Places to stay near Des Moines Botanical Garden

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Top-rated vacation rentals near Des Moines Botanical Garden

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

The kitchen features classic wooden cabinetry and retro-style appliances, including a pale cream refrigerator. A patterned backsplash complements the checkered floor, while shelves display colorful dinnerware. Natural light fills the space, enhancing the inviting atmosphere for cooking and gathering.

Home in Ankeny

Historic Home on 4 Acres - Hot Tub, Pool, Tiki Bar

Our 1948 vacation home is on 4 acres & boasts 3 bedrooms, 3 full baths, 2 half baths, Bridal Suite (4th bedroom), 70s TV/Game Room, Tiki Bar, & Children's Playroom. Outside we have a pool (guaranteed to be open 5/26 - 9/5) & hot tub (year round). Located 15min away from Downtown DSM & a mile away from a grocery store/restaurants. Up to 2 dogs allowed for an additional fee. ***Events/photo shoots are allowed with written permission only and will be an added fee. No events larger than 25 total.***

4.97 out of 5 average rating, 210 reviews

Guest favorite

A dining area features a large wooden table with seating for twelve. Adjacent is a cozy living space equipped with comfortable sofas, two large smart TVs, and an arcade game. An outdoor area includes a fire pit and hot tub surrounded by wooden seating.

Home in Des Moines

The Hay Loft: Hot Tub • Game Room • Fire Pit • BBQ

Centrally located to Downtown Des Moines, sits our fully remodeled, 5 bedroom, 2 full bathroom home that can sleep 14 guests. The Hay Loft offers privacy for your large group, yet it's also close to everything that Des Moines has to offer! Our amenities include: spacious hot tub, fire-pit, grill, office space and a fully stocked kitchen. Fiber internet/WiFi + smart TVs in every room. Just a couple of blocks from Drake College, and within three miles of the Iowa Event Center and Casey's Center

4.99 out of 5 average rating, 151 reviews

Top guest favorite

A spacious living area features large windows, offering expansive views of the skyline. Modern furnishings include a cozy couch, two accent chairs, and a coffee table. A sleek electric fireplace is positioned beneath a wall-mounted TV, enhancing the contemporary design of the space.

Townhouse in Des Moines

This is the best Des Moines has to offer!

Welcome to a beautiful 3 story townhome in the heart of Des Moines. If an upscale modern home with an incredible view is your thing, you will be in heaven. Inside you’ll find a clean, bright and well decorated home with all the amenities you'll need to kick back, relax and enjoy your stay. Minutes from shopping, dining and nightlife. The bike trail is across the street where you can ride to Gray’s Lake or stroll to downtown DSM and enjoy the Farmer's Market, Civic Center and Principal Park.

4.94 out of 5 average rating, 151 reviews

Top guest favorite

A comfortable living area features a black leather sofa adorned with light-colored pillows, complemented by a dark brown ottoman. Soft light emanates from a floor lamp against a navy wall, while sheer curtains gently filter natural light. A massage chair is visible in the background.

Place to stay in Des Moines

Historic 1-bedroom carriage house apartment

Located in the heart of the Sherman Hill Historic District, this charming one bedroom carriage house has everything you need whether you’re visiting for business or pleasure. It features a plush king bed that guests rave about, a 50” television, massage chair, fully stocked kitchen, large shower, high end linens and beautiful courtyard. The property is within walking distance to downtown, historic Hoyt Sherman Place Theater, restaurants, a world class sculpture park and live entertainment.

4.98 out of 5 average rating, 393 reviews

Top guest favorite

A modern living area features a stylish sofa and a black and white patterned rug. A wall-mounted television is positioned above a sleek fireplace. A wooden dining table with high stools is set for two, and warm pendant lights hang overhead, illuminating the space.

Loft in Historic East Village

2 King Bed, East Village Loft, Perfectly Located

Our modern loft is in the heart of the Historic East Village district with an easy walk to everything and one parking space included. Walking distance to plenty of nightlife, the Farmer's Market, the Civic Center and Wells Fargo Arena. East Village is a vibrant neighborhood with shopping, great restaurants, entertainment and festivals! We are only a few blocks from the Des Moines trail system. Our place is perfect for couples, solo adventurers, business travelers, and families (with kids).

4.95 out of 5 average rating, 416 reviews

Guest favorite

Loft in Downtown Des Moines

Walnut Street Penthouse | Downtown Des Moines

A quiet, light-filled top-floor studio perched above downtown Des Moines. Set in a beautifully preserved historic building, this 12th-floor space offers soaring ceilings, skyline views, and a peaceful atmosphere that feels like your own private retreat in the city. Perfect for travelers craving a cozy, well-designed home base, the space blends modern comfort with timeless character. Steps away from all downtown has to offer — yet high enough above the noise to feel truly restful.

