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House vacation rentals in Antioquia

Find and book unique houses on Airbnb

Top-rated house rentals in Antioquia

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Fredonia
4.95 out of 5 average rating, 42 reviews

Hacienda Naya: Pool, Views & Waterfalls

Escape to Hacienda Naya, a private coffee-farm retreat with valley views, waterfalls, a pool, and space for up to 13 guests. Some mornings, the hacienda feels as if it’s floating above the clouds. Swim with a view, wake to birdsong, breathe the mountain air, tour the coffee fields, or immerse yourself in the waterfall’s sound, mist, and calm. Guests often arrive with plans, then slow down into quiet nights, long views, and meals prepared by an optional local cook, so everyone can truly relax.

Guest favorite
Home in Guatape
4.89 out of 5 average rating, 412 reviews

Private house, Lake access Spa experiences

100% privado. Este lugar especial se encuentra en una de las zonas más hermosa de Colombia, rodeado de una vista lacustre 15 km Despertarás en medio de la belleza natural, refrescando tu mente y alma al instante. Hemos creado experiencias a medida,cocina tradicional , chef , experiencias acuaticas y nuestro Spa qué llegara hasta ti para ofrecerte el momento unico qué tu mereces . nuestro concepto es orgánico,confort y privacidad disfruta de la piscina natural y reconecta con la naturaleza.

Guest favorite
An infinity pool overlooks lush green hills and a serene dam, providing panoramic views of the surrounding natural landscape. The vibrant sky contrasts with the tranquil water, inviting guests to immerse themselves in the picturesque environment.
Home in San Rafael
4.9 out of 5 average rating, 144 reviews

15-Bedroom Finca Infinity Pool | San Rafael

✅ All fees included • ⚡ Instant booking • 📆 Flexible cancellation Exclusive 86-acre private 15-bedroom finca with infinity pool in San Rafael. Perfect for family reunions, weddings, yoga retreats & corporate getaways. Only one group at a time with breathtaking mountain & reservoir views. • Min 10 | Sleeps up to 48 • Infinity pool (180° views) + jacuzzi & sauna • 15 bedrooms | 18 baths • Full kitchen for 48 • Starlink Wi-Fi | Solar power Up to 16 on Airbnb. 17–48+ see “How to Book” below.

Top guest favorite
The interior space features a striking vaulted ceiling with wooden beams, creating a sense of openness. Large glass windows highlight panoramic views of the surrounding landscape. Comfortable seating is arranged near a wooden coffee table, while a kitchen area is visible in the background.
Home in Antioquia
4.94 out of 5 average rating, 249 reviews

Lakefront Arc House-10 Min to Guatape, Lake Access

* The lake levels are back & the docks are floating! * Experience the awe-inspiring Arc House, an architecturally designed gem on a private bay, just 10 minutes from Guatape. Glass walls, 20-foot ceilings, and panoramic nature views make it truly unique. The house features 2 queen bedrooms, ensuite bathrooms, balconies, and a sofa in the living area to accommodate a total of 6 people. The high-quality kitchen is a chef's dream, complemented by a dining table for 6 and a lake-view balcony.

Superhost
Home in Santa Fe de Antioquia
4.84 out of 5 average rating, 62 reviews

Cabin in Santa Fe de Antioquia

Escape to this beautiful estate just 7 minutes from the historic center of Santa Fe de Antioquia, near the iconic Puente de Occidente. Relax while you’re on the terrace, in the pool, or in the hot tub, with a spectacular view of the mountains and an environment surrounded by nature. Capacity for 12 people. It has air conditioning, Wi-Fi, a fully equipped kitchen, a BBQ area, furnished spaces, and private parking. Ideal for rest and spending time with family, friends, or your partner.

