House vacation rentals in Leon Valley

Lovely Home Medical Center, Spacious, Central

A spacious home built in 2005 and in a safe neighborhood in the Medical Center. With complete kitchen with things you needed to prepare a meal. Central to all the attractions and is 15-17 min to Military Airbase, Downtown . There's garden in the back yard with lots of seating/covered patio. We install back our KARAOKE with BOSE sound system. Free Parking in garage way and a dartboard are some of our amenities. Limited street parking but garage way good for 2. We strictly prohibit any party.

Cheerful 3 bedroom with hot tub

Enjoy all San Antonio has to offer at this pristine vacation rental. Featuring a private yard with a large covered patio, and a full kitchen, this lovely 3-bedroom, 2 bathroom home comes well-equipped for a fun-filled trip. Enjoy the San Antonio River Walk, SeaWorld, or relaxing in the hot tub. Family friendly with well equipped kitchen to prepare meals or play games at the oversized dining table. Conveniently located 5 min from Seaworld, 15 min to Lackland AFB, and 20 min from downtown.

Adorable Home by the Medical Center

Adorable, quiet and charming three bedroom home in the medical center area. Our home is accessible to main highway ( I-10, loop 1604 and 410). It is 20 minutes away from Sea World, Fiesta Texas, Lackland Air Force base and La Cantera and downtown. Major hospital like Methodist, VA , Christus Santa Rosa and University Hospital is only 5 minutes drive. Randolph Air Force Base and San Antonio Military Medical Center is 30 minutes away. The VIA bus system depot is less than a mile from the house.

The Sherlock Home a House of Conundrums!

The Sherlock Home is an immersive overnight experience. Please note- due to its unique escape-like intricate game there is an extra guest fee of $40 per guest over the initial two guests. Become Sherlock Holmes surrounded by a Victorian/steampunk setting filled with puzzles and conundrums to solve while you stay. The Sherlock home is like no other Airbnb. If you are looking for a one-of-a-kind adventure, come stay and play at The Sherlock Home. Deduce, decode, decipher -The game is afoot!

Cozy home near Medical center

Come stay under our 3-2, nice, clean and cozy home. We are located just 5 minutes near the Medical center, NW area of San Antonio, 15 minutes to the airport and North star mall, 20 minutes to Downtown, the River walk, Fiesta TX and shopping centers: La Cantera, The Rim, The Quarry Market. If you prefer to eat out, favorites like Chili's, Golden Corral Buffet, Hook & Reel Cajun Seafood & Bar are located nearby. For those who want to stock up on groceries an HEB is just 2 miles away.

Chic & Cozy House- Six Flags, Sea World, La Cantera

Relax in contemporary comfort with our stylish haven 5mins from Six-Flags & La Cantera, and 17mins to downtown! Our spacious home is designed with amenities that will put your mind at ease. Our guests can enjoy a luxurious soaking tub and elevated living/dining areas that are ideal for group feasts, leisure, and comfort. Enjoy a shaded backyard experience along with outdoor lights & grill, and at night gather around the firepit under the stars! Escape to Tranquility at the Casa Blanca!

Family Oasis, SeaWrld Fiesta TX | Bluebonnet Oasis

. Great location centrally located in great neighborhood. Private pool with several seating areas and a huge 2 level covered deck. Corn hole available to play while hanging out by the pool and gas barbecue available. 75” TV with all the apps loaded and sound bar with big bass. 50 inch upstairs and in billiards room.Lots of open space for making memories! Sleeps 10 comfortably with 6 beds and 3 bedrooms. Big open kitchen with everything you need to cook. PER CITY CODE NO PARTIES ALLOWED

Stylish, Charming Home In The Heart of San Antonio

Featured in Condé Nast Traveler. Enjoy a newly remodeled and tastefully designed home in a charming, elegant neighborhood in the heart of San Antonio. Our home is located in the Alamo Heights neighborhood, known as one of the best places to live in San Antonio & surrounding areas. Relax in our warm and welcoming home which is in close proximity to downtown, the airport, and major go-to spots and top restaurants in the city. We hope you have a wonderful stay in our beautiful home!

Haven away from home-King bed-Pool

Ideal home base for your family's visit to the Alamo City. Refreshing pool provides a fun space right outside your backdoor, or as you venture out into the city, find out what experiences, excitement, entertainment, and even a little intrigue await your family in this lovingly prepared home. Read more about our space to see what awaits! Perfect location with access to Six Flags, SeaWorld, Lackland AFB, Med Center, and the RiverWalk/Downtown SA, all in just a few minutes.

Medical Center/Star Wars Rm/Playground

Greetings from SA, Our modern charming home is centrally locally in the medical center area of beautiful San Antonio & within 15-20 mins from the SA Riverwalk, Sea World, Fiesta TX, Military Bases, & popular areas. It has 3 bedrooms & 2 full baths. Please review detailed pictures, description and other helpful information. NOTE: We also own the house directly across the street and can accommodate 8 guests at each home if traveling in larger groups.

Upgraded Townhome w Shared Pool in Gated Complex

Recently remodeled 3 bedroom townhouse in the NW side of San Antonio, just 10-15 minutes away from Lackland AFB, Sea World, Fiesta Texas, and the famous Alamo and Riverwalk. This 3 bedroom, 2 bath home located in a quiet gated community. The bedrooms include 1 king bed, 1 queen bed and 2 full beds to accommodate 6 adults comfortably. The community pool season is from May 30, 2026 to mid-September STR Permit #22-13500335 (Exp 03/02/2028)

4BR Retreat | Near Six Flags & La Cantera Shops

Welcome to Casa Serenidad — a peaceful retreat designed to help you slow down and unwind. Tucked away in a quiet San Antonio neighborhood, this single-story home offers a calming blend of comfort, simplicity, and design. Natural light, open living spaces, and serene surroundings create an inviting atmosphere where you can truly recharge, all while remaining conveniently close to San Antonio’s most popular attractions.