House vacation rentals in Antioquia

Find and book unique houses on Airbnb

Top-rated house rentals in Antioquia

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Guatapé

4.89 out of 5 average rating, 415 reviews

Private house, Lake access Spa experiences

100% privado. Este lugar especial se encuentra en una de las zonas más hermosa de Colombia, rodeado de una vista lacustre 15 km Despertarás en medio de la belleza natural, refrescando tu mente y alma al instante. Hemos creado experiencias a medida,cocina tradicional , chef , experiencias acuaticas y nuestro Spa qué llegara hasta ti para ofrecerte el momento unico qué tu mereces . nuestro concepto es orgánico,confort y privacidad disfruta de la piscina natural y reconecta con la naturaleza.

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Top guest favorite

The interior space features a striking vaulted ceiling with wooden beams, creating a sense of openness. Large glass windows highlight panoramic views of the surrounding landscape. Comfortable seating is arranged near a wooden coffee table, while a kitchen area is visible in the background.

Home

4.95 out of 5 average rating, 256 reviews

Lakefront Arc House-10 Min to Guatape, Lake Access

* The lake levels are back & the docks are floating! * Experience the awe-inspiring Arc House, an architecturally designed gem on a private bay, just 10 minutes from Guatape. Glass walls, 20-foot ceilings, and panoramic nature views make it truly unique. The house features 2 queen bedrooms, ensuite bathrooms, balconies, and a sofa in the living area to accommodate a total of 6 people. The high-quality kitchen is a chef's dream, complemented by a dining table for 6 and a lake-view balcony.

ValueFamilyQuiet

Top guest favorite

A spacious outdoor deck features a wooden floor and a covered lounge area with seating and a hot tub. The backdrop showcases a stunning view of the Peñol Rock and surrounding lush mountains, while a serene waterway flows nearby.

Home in Peñol

4.98 out of 5 average rating, 123 reviews

New Luxury Cabin Jacuzzi Sauna Fireplace Best View

Spacious home featuring two Queen-size beds, one double bed, and two single beds, with an additional sofa bed that can be used as a double bed! Everything you could wish for in a property with the best view of the beautiful mountains and the iconic Peñol Rock, one of the most visited attractions in Antioquia. The amenities speak for themselves in a central & easily accessible location, reachable by car, and just a two-block walk to the nearby marina so you can rent my Jetski & boat!

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Guest favorite

Home in Guatapé

4.83 out of 5 average rating, 220 reviews

A little house with access to the lake and a view of the stone, Guatape

Your stay includes free use of kayaks and bicycles (with a refundable deposit), so you can enjoy the reservoir and its surroundings. This authentic little Antioquia house is perfect for couples or small groups looking for a place full of charm. As the reviews show, it is a magical space that exceeds expectations and is usually even more beautiful than what the photos show. Private access to the reservoir, large green areas, and close to the Piedra del Peñol and the main road.

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Top guest favorite

An outdoor area is illuminated at night, featuring a private pool with a water feature and a jacuzzi. A spacious seating arrangement with a dining table is visible beside the pool, with the modern house in the background showcasing large windows and an open design.

Home in Santa Fe de Antioquia

4.97 out of 5 average rating, 114 reviews

Modern Villa with a pool and private Jacuzzi!

Modern house with a swimming pool and private Jacuzzi, (Rates from 6 to 10 people), with luxury finishes, spacious and fully equipped for a very comfortable stay. An ideal place to relax, unwind and share unforgettable moments with family, as a couple and with friends. Located two blocks from the main park of Santa Fe de Antioquia, a magical place of great historical and cultural richness, its colonial architecture and well-preserved cobblestone streets are a national heritage.

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Superhost

Home in Sopetrán

4.84 out of 5 average rating, 135 reviews

Casa Utopia Pool View BBQ Air Conditioning and Wifi

Casa Utopía is the mix you're looking for: 🏞️Excellent views of the Antioquia Mountains 🏊‍♂️ Private pool and BBQ - Barrel Grill ❄️ Air conditioning in all 3 bedrooms (20 Guests) 💻Fast Wi-Fi (Starlink) and space to work. Spend the day between dips, barbecues, and hammock naps. At night, movies on Smart TV and clear skies. Quiet location 10 minutes from Sopetrán Park and 20 minutes from Santa Fé de Antioquia, with easy access and total privacy. Secure your dates!

