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Hotels in Clarendon County

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Top-rated hotels in Clarendon County

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Hotel room in Manning
4.2 out of 5 average rating, 15 reviews

Best Inn with King Bed, WiFi, Private Bathroom

Whether you’re here for a quick stop or a longer stay, our cozy, reliable inn offers comfort, great value, and easy access off I-95—an ideal halfway point between the Northeast and Florida for road trippers, business travelers, and vacationers. • Guest rooms with comfortable bedding, free Wi-Fi, cable TV, mini-fridges, and microwaves • Pet-friendly • Daily housekeeping to keep things fresh • Free parking right at your door • 24/7 front desk support—we’re always here for you

Hotel room in Manning
4 out of 5 average rating, 13 reviews

Best Inn with 2 full size bed, WiFi, bathroom

Whether you’re here for a quick stop or a longer stay, our cozy, reliable inn offers comfort, great value, and easy access off I-95 an ideal halfway point between the Northeast and Florida for road trippers, business travelers, and vacationers. • Guest rooms with comfortable bedding, free Wi-Fi, cable TV, mini-fridges, and microwaves • Daily housekeeping to keep things fresh • Free parking right at your door • 24/7 front desk support—we’re always here for you

Hotel room in Santee

Club Wyndham Lake Marion - Three Bedroom Deluxe

Lakeside charm allows your family to experience a true escape to this peaceful retreat on the calm, tree-lined banks of Chapel Branch, an inlet of South Carolina's largest freshwater waterway, Lake Marion. Visit the State Park for miles of hiking and biking trails, indulge in a variety of popular water sports, take a romantic evening boat ride or catch fresh fish for dinner right off the dock. Experience a true escape from the everyday life at this peaceful retreat.

A multi-story building features a stone and brick facade, with numerous balconies overlooking the tranquil waterway. Surrounding trees display autumn foliage, while a dock is visible in the foreground, enhancing the serene lakeside environment.
Hotel room in Santee
4.92 out of 5 average rating, 12 reviews

Club Wyndham Lake Marion - Two Bedroom Deluxe

Lakeside charm allows your family to experience a true escape to this peaceful retreat on the calm, tree-lined banks of Chapel Branch, an inlet of South Carolina's largest freshwater waterway, Lake Marion. Visit the State Park for miles of hiking and biking trails, indulge in a variety of popular water sports, take a romantic evening boat ride or catch fresh fish for dinner right off the dock. Experience a true escape from the everyday life at this peaceful retreat.

Hotel room in Santee
New place to stay

3BD/3BA at Lake Marion

Set along the shimmering shores of Lake Marion, this relaxed retreat is all about waterfront living. Spacious villas offer room to unwind, while a private boat dock and easy lake access invite days of fishing, cruising, and sunset views. Enjoy outdoor pools, walking paths, and peaceful nature all around. Just a short drive from local dining and small-town charm, it's the perfect escape for laid-back lake days and breezy evenings by the water.

Hotel room in Santee
New place to stay

2BD/2BA at Lake Marion

Set along the shimmering shores of Lake Marion, this relaxed retreat is all about waterfront living. Spacious villas offer room to unwind, while a private boat dock and easy lake access invite days of fishing, cruising, and sunset views. Enjoy outdoor pools, walking paths, and peaceful nature all around. Just a short drive from local dining and small-town charm, it's the perfect escape for laid-back lake days and breezy evenings by the water.

Hotel room in Santee
New place to stay

Deluxe 3-Bedroom Retreat on Lake Marion

Escape the ordinary at this peaceful three‑bedroom lake retreat on Lake Marion’s Chapel Branch. Ideal for families or groups, your spacious unit provides easy access to 311 miles of shoreline and excellent fishing (30+ species). Explore Santee State Park for hiking and mountain biking, tee off at one of three nearby golf courses, or relax lakeside and enjoy the views. Comfortable, well‑appointed accommodations perfect for outdoor adventures.

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Hotel room in Santee
New place to stay

Spacious 3-Bedroom on Lake Marion

Escape the ordinary at this peaceful three‑bedroom lake retreat on Lake Marion’s Chapel Branch. Ideal for families or groups, your spacious unit provides easy access to 311 miles of shoreline and excellent fishing (30+ species). Explore Santee State Park for hiking and mountain biking, tee off at one of three nearby golf courses, or relax lakeside and enjoy the views. Comfortable, well‑appointed accommodations perfect for outdoor adventures.

Hotel room in Santee
New place to stay

Scenic 2-Bedroom Deluxe on Lake Marion

Escape the ordinary at this peaceful two‑bedroom lake retreat on Lake Marion’s Chapel Branch. Perfect for families or friends, your spacious unit puts 311 miles of shoreline and top fishing—home to 30+ species—within easy reach. Explore Santee State Park for hiking and mountain biking, tee off at one of three nearby golf courses, or simply relax lakeside and take in the views. Comfortable, well‑appointed, and ideal for outdoor adventures.

Superhost
Hotel room in Santee
New place to stay

Deluxe 2-Bedroom on Lake Marion

Escape the ordinary at this peaceful two‑bedroom lake retreat on Lake Marion’s Chapel Branch. Perfect for families or friends, your spacious unit puts 311 miles of shoreline and top fishing—home to 30+ species—within easy reach. Explore Santee State Park for hiking and mountain biking, tee off at one of three nearby golf courses, or simply relax lakeside and take in the views. Comfortable, well‑appointed, and ideal for outdoor adventures.

Superhost
Hotel room in Santee

2 BR Deluxe at Lake Marion

When a trip calls for water and the ocean won’t do, a lake retreat is just the thing. Explore South Carolina’s largest lake with 311 miles of stunning shoreline or discover other adventures like mountain biking or hiking in nearby Santee State Park. Anglers will love fishing on Lake Marion, which is home to more than 30 species of fish, and if golf is more your thing, there are three golf courses within 1 mile of the resort.

Guest favorite
Hotel room in Summerton
4.91 out of 5 average rating, 11 reviews

Cozy Lakeside Studio with Serene Views

<p data-start="150" data-end="497">Relax in this charming lakeside studio, perfect for a romantic getaway or peaceful retreat. The space sleeps 2 and includes a comfortable queen bed, private bathroom, TV, and kitchenette with mini fridge, microwave, and hot plate. Enjoy serene lake views and a charcoal grill for laid-back evenings. Photos are representative and may vary by unit.</p>

Popular amenities for Clarendon County hotels