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Vacation rentals in Cameron County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Cameron County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in Harlingen
4.91 out of 5 average rating, 102 reviews

Sage House-$0 cleaning fee! SALE TODAY 5/28/26

Stylish and 5 mins. from airport! Sage house embodies relax and zen. Creature comforts include tv’s in every room including a 85 inch in the main lounge and PlayStation 5. Premium Keurig machine stocked with your faves! Hybrid beds w/1,200 thread count sheets. Located blocks from the most important intersection in Harlingen, Ed Carey and Sunshine Strip. Major restaurants/shops nearby,and the hospital district and UTRGV, 2 blocks away. It will be your favorite home away from home in Harlingen!

Top guest favorite
Guesthouse in San Benito
5 out of 5 average rating, 26 reviews

Cozy Countryside Cottage

Welcome to Bethel Ranch, a peaceful rural escape just a short drive from South Padre Island and Starbase. Surrounded by open skies and quiet countryside, this calm, stylish stay offers privacy, comfort, and a slower pace. Enjoy cozy amenities, thoughtful touches, and a relaxing atmosphere ideal for unwinding after beach days, rocket launches, or coastal exploring. A serene retreat designed to help you disconnect, recharge, and enjoy a refreshing getaway. Ideal for guests seeking peace and rest.

Top guest favorite
The open-concept living area features a comfortable gray sofa, decorative accent pillows, and a large area rug. A stone fireplace is set against a wooden wall. A stylish coffee table is surrounded by two poufs. The space is bathed in natural light from large windows.
Loft in Brownsville
4.99 out of 5 average rating, 116 reviews

The Boho in BTX - Adults Only

The Boho is a unique space inside a quiet, tropical complex in a residential neighborhood. The space boasts a high ceiling with large windows that allow incredible natural light to fill the space with an airy, zen vibe. Enjoy living like a BTX local in this boho hideaway located in the heart of the city. This the ideal space for business travelers looking for a comfortable, quiet space to unwind while still being just a quick Uber ride to the local art scene, dining and entertainment.

Guest favorite
The exterior of the cozy casita is shown, featuring a modern grey facade with large windows that allow natural light to enter. A welcoming black front door framed by two potted plants leads to a front porch with steps. The surrounding yard is tidy and inviting.
Tiny home in Los Fresnos
4.96 out of 5 average rating, 112 reviews

The Little House

This 1 bedroom cozy casita is located in Los Fresnos,TX. It's perfect for individuals and couples . It can comfortably accommodate 2 ppl. We are conveniently located between South Padre Island,Brownsville,Harlingen and to all four international bridge crossings from Los Indios to Brownsville.For the enjoyment of all birdwatchers we are located in the middle of 3 major wildlife refugees. One being Laguna Atascosa National Wildlife Refuge.We're also 6miles away from windmill farm.

Guest favorite
A modern kitchen is highlighted by sleek stainless steel appliances and elegant quartz countertops. Four light-colored bar stools are positioned at a spacious island, complemented by a stylish pendant light overhead. Subtle decorative elements add warmth to the contemporary design.
Home in Brownsville
4.98 out of 5 average rating, 55 reviews

The Bluebonnet Peak

The Bluebonnet Peak is fully equipped to be your home-away-from-home. A beautifully modern duplex house centrally located near major stores, restaurants, and 30 min away from SPI. It offers a calming ambiance with spacious 3 bedroom/2 bathroom home and a trail next door. The kitchen is furnished with stainless steel appliances, quartz countertops, and of course, all you need for coffee each morning! Amenities are offered and include a private washing room for your personal use.

Guest favorite
The exterior of a blue house is presented, featuring a welcoming entrance with a white door and wooden accents. A decorative sign displays the house number '450'. A small window with white trim complements the design, while the surrounding area is neatly maintained.
Home in San Benito
5 out of 5 average rating, 19 reviews

The New Comfy Blue Cottage

Kick back and relax in this NEW, clean, calm, stylish space, will all the amenities that you may need, 2 large bedrooms W/SmartTV 1 Bathroom with a large living area W/Smart 55"TV, central air , washer and dryer. One block from Heavin Resaca Trail park in San Benito, HEB Walmart and restaurants, centrally located a few minutes drive from Harlingen and North Brownsville 45 Minutes drive to South Padre Island or SpaceX, you will be happy you choose to stay here.

