Vacation rentals in Clayton County

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Top-rated vacation rentals in Clayton County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite

A single-story cabin is featured, showcasing a green metal roof and natural wood siding. Large windows allow for ample natural light, while a welcoming front door, framed by a stone chimney, leads to the quiet surroundings of the property.

Cabin in Woodman

5 out of 5 average rating, 63 reviews

River Trails Cottage

Have fun with the entire family or a group of friends in a quiet peaceful setting. The cabin sits on 2 acres and attaches to 8700 acres of public land that is open to hunting, hiking and abundant with wildlife which makes this property great for the outdoor enthusiast. The property is 6/10 mile from a public boat landing where you can fish, kayak or canoe the Wisconsin River. There are multiple parks relatively close that offer excellent hiking trails. Direct access to miles of ATV/UTV trails.

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Guest favorite

A quaint blue house is shown from the side, surrounded by lush green grass. A wooden fence partially outlines the property, with a few flowering plants positioned along the edge. Clear skies and sunlight illuminate the exterior, highlighting its welcoming presence.

Home in Prairie du Chien

4.98 out of 5 average rating, 172 reviews

Ohio Street Retreat- hot tub, massage chair, pool

After a fun day in The Driftless Area, come relax and unwind in Prairie du Chien. Beautifully decorated 2 bedroom home with a spacious kitchen, large island, dishwasher, washer/dryer & 5' walk in shower. We supply all cooking/baking items/utensils. High-speed internet with smart TVs in both bedrooms and living room. Outdoor pool (seasonal), hot tub and massage chair. We love dogs too, so we provide a dog run (there is a pet fee). For our fishermen- there is off street parking for your boats.

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Guest favorite

The image shows a wooden staircase leading down from a covered porch, framed by railings. A pathway is visible at the bottom, covered with grass, and a grassy area extends beyond. A small shelter with a blue roof stands in the distance.

Home in Elkader

4.86 out of 5 average rating, 35 reviews

Small-town Charmer (please read- rural location)

Relax with the whole family at this peaceful place to stay. 3 bedrooms 2 bathrooms. Quiet area close to nature and scenic roads and parks. Nestled between Elkader and Strawberry Point. Close to Backbone State Park and Volga/Turkey Rivers. This is a rural property, not located in a town with any amenities. You must bring what you need or plan to travel 8 miles to Elkader (Dollar General, Wilkes Grocery, pit stop gas station)or strawberry point (Dollar General, Casey’s and Nadings gas stations)

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Top guest favorite

A clear drink adorned with lemon slices and colorful ice cubes rests on a wooden deck railing. In the background, the tranquil waters of the Mississippi River reflect the sky, framed by lush trees and a peaceful shoreline.

Home in Cassville

4.85 out of 5 average rating, 127 reviews

Right on the Mississippi...relax and enjoy!

Our little spot is right on the mighty Mississippi river, a beautiful spot to relax, fish, bird watch including eagles! We feature a large deck facing the water to enjoy morning coffee or an evening cocktail to watch sunsets. When you’re ready to settle in for the evening, we have ready-to-cook kitchen, grill, WiFi, Amazon Prime and Netflix, fireplace and comfy seating. So just relax! Small Wisconsin town with BIG relaxation. See more in this video! https://youtu.be/rM2HnmNMu4U

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Top guest favorite

A lush green landscape rises just beyond a calm river, with a small collection of buildings visible along the shore. The architecture varies, featuring both traditional and modern designs, under a sky filled with fluffy clouds.

Apartment in Clayton

4.94 out of 5 average rating, 176 reviews

Cozy Apartment Steps from the Mighty Mississippi

Disconnect from the daily grind and enjoy a getaway in this welcoming one bedroom apartment, steps away from the Mighty Mississippi. Located in Clayton, Iowa, Located within walking distance of two delicious restaurants and a boat launch., and only 1/2 hour from the Casino Queen, local wineries, Pikes Peak State Park, as well as the historic communities of Elkader, IA and Prairie Du Chien, WI. Need more space? I also offer a two bedroom apartment: www. airbnb. com/rooms/43979345

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Top guest favorite

Apartment in McGregor

5 out of 5 average rating, 29 reviews

Historic Charm in the Heart of McGregor, Iowa

2 Bedrooms • 1 Bathroom • Walk to the Mississippi River Welcome to your cozy getaway in the scenic river town of McGregor, Iowa! This beautifully updated two-bedroom, one-bath home combines small-town charm with modern comfort — perfect for couples, families, or friends looking to relax and explore. A bright, open living area with comfortable seating and local decor A fully equipped kitchen with everything you need to cook and dine in. Two spacious bedrooms with plush bedding.

