Guesthouse vacation rentals in Downtown

Find and book unique guesthouse rentals on Airbnb

Quick stats about guesthouse rentals in Downtown

  • Total vacation rentals

    Explore 40 vacation rentals in Downtown

  • Nightly prices starting at

    Downtown vacation rentals start at G$10,450 GYD per night before taxes and fees

  • Verified guest reviews

    Over 5,220 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    40 of Downtown vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Downtown rentals

  • 4.8 Average rating

    Downtown stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Downtown's top spots, include Alamodome, Tower of the Americas, and San Antonio Museum of Art

Top-rated guesthouse rentals in Downtown

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in King William
4.9 out of 5 average rating, 297 reviews

Warm King Wm Getaway | Heated Pool Near Riverwalk

Perfectly located guest house in the highly-desirable King William Historic District puts you within walking distance of renowned eateries, clubs, shops, the Lone Star Brewery District, Downtown & the Riverwalk. <b>Our home offers</b> -Brand new pool and green space -Walkable to local favorite restaurants, shops, stores, and all of the downtown attractions -Short distance by foot or car to Riverwalk, Alamo & Pearl area -Short drive to Ft. Sam, Lackland, Parks, Zoo, family-friendly destinations.

Guest favorite
A cozy living area features a navy blue sofa adorned with patterned cushions and a round yellow pillow. A coffee table rests in front, displaying a magazine and a small white cup. Natural light filters through the nearby window, highlighting the room's inviting atmosphere.
Guesthouse in Tobin Hill Community
4.91 out of 5 average rating, 344 reviews

Ideal for Couples. Great value. Close to Downtown

250+ reviews. Cozy carriage apartment with urban San Antonio feel. Close to River Walk and the Pearl Brewery where you can find some of the city's favorite and eclectic dining spots, shopping and an incredible farmer's market. Nearby upscale shopping at The Quarry off US 281. Minutes from Zoo, River Walk and Airport. Great location for students/guests visiting nearby universities and families attending military graduations. Easy downtown access. Secure gated parking. Short Uber to downtown.

Guest favorite
Guesthouse in San Antonio
4.98 out of 5 average rating, 316 reviews

Private GuestHouse, King Bed-Patio with Dog Fence

A peaceful stay at our guesthouse. Close to Med Ctr & min frm dwntwn. It's a safe & comfy stay- full kitchen & private parking, king bed. Enjoy an evening by the fire pit before retiring for the night. We accept pets for a fee of $25 max two pets. An early check-in/late checkout may be available Pls inquire if you think you may need this option. Addl fee $ inv request sent for early check in/late checkout options. Pls inquire. Lmk if ur bringing ur pup - doggie station set up.

Guest favorite
Guesthouse in San Antonio
4.93 out of 5 average rating, 134 reviews

The Green Haus | 5 Min Downtown · Yard · Parking

Welcome to The Green Haus, a cozy 1-bedroom guest house just 5 minutes from Downtown San Antonio. Styled in calming shades of green and surrounded by mature trees, it offers a peaceful stay with a private fenced yard and free designated parking. The home is fully stocked with essentials, features comfortable furnishings, and includes board games for a relaxed night in—making it a comfortable, convenient, and budget-friendly retreat close to everything the city has to offer.

Top guest favorite
An open studio layout is presented, featuring a well-equipped kitchen and a dining table set for four. A cozy seating area is arranged with a brown sofa, while a unique wooden partition adds character to the space. Natural light illuminates from the windows, enhancing the inviting atmosphere.
Guesthouse in San Antonio
4.98 out of 5 average rating, 152 reviews

Cozy-Chic Studio/Terrell Hills

This unique cozy retreat is in a beautiful, conveniently located family and pet friendly community. You are just minutes away from so many of San Antonios finest and best places to visit such as: 1. Botanical Gardens, San Antonio Zoo, Japanese Tea Garden 2. The Historic Pearl 3. San Antonio River Walk 4. The Witte, McNay, Doseum and San Antonio Arts Museums 5. Fort Sam Houston Base and Golf Course, SA Country Club and Golf 6. Alamodome and SA Spurs Frost Bank Center

Top guest favorite
A serene outdoor space features a wooden deck lined with lounge chairs positioned beside a swimming pool. Lush greenery surrounds the area, complemented by a shaded seating area made of dark wood in the background, providing a welcoming space for relaxation.
Guesthouse in San Antonio
4.97 out of 5 average rating, 266 reviews

The Loft - Monte Vista

Our garage loft is a renovated and refurnished 900sf apartment. Clean, simple spaces and furnishings make for a relaxing getaway. We are in the Monte Vista Historic District, a 1-mile square walkable neighborhood 3 miles north of downtown and a 1.5 miles from the Pearl District. Our main house is a 1914 Prairie Style residence sheltered by the largest oak tree in San Antonio. We are happy to share our back yard, pool pavilion, and pool during our guests' stays.

