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Vacation rentals in Middlesex County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Middlesex County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost
A cozy guest suite features a four-poster bed adorned with decorative pillows. A comfortable couch with patterned cushions is positioned beside a large area rug. A mounted TV is visible on the wall, and natural light fills the room through a window dressed with light curtains.
Guest suite in St. Thomas
4.76 out of 5 average rating, 71 reviews

Our Country Hideaway

Our cosy guest suite & all its charm will win you over! A boutique style room with a full bathroom with tub, walk in closet, mini fridge, microwave, Keurig, 65” TV, toaster oven, electric fireplace & heated floors. Soak in our hot tub or enjoy the nature views of deer and star filled night sky’s. The sunsets are beautiful it’s the perfect place to come relax & enjoy the peace. 15 min away from Port Stanley beach, 2 min from St. Thomas & 15 min from London. Central location off the beaten path.

Guest favorite
Farm stay in Strathroy
4.94 out of 5 average rating, 36 reviews

Unique off-grid cabin nestled in the woods

Sleep in a glass greenhouse under the stars. The Starhouse is a unique stay tucked into a quiet forest on our working organic farm. Discover a place to slow down, wake to birdsong, and experience some magic. Spend your mornings with coffee in the sunlight, your evenings by the fire, and your days wandering the gardens, meeting the chickens, and gathering food from our farm for dinner under the open sky. This is a simple, off-grid experience that is grounding and deeply connected to nature.

Guest favorite
The exterior view showcases a two-story home with a combination of brick and stone accents. A well-maintained driveway leads to a parked vehicle, while large, arched windows allow natural light to brighten the entrance. The front porch features elegant columns, contributing to the home's welcoming appearance.
Guest suite in London
4.92 out of 5 average rating, 267 reviews

Modern Cozy Executive Suite with Private Entrance

Forget your worries in this spacious and serene space. Welcome to our cozy centrally located basement unit with a separate private entrance. This place is just 2-5 minutes away from walmart supercentre, No Frills Grocery, Winners, Homesense, Marshalls, the University Teaching Hosipital, the University of Western Ontario and many other places. The stylish unit is perfect for working individuals, and people seeking a comfortable private and convenient stay in a beautiful neighborhood.

Top guest favorite
An open-concept living space features natural wood beams and a striking black accent wall. A round dining table is surrounded by four chairs, with a cozy seating area enhanced by a large beanbag. Decorative plants and stylish lighting fixtures add warmth to the environment.
Guesthouse in London
5 out of 5 average rating, 47 reviews

Stylish Private Loft | 1800s Farmhouse | Lake View

One-of-a-kind loft that sits inside a restored 1800s farmhouse with exposed beams, gas fireplace, and a sunroom with serene water view. Separate entrance, completely private unit — designed for the ideal getaway. King Endy bed with luxe cotton bedding, roomy bathroom with soaker tub. Nespresso, craft teas, induction stove. Hi-fi sound system, 55" 4K TV with Netflix and Prime. Sit/stand desk with Herman Miller chair. Minutes from the highway — peaceful, private, and unforgettable.

Superhost
A modern living area is highlighted by a spacious grey sectional sofa facing a wall-mounted television. Large windows create an airy ambiance, allowing natural light to fill the room, while a stylish electric fireplace offers a cozy focal point. The open design enhances the sense of space.
Home in London
4.85 out of 5 average rating, 72 reviews

Luxury 5BR· Chef's Kitchen · Sleeps 10 · Superhost

⭐ 4.85/5 · Verified Reviews · Superhost · 100% Response Rate New build, 2024 · 3,500 sq ft of designer luxury for up to 10 guests · London, Ontarios finest estate home in prestigious Silver Leaf Estates. Whether you're planning a family reunion, corporate retreat, graduation celebration, golf getaway, or Western University visit — this is the only home in London, Ontario that delivers resort-calibre space, finishes, and hospitality at an Airbnb. .

Top guest favorite
The kitchenette offers modern appliances, including a refrigerator and dishwasher, and features a long bar with three stools. A foosball table is positioned nearby, while large windows with horizontal blinds provide ample natural light.
Guest suite in London
4.91 out of 5 average rating, 216 reviews

West London Retreat with Hot Tub

Welcome to our retreat in west London! This stylish Two-Level Basement Split is a guest suite ideal for friends and families. Our 1+Den has 2 comfy Queen Beds, 1.5 bathrooms, a large kitchenette with every appliance you need, and a foosball table for some competitive fun. Outside, there's a hot tub, firepit (BYO wood), BBQ, and outdoor eating area. We live upstairs and are available to assist with the indoor or outdoor amenities at any time!

