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House vacation rentals in Antioquia

Find and book unique houses on Airbnb

Top-rated house rentals in Antioquia

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Guatapé
4.89 out of 5 average rating, 412 reviews

Private house, Lake access Spa experiences

100% privado. Este lugar especial se encuentra en una de las zonas más hermosa de Colombia, rodeado de una vista lacustre 15 km Despertarás en medio de la belleza natural, refrescando tu mente y alma al instante. Hemos creado experiencias a medida,cocina tradicional , chef , experiencias acuaticas y nuestro Spa qué llegara hasta ti para ofrecerte el momento unico qué tu mereces . nuestro concepto es orgánico,confort y privacidad disfruta de la piscina natural y reconecta con la naturaleza.

Guest favorite
An infinity pool overlooks lush green hills and a serene dam, providing panoramic views of the surrounding natural landscape. The vibrant sky contrasts with the tranquil water, inviting guests to immerse themselves in the picturesque environment.
Home in San Rafael
4.9 out of 5 average rating, 145 reviews

15-Bedroom Finca Infinity Pool | San Rafael

✅ All fees included • ⚡ Instant booking • 📆 Flexible cancellation Exclusive 86-acre private 15-bedroom finca with infinity pool in San Rafael. Perfect for family reunions, weddings, yoga retreats & corporate getaways. Only one group at a time with breathtaking mountain & reservoir views. • Min 10 | Sleeps up to 48 • Infinity pool (180° views) + jacuzzi & sauna • 15 bedrooms | 18 baths • Full kitchen for 48 • Starlink Wi-Fi | Solar power Up to 16 on Airbnb. 17–48+ see “How to Book” below.

Top guest favorite
An outdoor seating area is shown, featuring a small round table surrounded by two chairs. A warm fire is seen in a metal fire pit, while rain falls lightly, creating a cozy ambiance. Lush greenery borders the space, with soft lighting illuminating the scene.
Home in Rionegro
4.9 out of 5 average rating, 100 reviews

A small farm 2 minutes away from Rionegro Airport

Finquita La Fortuna, ideal for being close to Rionegro's JMC MDE Airport, just 2 minutes away, with convenient 24-hour transportation; 15 minutes from Medellín and Santa Elena; Arví Park; a safe and central area; close to the María Madre de Dios parish; La Mal Sentada Túnel restaurant; Capitulo by Relato restaurant; La Matriarca restaurant; private entrance; private parking; campfire area; BBQ or charcoal grill; nearby minimarket, pharmacies, shopping centers, and a horseback riding center.

Guest favorite
A spacious outdoor deck features a wooden floor and a covered lounge area with seating and a hot tub. The backdrop showcases a stunning view of the Peñol Rock and surrounding lush mountains, while a serene waterway flows nearby.
Home in Peñol
4.98 out of 5 average rating, 121 reviews

New Luxury Cabin Jacuzzi Sauna Fireplace Best View

Spacious home featuring two Queen-size beds, one double bed, and two single beds, with an additional sofa bed that can be used as a double bed! Everything you could wish for in a property with the best view of the beautiful mountains and the iconic Peñol Rock, one of the most visited attractions in Antioquia. The amenities speak for themselves in a central & easily accessible location, reachable by car, and just a two-block walk to the nearby marina so you can rent my Jetski & boat!

Top guest favorite
An outdoor area is illuminated at night, featuring a private pool with a water feature and a jacuzzi. A spacious seating arrangement with a dining table is visible beside the pool, with the modern house in the background showcasing large windows and an open design.
Home in Santa Fe de Antioquia
4.97 out of 5 average rating, 114 reviews

Modern Villa with a pool and private Jacuzzi!

Modern house with a swimming pool and private Jacuzzi, (Rates from 6 to 10 people), with luxury finishes, spacious and fully equipped for a very comfortable stay. An ideal place to relax, unwind and share unforgettable moments with family, as a couple and with friends. Located two blocks from the main park of Santa Fe de Antioquia, a magical place of great historical and cultural richness, its colonial architecture and well-preserved cobblestone streets are a national heritage.