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Guest favorite

Home in Marquette

5 out of 5 average rating, 20 reviews

Pleasant Ridge Retreat

Charming 2-Bedroom Retreat Near the Mississippi River Just half a mile from the Mississippi River, this newly built 2-bedroom, 1-bathroom home offers the perfect escape for nature lovers, history buffs, or anyone looking to unwind in a tranquil setting. With an open-concept design, modern finishes, and plenty of natural light, this cozy retreat is ideal for summer getaways or fall stays to enjoy the vibrant autumn scenery.

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Top guest favorite

The exterior of the 1884 Red Brick Cottage is shown, featuring a classic brick facade and a welcoming front porch with a screened area. Lush green lawns surround the property, with a driveway leading to the house. Scenic hills are visible in the background.

Home in Marquette

4.96 out of 5 average rating, 206 reviews

1884 Red Brick Cottage

Step back in time to a quiet small town in Iowa, nestled within the hills of the driftless area. Time seems to stand still while you're here. The 1884 Red Brick Cottage offers 3+ Bedrooms in a peaceful neighborhood, close to riverfront activities, casino and downtown Marquette. Spacious backyard and sideyard, house is fully furnished and includes a firepit and gas grill for evening outdoor activities.

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Superhost

A brick cottage is set among lush green grass, with a metal roof and partially covered by climbing vines. Decorative plants line the base of the house, and trees surround the property, adding to the natural landscape.

Cottage in Garnavillo

4.69 out of 5 average rating, 154 reviews

Valley Mills Miller's Cottage

Welcome to Valley Mills Miller's Cottage, where the beauty of "Mother Nature" surrounds you. Built six years after Iowa became a state in 1847, it is located in a remote picturesque valley containing Buck Creek Trout Stream. It is completely surrounded by wooded Bluffs, known as "Cold Slopes". With its two acre park like area, it is an ideal place for families to let their Kids/pets freedom to roam.

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Guest favorite

A rustic home's exterior is presented, showcasing a white façade with multiple large windows and a welcoming front porch. The porch features wooden steps, inviting entry. Surrounding greenery and a blue sky with clouds enhance the home’s charm, though no additional structures are visible.

Home in Prairie du Chien

4.9 out of 5 average rating, 40 reviews

Rustic 3Bed 2Bath Home near Downtown PDC

Bring family and friends to this rustic home located in Historic downtown Prairie Du Chien and 1 block from the river. Great location that puts you near all of the events this town has to offer. You are also 5 min from the casino!Whether you are visiting for the Mississippi River, downtown scene, hunting, fishing, or just to getaway for relaxation, this place will accommodate your interests!

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Guest favorite

Home in Guttenberg

5 out of 5 average rating, 20 reviews

Secluded Bardo Retreat w/ Hot Tub + View

Find Your Stillness | Omega Ridge Retreat on 6 Private Acres This one-of-a-kind property features a brand new Barndominium, perfect for couples’ getaways, family gatherings, small retreats, or anyone longing to unwind in nature without sacrificing comfort. This area is great for hiking hunting fishing, canoeing side-by-side riding & near the historic town of Guttenberg just 6 miles away.

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Top guest favorite

The kitchen features modern appliances and a spacious island with seating for several guests. Light wood cabinetry complements the kitchen's decor. A dining area with a wooden table and chairs is visible in the background, illuminated by natural light from nearby windows.

Home in Monona

4.98 out of 5 average rating, 136 reviews

Driftless Manor Getaway

The Driftless Manor Getaway is a perfect location for you and your friends or family to stay! The Driftless area has many activites such as antiquing, biking, boating, fishing, gambling, hiking, hunting, shopping, and winery/brewery hopping! Come explore the area to see what adventures you can find while staying in a roomy, relaxing space!

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