Vacation rentals in Mesa, Phoenix

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mesa, Phoenix

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

A modern bedroom features a spacious bed adorned with a gray quilt and a bright yellow throw. Two artworks are hung on the walls, while large windows allow natural light to illuminate the room. A desk and chair are positioned nearby, adding functionality.

Home in Camelback East

4.98 out of 5 average rating, 802 reviews

Luxe Bedroom in Resort setting @ Villa Paradiso

Take a swim while steeped in the lush environs of the garden patio at this chic B&B. Enjoy the included continental breakfast in the shared, gourmet kitchen to serve at a luxe hardwood table amid exposed brick, large picture windows, and vibrant artwork and decor. * New private & modern bedroom with private bath. * Newly renovated 3-bedroom mid-century home with private swimming pool & lush landscaping. * This B&B listing includes continental breakfast we set up daily in the shared gourmet kitchen. Our house is a mid-century modern property designed and built in 1970 by a Phoenix Wrightsian architect and fully remodeled in 2015. Its central location is a perfect setting if you're exploring Phoenix for pleasure, visiting for an event or spending time in town on business. Full, shared access to all pictured spaces for this "Entire Home" listing. We occupy one end of the house and have two active listings for guests at the opposite end of house. Look for us online: #VillaParadisoPhoenix Enjoy the kitchen space and help yourself to breakfast. Your favorite steamed coffee beverage, hot tea and continental breakfast (yogurt, juice, croissants, fruit, etc.) are all included with your listing. Enjoy all pictured spaces indoors and outdoors. Your room and bathroom are private with a queen bed, premium linens, a closet, Wi-Fi, Netflix, a desk and more. The bathroom is just a three steps from the room and we provide bathrobes for your convenience. You are welcome to the kitchen & fridge, private swimming pool, the front and back patios and all other living spaces. The front door is equipped with smart lock you may open with your smartphone. We live in the house and enjoy whatever level of interaction our guests choose. The home is in a quiet and well-established residential neighborhood on the border of Phoenix and Scottsdale and is within driving distance to nightlife spots, restaurants, hiking, and sporting event locations. Depending on the length of your stay and the places you intend to visit, a rental car or Uber service may be the best choices. Just feel free to ask us. Smartphone navigation will guide you to our address easily and with accuracy. We are less than 10 mins from the airport. Our house is pet-free and we are non smokers.

Top guest favorite

A spacious driveway is shown, featuring a parked car on the left and a paved path leading toward a white guest house. Lush greenery is visible with several trees and shrubs, creating a peaceful outdoor setting.

Guesthouse in Paradise Valley Village

4.95 out of 5 average rating, 172 reviews

Clean and Cozy Guest Home

MESSAGE US IF YOU ARE LOOKING FOR A 3+DAY STAY IF DAYS APPEAR UNAVAILABLE! We are located in Northeast Phoenix in a safe quiet family neighborhood. We are 1/2 mile from the 51 and 101, less than 10 min from PV restaurants, & 20 min away from Sky Harbor Airport. Private guest house can accommodate 6 guests with 2 bedrooms with 1 Queen bed each, 1 Queen sleeper sofa in living room, 1 bathroom, and full kitchen. There are TVs in the common area as well as one bedroom. NO PETS,NO PARTIES,NO SMOKING

Top guest favorite

A bright living room features comfortable seating, including a dark sofa and armchair, arranged around a central coffee table. A large flat-screen TV is mounted on the wall, while a patterned area rug is laid on the tiled floor. Natural light enters through sliding glass doors.

Home in Paradise Valley Village

4.97 out of 5 average rating, 102 reviews

Family Oasis with Mountain Views, Heated Pool*

Be our guest at this family-friendly 3 bed, 2 bath pool home nestled in a beautiful, quiet neighborhood just 0.6 miles from the hiking trails of the Phoenix Mountain Preserve. Optional nightly rate applies for pool heat* Located in the heart of Phoenix near shops and eateries, easy freeway access, less than 20 mins from the airport. Whatever your plans in the Valley of the Sun and Scottsdale include, you'll only be a short drive away. Backyard remodel coming Summer 2026! Permit STR-2025-000760

Top guest favorite

An outdoor seating area features a circular table with comfortable chairs, positioned under a shaded patio. In the background, a sparkling pool is visible, surrounded by lounge chairs and red umbrellas, with lush greenery providing a serene backdrop.

Guesthouse in Paradise Valley Village

4.99 out of 5 average rating, 200 reviews

Casita Serena - beautiful, private and serene

Located in north Phoenix, this beautifully appointed 2 bedroom/1 bath guesthouse is 12 minutes from downtown Phoenix and the airport, in a vibrant community that boast a wide variety of locally owned businesses, restaurants and shops. It is a five minute walk to the Phoenix Mountain Preserve with beautiful hiking trails. Or just relax in the resort-like yard with pool, hot tub, and sitting areas. Please be aware the pool is not heated. STR Certificate #2020-175. Permit # STR-2024-002932

Top guest favorite

A comfortable studio space featuring a king bed with crisp white linens and decorative pillows. The kitchenette is equipped with modern appliances and wooden shelves. A ceiling fan offers a gentle breeze, and a cozy area rug adds warmth to the room.

Guest suite in Paradise Valley Village

4.97 out of 5 average rating, 317 reviews

North 32 studio, parking & outdoor living

Very quiet, safe residential area. Private parking, entrance, and great outliving space. Bbq & Fire pit/dining area/patio living area. Walking distance to several great restaurants/bars & coffee bars. Complimentary Access to nearby local Jabz Boxing - group classes of HITT style Boxing/Fitness. Enjoy this completely private, cozy getaway in the North Phoenix/Paradise Valley area that is close to many great restaurants, shopping, hiking trails, parks and close access to the Squaw Peak Freeway.