LocationValueCleanliness

Top guest favorite

A wooden jacuzzi is positioned on a deck, offering sweeping views of green mountains. A basket filled with colorful towels sits nearby, complementing the serene setting. Lush plants frame the scene, enhancing the natural ambiance.

Home in Titiribí

4.93 out of 5 average rating, 126 reviews

Casa Ceiba - The Forest

Discover the magic of Titiribí, Antioquia, in our spectacular house with unparalleled views. Relax in the Jacuzzi or cool off in the pool while enjoying a unique natural setting. This cozy space is perfect for couples or friends. With spacious common areas and all the amenities you need, your stay will be unforgettable. Come and live an experience of tranquility and beauty in the middle of the mountains! Book now and make your trip special

LocationValueQuiet

Guest favorite

A warm and inviting living area features an elegantly designed wooden dining table and chairs. Natural light filters through vertical blinds, creating soft patterns on the floor. A mirror reflects the space, while a wall-mounted television and decorative elements add modern touches.

Home in Laureles

4.9 out of 5 average rating, 167 reviews

NEW Beautiful Loft in Laureles with A/C and WI-FI

Let yourself be amazed by our cozy, stylish, and visually striking space! Located in a peaceful yet vibrant, walkable Laureles neighborhood, Amanda is the perfect home base for your Medellín stay. With high-speed Wi-Fi and AC, it’s ideal for remote work. Just one block from a main avenue, enjoy easy access to public transport, supermarkets, cafes, and restaurants. A warm, comfortable, and modern stay awaits you!

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Superhost

A charming house with a classic terracotta roof is set amidst rolling mountains. Surrounded by greenery, the exterior features a spacious porch with hanging plants. A vehicle is parked nearby on the well-maintained grassy area, providing easy access to the property.

Home in Barbosa

4.89 out of 5 average rating, 232 reviews

House with an Incredible View - 7 nights 15% off

Beautiful house in the mountains. 42 km (26 miles) from Medellín, (40 minutes from the exit of Bello) Please note there is one (1) toll on the route. Ideal for resting or working away from the city. A private place with great spaces for outdoor activities, away from noise and stress. Thanks to our guests' recommendations: - We installed new mattresses - We added Wi-Fi to our property

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Superhost

Home in Carmen de Viboral

4.86 out of 5 average rating, 109 reviews

Entire farmhouse | Nature & relax in el carmen v

Embark on the authentic experience of the Colombian countryside in our beautiful estate, where nature and hospitality come together to offer you unforgettable vacations. Wake up to the wonderful singing and sighting of local birds, while the tranquility and connection with the nature, culture, and biodiversity of the region ensure unforgettable moments with your family and friends.

LocationFamilyHeating

Guest favorite

Home in Santa Fe de Antioquia

4.88 out of 5 average rating, 174 reviews

Your resting place in Santafé de Antioquia

Our rest house offers comfort and style with 2 bedrooms, 2 bathrooms and an atmosphere designed to share with those you love the most. Residential area, safe and a few minutes from the historic center, easy access to everything you need 🌿🏠☀️ publication cost valid for 2 people, capacity for a maximum of 5 people. THANK YOU FOR CHOOSING US 🏠🌿 Important: We are not a hotel 🤗

LocationFamilyKitchen

Guest favorite

A serene outdoor area features a tranquil swimming pool surrounded by lush greenery. Vibrant flowers and tropical plants frame the pool area, while a blue awning adds shade. The scene showcases the natural beauty of the environment, enhancing a peaceful retreat.

Home in Sopetrán

4.84 out of 5 average rating, 101 reviews

Entire Private House in Sopetran, Antioquia.

Disconnect in the middle of nature. You can enjoy the tranquility and privacy that this incredible property offers you. Share a weekend in the wonderful climate of Sopetran with your family, friends or partner. You'll be located just 10 minutes from the main park, 30 minutes from Santa Fe de Antioquia, and 50 minutes from Medellín.

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