Vacation rentals in Downtown, San Luis Obispo

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Downtown, San Luis Obispo

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

A cozy living area features a comfortable gray sofa and a round coffee table adorned with decorative items. Large glass doors open to a private outdoor space filled with greenery, while soft natural light filters through sheer curtains.

Loft in Downtown SLO

4.99 out of 5 average rating, 531 reviews

Stylish and Comfortable Lofted Townhouse, Downtown SLO

Our goal is make you THRILLED to be here. Sparkling clean, luxurious and cozy. All amenities have been thoughtfully provided, similar to a 5-star hotel...luxury linens, feather-topped bed, plush robes, a lovely garden-like patio on which to enjoy your coffee or an afternoon wine and cheese plate. And first-day breakfast items are included for you to enjoy at your leisure!..organic Eggs, local baked goods, coffee, espresso, juice, fruit and yogurt. Most importantly, the location is a Dream! Just a few blocks from the downtown cultural-hub. The Perfect Location to come experience the “SLO Life”! The Loft was professionally designed to make you feel pampered and pleased! You won’t want to leave!! Perfect for Romantic get-aways, a fun Girls-Trip, and business travelers alike. We love to travel, and we appreciate the FINE details that set a place apart from the rest. We have put that experience to use here. All amenities have been thoughtfully provided. Similar to a 5-star hotel, you will find wifi, smart TV, a quaint electric-fireplace in the bedroom, luxury linens, comfy bed, plush robes, a lovely garden-like patio on which to enjoy a nice breakfast or enjoy an afternoon wine and cheese plate. And breakfast items are included for you to enjoy at your leisure..local Eggs, Local baked goods, Coffee, Illy Espresso, Orange juice and Fresh fruit await your arrival. You will be in the epicenter of all SLO has to offer, but JUST far enough away from the bustling downtown area to not be bothered by the noise or the late night crowd. Hiking trails abound here and the iconic Pismo and Avila beaches are mere minutes away. Come pamper yourself at the Loft. Our reviews say it all!... ~Recent Guest Comments: "Fantastic location. Walking distance to all that is going on in downtown SLO. The decor was so nice and the loft was planned carefully to provide everything you could possibly need during your stay." -Pam "Thanks for everything! This was my favorite Airbnb stay to date and I want to thank you for your responsiveness and for allowing us to stay. Would love to stay again soon!" - Andrew "The cleanest Airbnb we've stayed in to date. We will be back." - John Guests will have exclusive access to the entire home. Your Reserved parking space is just steps from your front door. Laundry facilities are on site. You have a private garden-like patio on which to sip your morning coffee or enjoy an afternoon wine and cheese plate. We are available to answer any questions and offer suggestions from where to eat to what to do during your visit here in SLO county! If you need anything more, please ask. We aim to please! The loft is within walking distance of the coffee houses, eateries, and shops of the Old Town Historic District, Thursday Night Farmer's Market and the Historic Mission. There are many great parks in the area that offer wonderful walking/biking/hiking trails, and Cal Poly State University is a short drive away. A few minutes to the South of the Loft you will find yourself in the beautigul heart of Edna Valley wine country. Iconic Avila, Shell and Pismo Beaches are a mere 10 minutes away as well. Train | Plane | Car | Bus SLO Amtrak train station is just .4 miles from our condo. SLO County Regional Airport - 2.8 miles. Regional Bus service has easy access The heart of Downtown SLO is a 3 minute walk For transportation to or from the airport may we recommend Ride Uber at San Luis Obispo County Regional (SLO) Airport The space is cozy and perfectly suited for two.

Top guest favorite

A charming garden area is framed by brick pathways, with a wooden table and chairs positioned nearby. Lush greenery and various plants create a serene outdoor atmosphere, while a wooden gate provides privacy and access to the space. The ground appears damp, suggesting recent rain.

Guesthouse in San Luis Obispo

4.98 out of 5 average rating, 587 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Top guest favorite

A vintage-inspired kitchen features white cabinetry and open shelving displaying a variety of decorative dishware. A well-appointed stove and sink are included, along with subtle decor elements such as potted plants and a floral arrangement, creating a warm and welcoming environment.

Apartment in Downtown SLO

4.99 out of 5 average rating, 290 reviews

Eclectic apartment in the heart of downtown SLO.

This charming, newly updated, 1 BR apartment is part of an 1883 Folk Victorian in the heart of SLO's downtown historic district and was recently added to the California Master List of Historic Resources as 'The D.M. & Carrie Proper Meredith House'. This cozy apartment offers convenience, style, safety, and privacy - all while being just a two-minute walk to all your favorite bars, restaurants, cafes, movie theatres, and shops. Your hosts aim to provide you with an amazing 5-star experience!