4.92 out of 5 average rating, 185 reviews

Top guest favorite

Apartment in Des Moines

Unique "Little Italy" Apartment

Drive into the attached garage and go upstairs where you will find your very private entrance to a quiet, peaceful, and restful living. Located 1 mile from the downtown area on a street loaded with large Oak and Walnut trees. A huge back yard in which to stroll or barbecue. It is the top half of my house complete with it's own kitchen, bathroom, and bedroom. My residence is the bottom half of the house. Lots of excellent restaurants nearby. Check out the "Guide to Restaurants".

4.95 out of 5 average rating, 995 reviews

Top guest favorite

A spacious living area features a modern design with a large sofa and two green accent chairs. A sleek entertainment unit with a fireplace is centered on the wall. Large windows provide natural light, enhancing the open and airy atmosphere.

Barn in Des Moines

8000sqft Barndo | Indoor Court + 2 Living Qtrs

Welcome to The Lodge on 3rd - a massive 8000 sq ft Barndominum. Nestled in the heart of Des Moines, Iowa, this stunning retreat offers the perfect blend of rustic charm and modern elegance. With 4 spacious bedrooms and a large loft, there is plenty of room for you and your guests to unwind in style. This property is next door to Luxury Living on Third. airbnb.com/h/luxurylivingonthird These combined properties are ideal for family reunions, etc. ***$200 Pet Fee***

5.0 out of 5 average rating, 174 reviews

Top guest favorite

A balcony view reveals a vibrant sunset casting shades of pink and orange across the sky. Silhouetted trees frame the scene, with distant buildings emerging in the background. A round glass table with colorful cushions offers a place to enjoy the view.

Home in Des Moines

Woodland Heights hist. district house on the hill.

Beautiful historic duplex house in the heart of woodland heights. Walking distance to downtown and next to Ingersoll avenue which is full of shops, bars, restaurants and more. Our place allows 2 parking spots on site with a side entrance to your upstairs Airbnb. The 800+ sq ft space includes a private kitchen, bathroom, bedroom, living room, and balcony with views of downtown. Picnic table and grassy area below balcony can be used on those nice Iowa days.

4.97 out of 5 average rating, 199 reviews

Guest favorite

The living room features large windows offering a skyline view of downtown Des Moines. Two stylish velvet chairs in pink and blue are positioned beside a small metallic table adorned with a floral arrangement. A shimmering 'Des Moines' sign enhances the ambiance.

Apartment in Historic East Village

Luxury | Skyline View | Downtown| Walk |Dream Room

Enjoy a luxury, unique experience at this centrally-located Flat in East Village across the river from Downtown Des Moines! Walking distance to Casey’s Arena, local shops, & restaurants. 7ft mirror and dedicated “Dream Room” for classy experience. Great for a girls’ weekend, a cozy couples’ stay, or a fun getaway with friends if you're after a little style and comfort in the city! Absolutely no parties. Brand new fitness center! Super-Fast Wi-Fi.

4.86 out of 5 average rating, 173 reviews

Top guest favorite

A comfortable living area features a large brown leather sectional sofa and a wooden coffee table displaying a magazine. On the blue wall, a colorful collection of framed artwork is visible. A subtle area rug complements the wooden flooring, while a stylish pendant light hangs above.

Apartment in Downtown Des Moines

Luxury Hotel Condo in Downtown Des Moines

Relax in this 1920s historical Liberty Mutual building condo. Bask in the abundant light from the large windows atop this ninth floor condo in the Hyatt Place Hotel. View the sunset over the State Capital and the iconic Travelers sign. Pick out some vinyl to play on the stereo. Enjoy our collection of original artwork or read a book from our eclectic biography library. For a video walkthrough go to: YouTube: search 418 Liberty Luxury Hotel Condo

5.0 out of 5 average rating, 236 reviews

Superhost

Home in Des Moines

Homey Drake Cottage Hideaway

Cozy, homey retreat near Drake University and minutes from downtown Des Moines! Relax in a comfortable living space with modern touches, cook in the fully equipped kitchen, and rest easy in bright, welcoming bedrooms. Enjoy fast WiFi, a smart TV, and all the comforts of home including a fully fenced backyard and private parking. Perfect for couples, solo travelers, or small groups looking for a warm, convenient stay in a friendly neighborhood.

4.85 out of 5 average rating, 113 reviews