Top guest favorite
Guesthouse in San Antonio
4.96 out of 5 average rating, 104 reviews

Fitzroy Guest House

Welcome to Fitzroy Guest House! Located minutes from all that San Antonio has to offer! Within 10 minute drive: - The Alamo - Riverwalk - Pearl Brewery - San Antonio Zoo - Japanese Tea Garden - Downtown San Antonio Within 20 minutes: - Seaworld - Six Flags Fiesta - Lackland Air Force Base - Fort Sam Houston Please note that the full bath is upstairs through the main bedroom. NO CLEANING FEES or CHECKOUT DUTIES! Our only request is for you to enjoy your stay!

Top guest favorite
A spacious bedroom features a king-sized bed with decorative pillows, flanked by two bedside lamps. Light wood flooring complements the soft wall colors, and large windows are dressed with light curtains. A patterned area rug adds warmth to the room's aesthetic.
Guesthouse in San Antonio
4.98 out of 5 average rating, 267 reviews

Newly furnished 1Bedroom apartment near The Pearl

Built in the 1920's but fully renovated apartment located above our detached garage. Think mother-in -law suite. Come enjoy a comfortable stay on our pillow top king sized bed. Cook a meal in our newly renovated kitchen. We added a touch of San Antonio through out the apartment so you can get a feel for San Antonio culture. Take a walk in the beautiful Monte Vista historical neighborhood that we are located in. We are centrally located in beautiful San Antonio!

Top guest favorite
A modern living area features a comfortable leather sofa and a decorative area rug. A large TV is mounted on one wall, opposite a well-equipped kitchen with sleek cabinetry. Natural light filters through sheer curtains, creating a bright and inviting space.
Guesthouse in San Antonio
4.99 out of 5 average rating, 103 reviews

Southtown Stablehand Suite

Discover this newly renovated 1-bed/1-bath gem in San Antonio’s vibrant Southtown! Steps from the Riverwalk, Alamo, Convention Center, and top eateries and bars! Walk to attractions and savor Southtown’s charm. Guests rave it’s “spotless” and “perfect” for couples or military families. “Will stay again!” Enjoy an included breakfast, Wi-Fi, and a luxurious mattress in a rustic-modern haven. Your serene escape awaits! Permit: STR-25-13500258

Guest favorite
The entrance showcases a sleek black door framed by decorative windows, providing a welcoming access point. A charming flower box filled with greenery and colorful blooms sits above, complemented by a stone pathway leading up to the entrance and stairs to the side.
Guesthouse in King William
4.94 out of 5 average rating, 144 reviews

Exquisite Studio Guesthouse Near Downtown's Core!

Indulge in unrivaled privacy and comfort within our recently remodeled 1-bedroom, 1-bathroom studio! Enjoy the charm of a snug getaway featuring a fully equipped microwave, refrigerator, and a generously sized bathroom. This prime location ensures easy reach to San Antonio's premier attractions, a mere 5-minute drive from the city center and less than 2 miles from both the Riverwalk and Pearl. Free street side parking is readily available.

Top guest favorite
Guesthouse in San Antonio
4.94 out of 5 average rating, 143 reviews

The Birdhouse in the heart of Terrell Heights

✨ 20% Monthly Discount Available! ✨ Charming guest house in Terrell Heights (Alamo Heights). Sleeps up to 4 with 2 queen beds. Centrally located: 🚗 15 mins to the Airport, Downtown, Zoo, The Pearl, and Fort Sam. 🚗 10 mins to the Botanical Garden, McNay Art Museum, and Witte Museum. 🚗 20-30 mins to UTSA, Fiesta Texas, SeaWorld, and Lackland AFB. Perfect for work, family, or fun — comfort and convenience in the heart of San Antonio.

Top guest favorite
A group of four is gathered outdoors, with trees and greenery in the background. They are smiling and posing closely together, reflecting a casual and relaxed atmosphere. The individuals appear to be enjoying a sunny day, dressed in comfortable attire.
Guesthouse in King William
4.94 out of 5 average rating, 392 reviews

Private Historic Charmer 3 Minute Walk From River

This humble, 80 year old, 500 Sq. Ft casita in King William Historic Neighborhood has a history of inspiring those who rest within its walls and over 5 years of hosting folks on AirBnB! Centrally located in King William Historic Neighborhood and close to the Riverwalk, Downtown, Convention Center, Alamo, BlueStar and Pearl plus easy access to Fort Sam, SAMC, Lackland, Randolph, & Medical Center. You will love staying here.

Popular amenities for Downtown guesthouse rentals