
Places to stay near Cleveland Botanical Garden
Book unique vacation rentals, homes, and more on Airbnb
Top-rated vacation rentals near Cleveland Botanical Garden
Guests agree: these stays are highly rated for location, cleanliness, and more.

Little Italy 3, close to Cleveland Clinic, CWRU
Enjoy a uniquely styled experience at this boho-chic apartment in the heart of Little Italy. Exposed brick walls, hardwood floors, and wooden furnishings combine to give this apartment a boho-chic aesthetic. Enjoy dinner in the cozy kitchen and watch TV while relaxing on the comfortable sofa. One flight of stairs is leading up to the second floor (17 steps)The unit is on a quiet side street in walking distance to the heart of Little Italy (restaurants,cafes, shops).Free parking on premises(1car)

In the heart of Little Italy! Free Parking! 3BR-UP
Enjoy your stay at this centrally located - upper unit- in a two-family home in Little Italy. Apartment is complete with a well-equipped kitchen. The living room includes comfortable seating for 6, a smart TV, 3 poufs & coffee table - so that ALL may rest their feet from a long day, modern furnishings and a washer/dryer/linen closet. Each bedroom includes USB plugs in the lamps, alarm clocks with sound machines, blackout curtains, ceiling fans, Smart TVs, "ultra-quiet" ACs, desk, chair & mirror.

Historic Little Italy Garden Apartment
Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.

New! “Modernistic Retreat”
Elevate your stay in this bright, elegant and spacious 3rd floor apartment that offers the perfect blend of tranquility and urban convenience. Less than 10 minutes from Cleveland Clinic, 8 min from Case Western University, 17 min from Rock and Roll Hall of Fame, 18 min from Cleveland Browns Stadium, 20 min from Downtown, 28 min from Cleveland Airport and 45 min from Blossom Music Venue. Moments from charmed local neighborhoods such as Coventry, Little Italy, Cedar Fairmont and Lee Rd.

Rare Cleveland Apt: Little Italy! W/Sauna&Hot tub!
Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated in the heart of Little Italy, walking distance from University Circle, UH Hospital, Cleveland Museum of Art, Botanical Garden, Public Transportation and much more. Apartment is complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation/business rental delivers all the essentials so you can spend more time relaxing and exploring.

Private Victorian suite with two rooms and a bath
You’ll love this newly remodeled third floor suite in our large century home located near Coventry Village/University Circle/Cleveland Clinic. The private suite with separate entrance and stairs has an air conditioned large bedroom with a firm queen bed, a sunny sitting room with a futon and a bathroom (shower) finished in Victorian ornate wood trim! Off street parking is in the rear. Our place is great for couples or business travelers, and the futon can sleep a child on.

Star Wars–Themed Home w/ Arcade | Family-Friendly
Enjoy your stay at a newly updated Star Wars–themed family home- perfect for relaxing getaways, extended stays, or families needing comfortable temporary housing nearby. 📍 Nearby: • Cleveland Clinic – 20 min (medical stays & visits) • Pinecrest – 6 min (dining & shopping) • Cuyahoga Valley National Park – ~20 min (trails & scenic railway) • Downtown Cleveland – ~20 min (museums & sports) • Hopkins Airport – 20 min (easy travel access) 🚭 Smoke-free & pet-free home

Clean and Cozy Carriage House Getaway
Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.

Peaceful Mansion Studio | Steps from Cle Clinic
🛏 Queen bed • 1 bathroom • Sleeps 2 🏛 Historic Cleveland mansion • Second floor studio 🍳 Full kitchen • Smart TV • Streaming apps 🚗 Free off-street parking • Quiet location 💤 Peaceful, comfortable & full of charm 📍 Directly across from Cleveland Clinic Main Campus (10 min walk, 2 min drive) Step back in time while enjoying modern comfort in this bright and colorful studio nestled inside a beautifully restored Cleveland mansion.