Guest favorite

A light-filled studio is presented with a spacious bed, blue cabinetry, and a full kitchen that includes a microwave and stove. A small dining table with black chairs is positioned near the windows, providing a view of the room's warm wooden flooring.

Guesthouse in Downtown SLO

4.97 out of 5 average rating, 558 reviews

Downtown Historic District Sunset Studio

Enjoy a hotel quality stay, professionally cleaned prior to each guest, located in the beautiful downtown historic district. Studio is equipped to provide you with everything you need for an enjoyable stay; including washer/dryer, AC/ Heat. From the deck enjoy magnificent sunset views framed by San Luis Mountain and Bishop's Peak while enjoying dining al fresco. We are 4 walkable blocks to downtown and a mile to Cal Poly. The beach is about a 10 min drive away. You can't beat the location!

Top guest favorite

A backyard patio features a circular fire pit surrounded by comfortable seating. String lights hang overhead, providing a warm glow. Greenery lines the perimeter, and the space is paved with stone tiles, creating an inviting area for relaxation and socializing.

Home in Downtown SLO

5 out of 5 average rating, 158 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Sit back next to the fire pit in the backyard, it's just a 7 min. walk to downtown & next to 5 restaurants including Sally Lou's coffee shop, Terrace Hill trail head & the train station. Experience SLO's charm like never before with this perfect location home. Book a stay!

Superhost

The kitchen area features white cabinetry and stainless steel appliances, including a refrigerator and stove. A wooden countertop provides workspace beside a high-top table with seating. The floor is covered in light-colored planks, and a red door is visible in the background leading outdoors.

Home in Downtown SLO

4.83 out of 5 average rating, 145 reviews

Cozy Studio Close to Downtown SLO

Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Top guest favorite

A historic two-story home is depicted, showcasing detailed architectural features such as a wide front porch with white railings and decorative columns. The exterior is painted in soft green hues, surrounded by landscaped gardens and trees, with a sign indicating its location in the Mill Street Historic District.

Place to stay in Downtown SLO

4.97 out of 5 average rating, 498 reviews

Rooftop Patio Downtown Suite- 4-5 Guests

Historic 1887 home with modern interior. Entire upper floor suite (700 sq ft) with private entrance, galley kitchen, laundry, common space (recently updated w/ comfy seating for 4-see photos below!), bathroom and two bedrooms. This space was remodeled in 2019 and has a fully equipped kitchen and private rooftop deck with views of Cerro San Luis and Bishop Peak. Stroll out your door and find downtown SLO a couple blocks away. Cal Poly is located 1 mi away. Homestay Lic # 115822

Top guest favorite

A welcoming entrance is framed by lush green foliage and vibrant purple flowers. A rustic wooden sign reading 'Welcome' adorns the fence, complemented by a small mat leading to the entrance. Soft sunlight filters through the leaves, creating a serene atmosphere.

Guesthouse in Downtown SLO

4.98 out of 5 average rating, 626 reviews

Cottage in SLO / Historic Downtown District

“Cottage in SLO” is located in the historic district of San Luis Obispo with its century old homes and buildings. Enjoy the three block walk to downtown with all its amenities: Restaurants to please every pallet, from BBQ to gourmet. Coffee shops, theaters, galleries, and the world famous Farmers Market event every Thursday night. Bike paths are on the same street that will take you anywhere in SLO and beyond. . (Bikes provided) Perfect for two. Homestay permit # -0606-2019

Superhost

The living area showcases a blend of mid-century and contemporary furnishings. A couch faces a low coffee table, while a television is positioned on a wooden cabinet. Natural light fills the space through two windows, creating a warm and inviting atmosphere.

Apartment in Downtown SLO

4.84 out of 5 average rating, 341 reviews

Midtown SLO apartment

Cozy up to the fireplace for a relaxing evening in the heart of everything San Luis. This charming 600 sq ft upstairs apartment, fully and stylishly furnished in a small quiet tri-plex, perfectly located just 2 short blocks to beautiful, lively downtown San Luis Obispo. It’s an easy walk to restaurants, unique shops, the Mission, wine tasting, art viewing and the famous farmers market on Thursday night and less than one mile to Cal Poly. Homestay Permit # HOME-0005-2020

Superhost

A spacious living area features a plush black couch adorned with decorative pillows. A coffee table with a potted plant sits in front, while a dining area with wooden chairs and a light fixture is visible in the background. Light streams in through multiple windows.

Home in Downtown SLO

4.78 out of 5 average rating, 149 reviews

Cozy Retreat Walking Distance to Downtown

This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

Top guest favorite

A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.

Home in Downtown SLO

4.96 out of 5 average rating, 402 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Top guest favorite

A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.

Home in Downtown SLO

4.98 out of 5 average rating, 234 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.