
Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 160 vacation rentals in Mesa

Nightly prices starting at
Mesa vacation rentals start at G$6,249 GYD per night before taxes and fees

Verified guest reviews
Over 14,330 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 40 rentals that welcome pets

Vacation rentals with a pool
50 properties feature pools

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
160 of Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Spacious Casita, Quiet, Peaceful Home - No Stairs!
Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

Unique urban habitat near ASU/downtown Tempe
Historic University Heights neighborhood is the location of this unique guesthouse adjacent to the host's home with it's own separate entry patio & parking. Short walk to Four Peaks brewery and Infusion Coffee. Sunny's Diner just 1/2 mile. Nearby grocers are Safeway, Trader Joe's, Whole Foods, Target.. Tempe Marketplace mall is a mile away. Free city shuttle and light rail train (goes thru Sky Harbor airport) are a four minute walk away. Close to 202,101 & 60 freeways. ASU is less than a mile.

Cozy Casita with kitchenette
Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

Historic Firehouse Downtown Chandler king bed
Welcome to the Historic Firehouse, strategically placed a mere 5-minute stroll from the vibrant Downtown Chandler hub, overflowing with culinary delights and upscale watering holes. This restored home has been magically reimagined into a charming Airbnb sanctuary. You will be greeted by a open living and kitchen leading to 2 bedrooms, complemented by 1 remarkable bathroom. With the capacity to house up to 7 guests, this abode is the setting for an escapade with your cherished companions.

Private studio! Central to popular locations.
Thanks for looking at the Copper State Casita. Our desert chic inspired casita is centrally located and nearby the Arcadia neighborhood. Tucked into an older neighborhood, it’s a 400 square foot studio with its own private patio. All the comforts of home in a small package. A short drive to Airport, Tempe, Scottsdale & Downtown Phoenix. Great for couples, business travel, friends, or small family. Just a few short minutes by car to trails, shopping & many popular restaurants.

Hacienda one bedroom with great pool
Heated pool, 8 seat hot tub, outdoor fireplace, and lots of patios to relax. The outdoor kitchen has a pizza oven, bbq, hot water sink, gas stove and oven, smoker and is a perfect place to enjoy. This place is close to restaurants, hiking, lakes and evening fun. Lots of trees: orange, grapefruit, key limes, lemons, pomegranate, figs, dates, grapes and there is a juicer for morning fresh juices. Safe, quiet, and has many hummingbirds and two giant (50 & 80 pound) tortoises.

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Detached Guesthouse | Full Kitchen & Parking
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Private Luxury Guesthouse in Mesa
Relax in this calm, stylish space. This guesthouse is the perfect getaway for couples or solo travelers. + King Bed + Sofa Bed + Firepit + Nespresso Machine + 2 Burner Cooktop + Cocktail Shaker Set + Full-Length Mirror + Comfy Robes + Rain Shower Head + Water Softener + Dedicated Parking + Private Entrance 8 min ➡ Downtown Mesa 10 min ➡ Downtown Gilbert 20 min ➡ Sky Harbor Airport 30 min ➡ Central Phoenix @glade.guesthouse

Sanitized Spacious Desert Getaway
Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Private-Detached Guesthouse & Zen Courtyard
Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals

Poolside Casita | Goats & Alpacas | Urban Farm

The Oasis Hideout

Mesa Casita with King Bed

Two Bedroom, Clean Guest House in Gilbert

Boutique Hotel Style Guest House

Entire Suite: Private and Cozy Clark House Casita

Scottsdale Luxury Guesthouse

The White Barn @ Freedom Farms
Guest house rentals with a patio

McDowell Suite

Private 2BR Midtown Casita + Yard

Cozy casita in a beautiful setting

Private yard - Short walk to Mill - Historic House

Charming & spacious Casita! Like home only better!

Entire Private Guest House with King Master

PHX's Modern Midtown Carriage House, Free Parking

Paradise Valley Luxe Casita + Private Oasis
Guest house rentals with a washer and dryer

Centrally Located Renovated Guest House

The Casita in Tempe Arizona

Enchanting Ahwatukee Secret Casita

Private and Quiet - 1 bdrm/1 bath Casita

South Mountain Hideaway

Spacious Studio in Uptown Historic Neighborhood

Guesthouse in city's most walkable neighborhood

Our Guest House at Papago Park
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- Phoenix Convention Center
- Lake Pleasant
- Chase Field
- TPC Scottsdale - Champions Course
- Grand Canyon University
- Grayhawk Golf Club
- State Farm Stadium
- The Westin Kierland Golf Club
- Peoria Sports Complex
- Salt River Fields at Talking Stick
- Desert Diamond Arena
- Surprise Stadium
- WestWorld of Scottsdale
- Sloan Park
- Arizona State University
- Tempe Beach Park
- Footprint Center
- Goodyear Ballpark
- Scottsdale Stadium
- Salt River Tubing
- Westgate Entertainment District
- Papago Park
- We-Ko-Pa Golf Club
- Camelback Ranch
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