Cleveland's Little Italy #2 *Family Run*
Located in Cleveland’s historic Little Italy, my two-bedroom, one-bath units are steps from Mayfield Road’s restaurants, bakeries, and galleries, with easy access to University Circle, Case Western, and the Cleveland Clinic. Hosting since 2011, I personally manage everything to provide a level of care big companies can’t match. I’m always improving my spaces to ensure a comfortable stay—if something’s missing, just let me know!

Historic Little Italy Two Bedroom w/ Private Drive
*** This apartment is in a very quiet building. Be understanding and respectful of the noise level at all times. *** Unwind in this historic & stylish two bedroom apartment in Little Italy, an area with historic and cultural charm. Little Italy is full of award-winning restaurants, bars, shops, art galleries, and attractions. Adventure through Little Italy, University Circle, and Downtown Cleveland from this prime location.

Log Cabin Retreat
A Rustic Retreat with a Refined Interior! This 1960's Log Cabin nestled in the woods above the Rocky River is a beautiful place to unplug and unwind. Located within a mile of the Cleveland Metroparks System including miles of hiking, biking and horse trails, golf courses, fishing spots and picnic areas. It is 20 minutes to downtown Cleveland and 5 minutes to Cleveland Hopkins Airport. NO PETS or PARTIES, please.
Popular amenities for vacation rentals near Cleveland Botanical Garden
Other top sights near Cleveland Botanical Garden
Condo rentals with wifi

Downtown CLE Loft | King Bed | Walk to Everything

New Penthouse Roof Deck Walk 2 Cavs/Browns/Indians

Chic home near Cleveland airport

Luxury Top Floor Condo with a View

Retro Nostalgic Condo in the heart of Lakewood

Cozy Condo

A Cleveland Modern & Historic Apartment 106-1

Tito’s Toast of Cleveland - A Rock & Roll Retreat
Family-friendly house rentals

Luxury Downtown Townhome w/ Private Garage Unit 6

Steps to Cleveland Clinic - Bright Studio

Blue Historic House by Cle Clinic, CWRU, Museums

Cozy Heights Oasis-Walk to Restaurants

Private Tremont Century Home

Sunlit Urban Oasis | freshly furnished 1890 home

Cle Heights Nature’s Getaway | 2bed1bath | AC Pets

Tremont • urban cottage
Apartment rentals with air conditioning

Rock 'n' Roll Retreat ~15min to DT~8min Cle Clinic

Comfy 1B1B w/ Wi-Fi, Gym + Parking

2BR in Little Italy, 5 min walk to Case & UH

Private Modern Retreat Mins From Clev Clinic & UH

Cle Suites 1BR/1BA | 5 min Walk to Cle Clinic #10

Modern Tremont Loft — Steps to Dining & Parks

Sleeps 3 | Downtown & Museums Nearby

Flats + City View + Modern + Balcony + Parking
Other great vacation rentals near Cleveland Botanical Garden

Cheerful, Scandinavian, Midcentury 2 bedroom home

"Historic Charm - Loft in the Heart of Cleveland"

Strawbale Private suite near CCF, CWRU, UH.

New Luxury Studios | Walk to Cleveland Clinic

The Nook near Clev clinic, CWRU

The Carriage House

*RARE FIND>next to UH, CC, CWRU!

Downtown Suite w/ Amazing Views
Destinations to explore
- Cuyahoga Valley National Park
- Rocket Mortgage FieldHouse
- Progressive Field
- Pro Football Hall of Fame
- Rock & Roll Hall of Fame
- Cleveland Browns Stadium
- Headlands Beach State Park
- Gervasi Vineyard
- Mosquito Lake State Park
- Cleveland Metroparks Zoo
- Case Western Reserve University
- Punderson State Park
- Boston Mills
- Agora Theatre & Ballroom
- The Arcade Cleveland
- Laurentia Vineyard & Winery
- Cleveland Museum of Art
- Huntington Convention Center of Cleveland
- Cleveland Museum of Natural History
- Playhouse Square
- Crocker Park
- Debonné Vineyards
- Rocky River Reservation
- Edgewater Park Beach





