Guesthouse vacation rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

Quick stats about guesthouse rentals in Mesa

  • Total vacation rentals

    Explore 160 vacation rentals in Mesa

  • Nightly prices starting at

    Mesa vacation rentals start at G$6,311 GYD per night before taxes and fees

  • Verified guest reviews

    Over 14,330 verified reviews to help you choose

  • Family-friendly vacation rentals

    30 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 40 rentals that welcome pets

  • Vacation rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    80 properties have a dedicated workspace

  • Wi-Fi availability

    160 of Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mesa rentals

  • 4.9 Average rating

    Mesa stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    Mesa's top spots, include Golfland Sunsplash, Sloan Park, and Hohokam Stadium

Top-rated guesthouse rentals in Mesa

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious California King bed is centered in the room, adorned with a white quilt. Two pillows rest against the headboard. Natural light filters through a window with blinds, illuminating the inviting sleeping area.
Guesthouse in Gilbert
4.94 out of 5 average rating, 503 reviews

Spacious Casita, Quiet, Peaceful Home - No Stairs!

Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

Top guest favorite
A spacious bedroom features a large bed with a colorful patterned blanket. Two nightstands with lamps are positioned on either side. Natural light filters through the fitted window treatments, highlighting the simple decor of the room. A small refrigerator is placed nearby.
Guesthouse in Chandler
4.95 out of 5 average rating, 337 reviews

Detached, Private, Clean & Safe Guesthouse with Large Patio

Everything you need in this super clean, cozy, and safe detached casita with private entrance & free parking. Conveniently located in an upscale neighborhood, close to DT Chandler’s shops, restaurants, and groceries. Nicely furnished with everything you need for a relaxing get-a-way: luxury linens, coffee maker, microwave, fridge, ice maker and hairdryer. Enjoy the large outdoor patio and BBQ. Dogs OK w/ a fee. Please note: there is no kitchen this unit. AZ License 26214654 Chandler STR 302084

Top guest favorite
Guesthouse in Mesa
4.97 out of 5 average rating, 208 reviews

Entire Suite: Private and Cozy Clark House Casita

Come and enjoy your stay at our unique and cozy casita in Clark historic neighborhood of downtown Mesa! Catch up on your favorite shows in the living room with our 65 inch HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom. Our space has a kitchenette to prepare meals, and a full size bathroom. You may also relax in the shaded patio surrounded by mature trees and lush greenery. No smoking or vaping inside or outside of the property.

Top guest favorite
A private room features a spacious bed with layered bedding, complemented by two decorative pillows. A small dining table with two chairs sits in the corner. Large windows with wooden shutters frame a view of greenery outside, and landscape artwork adorns the wall.
Guesthouse in Chandler
4.98 out of 5 average rating, 127 reviews

Cozy Casita with kitchenette

Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

Guest favorite
A cozy studio space is showcased with a king-size bed framed by bedside tables and lamps. A modern ceiling fan offers comfort overhead. A large flat-screen TV is mounted on the wall opposite the bed, with a console below for added storage. The flooring is finished in warm tones.
Guesthouse in Mesa
4.9 out of 5 average rating, 124 reviews

The Mesa Casita

The casita was just finished being completely renovated with brand new flooring, paint, appliances, kitchen cabinets, walk-in closet, bathroom, brand new BEDAGA king-size mattress, furnishings, whisper-quiet air conditioner, LED lighting, smooth stucco, and brand new fixtures (updated in January 2021). In addition, the casita has its own washer/dryer for your use only so you can travel light. CableTV, lightning fast WiFi, Amazon FireStick with Netflix are all provided at no extra charge.

Top guest favorite
Guesthouse in Chandler
4.92 out of 5 average rating, 199 reviews

Historic Firehouse Downtown Chandler Large shower

Welcome to the historic Firehouse, where you're a quick 5-minute stroll away from bustling Downtown Chandlers top-notch restaurants and bars. You're staying in a historic building that has been magically transformed into a cozy Airbnb retreat. Step Inside the Firehouse Garden with 2 stylish bedrooms that are ready to whisk you away into dreamland, 1 amazing bathroom. With enough space to accommodate up to 6 guests. This is the perfect spot for a getaway with your favorite people.

Top guest favorite
A bright and airy studio space features a comfortable bed with crisp white bedding and a cozy sitting area with a plush sofa. Natural light fills the room through the window, and a small bedside table with a lamp adds a touch of warmth.
Guesthouse in Mesa
4.98 out of 5 average rating, 314 reviews

Private, Convenient Studio Apartment

Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Top guest favorite
The entrance of the casita features a modern design with a stone column supporting the overhang. A walkway leads to a contemporary front door, framed by landscaped greenery and yellow flowers, creating an inviting entryway.
Guesthouse in Chandler
4.99 out of 5 average rating, 115 reviews

Chandler Estates

Come enjoy and relax in our cozy casita situated on an acre. It is 750sf with a full kitchen, family room, full bathroom with a walk-in shower, laundry, and its own exterior patio with dining, chairs and BBQ. Only minutes to downtown Chandler with a lively restaurant/bar and shopping area. If you love the outdoors enjoy the multiple golf courses, hiking, and biking trails all just a few a miles away. Airport is a short 20 minute drive with easy access to multiple freeways.

Top guest favorite
A bright and airy living space features a comfortable light-colored couch adorned with decorative pillows and a soft throw. A glass dining table for two is set beside a window with elegant window treatments, while wall art and decor add a touch of personality.
Guesthouse in Chandler
4.97 out of 5 average rating, 416 reviews

Private-Detached Guesthouse & Zen Courtyard

Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.

Top guest favorite
A well-lit bedroom features a king size bed adorned with a floral blue and white duvet. Natural light streams in through plantation shutters. A minimalist armchair and lamp complement the space, while a simple rug adds warmth underfoot.
Guesthouse in East Mesa
4.96 out of 5 average rating, 575 reviews

Mesa Casita with King Bed

Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

Guest favorite
Guesthouse in East Mesa
4.9 out of 5 average rating, 246 reviews

Orchard Cottage, Heated Pool and Hot Tub

Beautiful private self contained suite with a large heated pool and hot tub. Very private and far away from other living areas. Great fast internet, AC is new and works great (important in Arizona) and the bathroom shower is amazing. Lots of beautiful sitting spaces, sun or shade, relax at the pool or just hang out and read on the large hammocks.

Top guest favorite
A welcoming guest house is presented with a blend of white siding and natural stone accents, framed by lush greenery. A pathway leads to the entrance, flanked by well-maintained gardens. An American flag is displayed, contributing to the property’s inviting exterior.
Guesthouse in Mesa
4.95 out of 5 average rating, 182 reviews

The White Barn @ Freedom Farms

Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

Popular amenities for Mesa guesthouse rentals

Destinations to explore