Guest favorite
The entrance to the home is framed by two brick walls, featuring large windows above the door. A small set of steps leads to a covered porch adorned with greenery and a potted plant, enhancing the welcoming atmosphere.
Home in London
4.96 out of 5 average rating, 52 reviews

Cozy London Home | Sleeps 8 | Lush Backyard

Welcome to your perfect home away from home in North London’s premier neighborhood—Foxfield! This beautifully maintained 2-storey gem offers the ideal blend of comfort, style, and space for your next getaway Whether you're traveling with family, friends, or a work crew, you'll love the roomy layout and thoughtful design of this home. With 3 large bedrooms and 2.5 sparkling bathrooms, everyone gets their own space to unwind

Top guest favorite
A modern studio space features a spacious bed with crisp linens and decorative pillows. A comfortable armchair sits next to a stylish wooden media console, housing a large television. Natural light fills the room through windows, with contemporary artwork adorning the walls.
Apartment in Strathroy
4.98 out of 5 average rating, 135 reviews

Strathroy Studio “Boutique living at its best!”

Welcome to your boutique-style studio in Strathroy — spotless, stylish, and thoughtfully stocked for a stress-free stay. Enjoy a 65" smart TV, fast Wi-Fi, a well-equipped kitchenette with coffee, tea & snacks, and a spa-clean bathroom with fresh towels. With private entry, easy parking, and cozy touches like slippers and local tips, it’s the perfect spot to unwind, work remotely, or explore the area in comfort.

Top guest favorite
A hot tub is situated on a spacious deck surrounded by lush green trees, providing a serene forest backdrop. Nearby, a glass-top table with several chairs offers an inviting space for outdoor dining. Sunlight filters through the leaves, creating a calming atmosphere.
Home in Southwold
4.97 out of 5 average rating, 205 reviews

Nature Lover's Luxury Paradise

Nature Lover's Luxury Home in the woods. Creek's Edge Estate is a beautifully decorated home that is nestled on 10 acres of private woods. Minutes from London, ON this 4BDRM+3.5 BATH home sits next to some private hiking trails. Enjoy the sounds & sights of nature while relaxing in the hot tub. A beautiful escape for couples, families or groups looking to relax and recharge. Too many amazing amenities to list!

Guest favorite
The living area contains a comfortable sofa and two green armchairs, with a wooden coffee table in the center. A television sits atop a white entertainment unit, and large windows provide a view of nature outside. Light curtains create a bright and airy atmosphere.
Apartment in London
4.92 out of 5 average rating, 221 reviews

Riverfront Retreat Near Downtown

Welcome to our inviting 1-bedroom, 1-bathroom apartment retreat near downtown! Featuring a private balcony overlooking the Thames river and a beautiful trail directly behind the house. All amenities, wifi, laundry, and Netflix included. Enjoy the convenience of being near downtown London. 10-15 minute walk to Budweiser Gardens, Downtown, and a 5 minute drive to Western University.

Top guest favorite
A modern one-story unit is shown with a gray exterior and a white door. Large windows permit light into the space, enhancing the exterior's simple design. A neatly maintained garden surrounds the unit, adding greenery and a cozy atmosphere.
Guesthouse in London
4.96 out of 5 average rating, 140 reviews

Argyle Garden Suite: Patio and Garden areas

Welcome to the Argyle Garden suite. Located in historic east London, this sleek, modern newly constructed 1 bedroom unit was made with your comfort in mind. Rest easy in the queen-sized bed in the main bedroom overlooking the secret garden accessible by path on left of unit. The queen-sized pull-out sofa in the living room makes it perfect for families or up to 2 couples.

Guest favorite
A comfortable living area features a spacious gray sectional sofa, accompanied by a glass coffee table. A wall-mounted smart TV is visible, and a small kitchenette area is located in the background. The room is brightened by soft lighting and neutral wall colors.
Home in London
4.85 out of 5 average rating, 259 reviews

Vikkyjas Garden

Welcome to your cozy oasis! Nestled in a beautiful basement, our one-bedroom retreat offers a private entrance, a sumptuous Queen Size bed, and unparalleled privacy. Situated near Argyle shopping mall, parks, and eateries, with Fanshawe college just a 7-minute drive away, enjoy the perfect blend of urban convenience and natural tranquility right at your doorstep.

Popular amenities for Middlesex County vacation rentals

  1. Airbnb
  2. Canada
  3. Ontario
  4. Middlesex County