Top guest favorite
A spacious master bedroom is furnished with a king-size bed, adorned with neutral linens. Two bedside lamps illuminate the space, and a large ceiling fan provides airflow. A desk and chair are positioned against one wall, with a view into the connected kitchen area.
Guest suite in Los Fresnos
5 out of 5 average rating, 400 reviews

Peaceful/Private Apartment with separate entrance

A peaceful haven and home away from home- that's how many have described this one bedroom, one bath apartment (700 sq ft), with fully-furnished kitchen, private patio and separate entrance . We tried to incorporate everything a person would need to be comfortable. We look forward to welcoming you to the Los Fresnos/South Padre Island/Brownsville area! This apartment is connected to our home and hosts live on premises, but it has its own private entrance.

Top guest favorite
Home in Rio Hondo
5 out of 5 average rating, 46 reviews

Casita Azul

Bring the whole family to this great place with lots of room. Casita Azul provides plenty of space indoors and outdoors. The house sits just outside of Rio Hondo city limits which gives you a touch of country living. We are located 5 minutes away from Rio Hondo, 10 minutes from San Benito, 18 minutes from Harlingen Airport, 25 minutes from Brownsville, 50 minutes from Space X, 25 minutes from Arroyo City and 50 minutes away from South Padre Island.

Top guest favorite
A charming tiny home is framed by soft evening light, with string lights illuminating the outdoor space. A covered porch offers access to the front door, while a neatly landscaped yard features grass and a paved area. A wooden fence surrounds the property for added privacy.
Tiny home in Brownsville
4.98 out of 5 average rating, 175 reviews

La Jefferson: Historic District

Welcome! This tiny home in the historic district is close to parks, eateries, museums, shops, the farmers market, and the Gladys Porter Zoo. Explore downtown, venture into Mexico, visit the Island, SpaceX, or simply unwind at home. Inside, find a living area and kitchen, a bedroom with a queen bed, TV, and reading corner. Step onto the back porch for views of the lit patio and private fenced yard. Book your stay now! Can't wait to have you over!

Guest favorite
A charming rental home features a light grey exterior with turquoise doors and trim. A covered porch is adorned with white railings, while lush greenery frames the entrance. The surrounding yard is neatly maintained, providing a welcoming atmosphere for guests.
Cottage in Brownsville
4.87 out of 5 average rating, 384 reviews

Jefferson House A - Brownsville Historic District

Cozy rental home located in Brownsville Historic District. Built in the early 1900's and remodeled recently. This beautiful piece of local history is located within walking distance of some of the most visited amenities in Brownsville, such as, Washington Park (Home of the Sombrero Fest), the Gladys Porter Zoo, Market Square, The Brownsville Museum of Fine Arts and UTRGV. South Padre Island & Boca Chica Beach are just 25 minutes away.

Guest favorite
A wooden dock extends over the water, featuring a picnic table and benches ideal for outdoor dining. Lush green grass leads up to the entrance of the cabin, surrounded by trees and open sky, creating a serene environment for relaxation.
Cabin in Rio Hondo
4.88 out of 5 average rating, 164 reviews

Docket - Waterfront Fishing Cabin

The cabin’s purpose is comfort and relaxation - comfy sofas, pool table, spacious accommodations, and a direct connection with the outdoors. In the late evening/early morning enjoy go outside on the dock to fish or sit and watch the traffic on the Arroyo. Great place to destress. *Due to the nature of the area, there are frequent internet, water, and power outages.

Guest favorite
A modern kitchen with a central island includes four high-backed stools. Sleek cabinetry and a stainless steel appliance setup enhance functionality. Natural light fills the space through large windows, creating a bright and inviting atmosphere.
Apartment in Brownsville
4.97 out of 5 average rating, 98 reviews

Serene Townhome in Brownsville

This quiet and peaceful spot is ideal for families and friends to stay and relax. The whole group will enjoy easy access to everything from this centrally located place. It's spacious, with modern amenities like high-speed internet and a fully equipped kitchen. It's the perfect place for groups wanting convenience, comfort, and a taste of city living.

Popular amenities for Cameron County vacation rentals

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