina Museum of Art
- North Carolina Museum of Natural Sciences
- North Carolina Museum of History
- Eno River State Park
- Carolina Theatre
- International Civil Rights Center & Museum
- Durham Farmers' Market
- Gregg Museum of Art & Design
- Gillespie Golf Course