Hotel vacation rentals near Moscone Center

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Top-rated hotel rentals near Moscone Center

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Guest favorite
Hotel room in South of Market

Walk to Union Square + On-site Dining & Gym

Experience refined urban luxury at Hyatt Regency San Francisco Downtown SOMA, ideally located steps from SFMOMA, Moscone Center, and Union Square. Perfect for art lovers and city explorers, this premier hotel features oversized, light-filled rooms with breathtaking city views. Enjoy exceptional on-site dining at La Societe Bar & Brasserie, a state-of-the-art 3,200 sq. ft. fitness center, pet-friendly accommodations, and seamless access to San Francisco’s finest shopping, dining, and transit.

4.93 out of 5 average rating, 123 reviews
Guest favorite
The living area is characterized by a neutral color scheme with a cozy sofa and an armchair, complemented by decorative pillows. A contemporary coffee table is centered on a textured rug, while a mounted television and a painting are displayed on the walls. Natural light enters through the large windows.
Hotel room in Nob Hill

Nob Hill Inn 2 Bd / 2 Ba Apartment

Experience luxury at the Nob Hill Inn in this expansive apartment perfect for groups seeking a home away from home. The apartment features two inviting bedrooms with a king-sized bed and a queen-sized bed, and 2 separate bathrooms. The well-appointed living area boasts a fully-equipped kitchenette with all the appliances you need to cook and entertain with ease. We have three equivalent apartments with slight differences. The pictures show a combination of these apts and the hotel lobby.

4.93 out of 5 average rating, 68 reviews
Superhost
The exterior view of The Marker showcases its Beaux-Arts architecture with elegant detailing. Multiple stories feature large windows, illuminated at dusk, creating a welcoming ambiance. The building is framed by trees and streetlights, set against a softly lit sky.
Hotel room in San Francisco

Union Square Steps Away | On-Site Dining + Gym

Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24-hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

4.89 out of 5 average rating, 383 reviews
The exterior of the Wyndham Canterbury is presented, featuring a six-story building with a light-colored facade. The hotel sign is prominently displayed, and trees line the street, enhancing the urban atmosphere of the surrounding area.
Hotel room in San Francisco

Club Wyndham Canterbury One-Bedroom Suite

This spacious one-bedroom resort suite measures approximately 520 square feet. You will enjoy a queen bed in the master bedroom and a sofa sleeper in the living area. Additional amenities include a kitchenette and dining area. Maximum occupancy is four. Private sleeping area sleeps two.

4.89 out of 5 average rating, 132 reviews
Hotel room in South of Market

Hotel Zelos San Francisco, King room

A king room invites you into a sophisticated San Francisco urban retreat designed to impress. We offer pillow-top mattress, complimentary high-speed internet, flat-screen TV, work desk with lamp, bathtub, minibar, and an en suite bathroom with upgraded amenities.

4.83 out of 5 average rating, 719 reviews
Superhost
A spacious room features a queen bed with crisp white bedding, a flat-screen TV, and custom-designed furniture. A blue accent chair and small side table enhance the sitting area. The bathroom entrance is visible, indicating convenient access from the room.
Hotel room in Nob Hill

Restless City | Cable Cars Tours. Historic Sites

While our views are amazing, it’s the city’s energy and restless spirit of transformation that quickens your heartbeat and gets your mind spinning. At Stanford Court Hotel, we’ve crafted an experience that plays off this buzzing atmosphere.

4.85 out of 5 average rating, 127 reviews
Hotel room in San Francisco

Hotel Julian, Superior queen room

Perfect for shared stays, this room features two queen beds, refined modern design, and a sleek desk for work or leisure. Stay effortlessly connected with seamless Wi-Fi and enjoy a stylish, comfortable retreat for friends or family.

4.74 out of 5 average rating, 334 reviews
Hotel room in South of Market

Deluxe king room

Deluxe king room features a king bed with pillow-top mattress, plush chair and ottoman, walk-in shower, oversized desk, in-room safe, iron, air conditioning, and wifi. Pet-friendly, non-smoking, with wheelchair-accessible vanity.

4.75 out of 5 average rating, 1008 reviews
Hotel room in Downtown / Union Square

Queen Room

- Central location near Union Square. - Beautifully decorated rooms rock Japanese-inspired style, plush pillowtop beds and flat-screen TVs. - Other perks include an onsite car rental joint and a dog run (to name a few).

4.88 out of 5 average rating, 116 reviews
Superhost
A spacious room is furnished with a king bed dressed in crisp white linens and a blue accent throw. Natural light fills the room through a large window with a city view. A small sitting area includes a plush chair and a desk beside a bowl of fresh fruit.
Hotel room in Fishermans Wharf

Relaxed Vibes | Alcatraz | Picnic

Hotel Caza is a family-friendly hotel in the heart of historic Fisherman’s Wharf that embodies the spirit of California and is full of fun, warmth, and special extras to enhance your vacation experience.

4.69 out of 5 average rating, 108 reviews
Hotel room in Haight Ashbury

Stanyan Park Hotel, Selected by hotel

Room will be assigned at check-in based on availability. All rooms offer comfortable accommodations with standard amenities and have a maximum occupancy of 2 guests. Specific features may vary by room.

4.78 out of 5 average rating, 153 reviews
Hotel room in Nob Hill

Stanford Court San Francisco, Selected by hotel

Room will be assigned at check-in based on availability. All rooms offer comfortable accommodations with standard amenities and have a maximum occupancy of 2 guests. Specific features may vary by room.

4.73 out of 5 average rating, 191 reviews

Popular amenities for hotel rentals near Moscone Center

Quick stats about hotel rentals near Moscone Center

  • Total vacation rentals

    Explore 720 vacation rentals in Moscone Center

  • Nightly prices starting at

    Moscone Center vacation rentals start at G$6,276 GYD per night before taxes and fees

  • Verified guest reviews

    Over 13,540 verified reviews to help you choose

  • Family-friendly vacation rentals

    110 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 170 rentals that welcome pets

  • Vacation rentals with a pool

    70 properties feature pools

  • Rentals with dedicated workspaces

    450 properties have a dedicated workspace

  • Wi-Fi availability

    710 of Moscone Center vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Moscone Center rentals

  • 4.6 Average rating

    Moscone Center stays receive an average rating of 4.6 out of 5 from guests