Top guest favorite

A living room features a dark sofa with red and white striped decorative pillows and a cozy red throw. A matching ottoman provides additional seating. Two lamps illuminate the room, and a framed coastal artwork adorns the wall, complementing the warm beige tones.

Guesthouse in Paradise Valley Village

4.93 out of 5 average rating, 136 reviews

Private Guest House w/King Bed, kitchen: Sleeps 4

Relax in this private "Beach House" in the desert. Located centrally to allow easy access to Westworld, Scottsdale TPC Golf course, Kierland Commons, Old Town Scottsdale, State Farm Arena, downtown Phoenix, and Spring training parks. Separate guest home includes large room with king bed, bathroom with washer, dryer, full kitchen including range, microwave, refrigerator. Kitchen table seats 5, living room includes queen sleeper sofa, television, cable. Includes all essentials for living.

Top guest favorite

A serene outdoor area features a private swimming pool reflecting palm trees and a clear blue sky. Comfortable lounge chairs surround the pool, alongside a shaded seating area under an umbrella, offering a perfect space for relaxation.

Villa in Paradise Valley Village

4.98 out of 5 average rating, 217 reviews

Villa de Paz

Looking for a sanctuary, a romantic getaway, a hiking haven? Come to Villa de Paz, a fully furnished, one bedroom casita, located on 2+ acres in the heart of Central Phoenix. Villa de Paz is located within walking distance of the Phoenix Mountain Preserve, known for its phenomenal hiking trails. Or, you can lay at the pool during the day and sit around the fire pit in the evening. Many restaurants are nearby or within minutes, you can drive to Scottsdale for shopping and entertainment.

Top guest favorite

The exterior of the Casita Bella AZ is shown, featuring a sleek, modern design. The building is set against a clear blue sky, framed by green desert vegetation, including a large cactus in the foreground. An outdoor shaded area is visible to the right.

Guesthouse in Paradise Valley

4.99 out of 5 average rating, 109 reviews

Paradise Valley Casita Near Old Town Scottsdale Az

Discover the perfect blend of serenity and excitement at Casita Bella AZ. This charming 1-bedroom, 1-bathroom detached guesthouse features a private entrance and electric gate for your convenience and safety. Immerse yourself in nature with a natural gas fire pit, calming water feature, outdoor jacuzzi, BBQ area and lots of open space. Nestled in the prestigious Paradise Valley, Casita Bella stands out with upscale amenities and tons of outdoor space to fully embrace the desert vibe.

Top guest favorite

A serene outdoor space features a lap pool surrounded by lush greenery. A shaded seating area with tables and chairs is visible, along with lounge chairs positioned for relaxation. Colorful potted plants add vibrancy to the patio, creating a peaceful setting.

Guesthouse in Paradise Valley

4.95 out of 5 average rating, 182 reviews

Jewel in Paradise

Beautiful newly remodeled separate and private guest house, 1-bedroom with a comfy bed plus a living room with a sofa bed. The mini kitchen, includes a Keurig coffee maker, microwave, stove, and mini-fridge. Bosch washer and dryer in the bathroom, with private entrance in Paradise Valley close to best things that Arizona offers. Spacious and relaxing, close to hiking, biking, golfing, shopping and entertainment. There is a large patio for your enjoyment, it's a great place to relax.

Top guest favorite

A spacious bedroom features a king-size bed with white bedding and red accent pillows. A dark wooden bed frame and nightstand complement the decor. Artwork adorns the walls, and natural light enters through window drapes, enhancing the comfortable atmosphere.

Guest suite in Paradise Valley Village

4.97 out of 5 average rating, 107 reviews

RESORT LIVING AT THIS BEAUTIFUL GUESTHOUSE

850sq ft. Newly remodeled attached guest house with vaulted ceilings. Large bedroom with king size bed and ample closet space, sliding mirrored closets. Living room, double vanity bathroom with large closet space, shower and separate toilet. Smart tv in living room and bedroom. Kitchenette with stove, large sink, fridge and new stackable washer and dryer. Private patio. Your private drive way in front of the guest house , off street with a separate entrance. Dog fee NO CATS

Top guest favorite

A patio offers stunning western views of the sunset, with desert scenery in the foreground. Saguaro cacti stand tall against the colorful evening sky, while a terracotta-tiled floor complements the rustic architecture of the surrounding walls.

Guesthouse in North Mountain

4.98 out of 5 average rating, 248 reviews

Saddle Lane Casita, North Central Phoenix, AZ

This hidden gem is centrally located on N Mountain in N Central Phoenix. 20 min to downtown Phx, 20 min to W. Valley, Scottsdale, Tempe, and Phoenix Int'l Airport. Our Casita features 1 room with a king bed, 1 bathroom, and a patio that faces west to enjoy Arizona's beautiful sunsets. We have a very steep driveway, and a full flight of stairs to the casita. If you have trouble walking or have knee and/or breathing problems, this is not the place for you.

Top guest favorite

A shipping container stands in a private outdoor area, featuring large glass doors that open to the interior. A paved red walkway leads to the entrance, bordered by decorative plants. The surrounding landscape includes gravel and a fenced area, with blue skies and clouds overhead.

Tiny home in Paradise Valley Village

4.92 out of 5 average rating, 297 reviews

The Zen Zone-Central PHX

Greet the morning sun by opening the sliding doors and enjoying tea or coffee in your own private backyard oasis. This space is designed for those seeking a unique experience! Includes WIFI and own private bathroom/shower (next door to container). Sleeps 2-3 comfortably. Centrally located to all PHX has to offer(15-20 minutes north of airport(just off I-51) and Downtown, 15 min. from Scottsdale. Great stop over on way to Sedona and Grand Canyon!