Guest favorite
Home in Guatapé
4.82 out of 5 average rating, 217 reviews

A little house with access to the lake and a view of the stone, Guatape

Your stay includes free use of kayaks and bicycles (with a refundable deposit), so you can enjoy the reservoir and its surroundings. This authentic little Antioquia house is perfect for couples or small groups looking for a place full of charm. As the reviews show, it is a magical space that exceeds expectations and is usually even more beautiful than what the photos show. Private access to the reservoir, large green areas, and close to the Piedra del Peñol and the main road.

Superhost
Home in Santa Fe de Antioquia
4.69 out of 5 average rating, 13 reviews

Farm near Medellín

Residence 40 minutes from Medellín, warm climate. Luxury retreat near Medellín in a private and exclusive setting. Enjoy an infinity pool, hot tub, fire pit, BBQ, and outdoor movie theater. Designer house with 3 bedrooms, 6 beds, and 4 bathrooms. Fully equipped gourmet kitchen, built-in sound system, and ideal spaces for unique experiences. Perfect for premium stays or private events (by reservation). Security with external monitoring and 24/7 housekeeping service.

Top guest favorite
A wooden jacuzzi is positioned on a deck, offering sweeping views of green mountains. A basket filled with colorful towels sits nearby, complementing the serene setting. Lush plants frame the scene, enhancing the natural ambiance.
Home in Titiribí
4.93 out of 5 average rating, 125 reviews

Casa Ceiba - The Forest

Discover the magic of Titiribí, Antioquia, in our spectacular house with unparalleled views. Relax in the Jacuzzi or cool off in the pool while enjoying a unique natural setting. This cozy space is perfect for couples or friends. With spacious common areas and all the amenities you need, your stay will be unforgettable. Come and live an experience of tranquility and beauty in the middle of the mountains! Book now and make your trip special

Top guest favorite
A modern concrete home is nestled among lush greenery, showcasing its unique architectural design. The multi-level structure features large windows that provide expansive views of the surrounding landscape, while a spacious rooftop terrace offers outdoor seating against a backdrop of mountains.
Home
4.95 out of 5 average rating, 241 reviews

Architectural Award Winning Home - Lakeside, Views

Winner of the SARA NY Design Award of Honor, & recently featured in AXXIS Architectural Magazine, this hilltop hand poured concrete home is located in the most exclusive area of Guatape, 10 min from town 360’ views, lake access & only 3 other properties on the 4 acre site, the setting is quiet & private Enjoy sunset views from the rooftop balcony or plunge bath. Note: Access is a 100 meter path with a moderate climb

Superhost
A charming house with a classic terracotta roof is set amidst rolling mountains. Surrounded by greenery, the exterior features a spacious porch with hanging plants. A vehicle is parked nearby on the well-maintained grassy area, providing easy access to the property.
Home in Barbosa
4.89 out of 5 average rating, 232 reviews

House with an Incredible View - 7 nights 15% off

Beautiful house in the mountains. 42 km (26 miles) from Medellín, (40 minutes from the exit of Bello) Please note there is one (1) toll on the route. Ideal for resting or working away from the city. A private place with great spaces for outdoor activities, away from noise and stress. Thanks to our guests' recommendations: - We installed new mattresses - We added Wi-Fi to our property

Guest favorite
Home in Carmen de Viboral
4.86 out of 5 average rating, 107 reviews

Entire farmhouse | Nature & relax in el carmen v

Embark on the authentic experience of the Colombian countryside in our beautiful estate, where nature and hospitality come together to offer you unforgettable vacations. Wake up to the wonderful singing and sighting of local birds, while the tranquility and connection with the nature, culture, and biodiversity of the region ensure unforgettable moments with your family and friends.

Guest favorite
Home in Santa Fe de Antioquia
4.88 out of 5 average rating, 173 reviews

Your resting place in Santafé de Antioquia

Our rest house offers comfort and style with 2 bedrooms, 2 bathrooms and an atmosphere designed to share with those you love the most. Residential area, safe and a few minutes from the historic center, easy access to everything you need 🌿🏠☀️ publication cost valid for 2 people, capacity for a maximum of 5 people. THANK YOU FOR CHOOSING US 🏠🌿 Important: We are not a hotel 🤗

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