Guest favorite
A spacious outdoor deck features a wooden floor and a covered lounge area with seating and a hot tub. The backdrop showcases a stunning view of the Peñol Rock and surrounding lush mountains, while a serene waterway flows nearby.
Home in El Peñol
4.98 out of 5 average rating, 119 reviews

New Luxury Cabin Jacuzzi Sauna Fireplace Best View

Spacious home featuring two Queen-size beds, one double bed, and two single beds, with an additional sofa bed that can be used as a double bed! Everything you could wish for in a property with the best view of the beautiful mountains and the iconic Peñol Rock, one of the most visited attractions in Antioquia. The amenities speak for themselves in a central & easily accessible location, reachable by car, and just a two-block walk to the nearby marina so you can rent my Jetski & boat!

Guest favorite
Home in Guatape
4.82 out of 5 average rating, 217 reviews

A little house with access to the lake and a view of the stone, Guatape

Your stay includes free use of kayaks and bicycles (with a refundable deposit), so you can enjoy the reservoir and its surroundings. This authentic little Antioquia house is perfect for couples or small groups looking for a place full of charm. As the reviews show, it is a magical space that exceeds expectations and is usually even more beautiful than what the photos show. Private access to the reservoir, large green areas, and close to the Piedra del Peñol and the main road.

Top guest favorite
An outdoor area is illuminated at night, featuring a private pool with a water feature and a jacuzzi. A spacious seating arrangement with a dining table is visible beside the pool, with the modern house in the background showcasing large windows and an open design.
Home in Santa Fe de Antioquia
4.97 out of 5 average rating, 114 reviews

Modern Villa with a pool and private Jacuzzi!

Modern house with a swimming pool and private Jacuzzi, (Rates from 6 to 10 people), with luxury finishes, spacious and fully equipped for a very comfortable stay. An ideal place to relax, unwind and share unforgettable moments with family, as a couple and with friends. Located two blocks from the main park of Santa Fe de Antioquia, a magical place of great historical and cultural richness, its colonial architecture and well-preserved cobblestone streets are a national heritage.

Superhost
Home in Santa Fe de Antioquia
4.69 out of 5 average rating, 13 reviews

Farm near Medellín

Residence 40 minutes from Medellín, warm climate. Luxury retreat near Medellín in a private and exclusive setting. Enjoy an infinity pool, hot tub, fire pit, BBQ, and outdoor movie theater. Designer house with 3 bedrooms, 6 beds, and 4 bathrooms. Fully equipped gourmet kitchen, built-in sound system, and ideal spaces for unique experiences. Perfect for premium stays or private events (by reservation). Security with external monitoring and 24/7 housekeeping service.

Guest favorite
Home in Marinilla
4.89 out of 5 average rating, 9 reviews

Country house one hour from Medellín

Unwind for a few days, enjoy the sound of birds and frogs, and walk along trails surrounded by crops and forests in a cool climate, just an hour from Medellín, an hour from Guatapé, and a few minutes from small tourist towns and rivers in eastern Antioquia. You will have easy access to markets, cafes, and restaurants, and you will be 20 minutes from the San Nicolás shopping center. The property is in a safe and very quiet area, perfect for rest and remote work.

Top guest favorite
A wooden jacuzzi is positioned on a deck, offering sweeping views of green mountains. A basket filled with colorful towels sits nearby, complementing the serene setting. Lush plants frame the scene, enhancing the natural ambiance.
Home in Titiribí
4.93 out of 5 average rating, 125 reviews

Casa Ceiba - The Forest

Discover the magic of Titiribí, Antioquia, in our spectacular house with unparalleled views. Relax in the Jacuzzi or cool off in the pool while enjoying a unique natural setting. This cozy space is perfect for couples or friends. With spacious common areas and all the amenities you need, your stay will be unforgettable. Come and live an experience of tranquility and beauty in the middle of the mountains! Book now and make your trip special

Superhost
A charming house with a classic terracotta roof is set amidst rolling mountains. Surrounded by greenery, the exterior features a spacious porch with hanging plants. A vehicle is parked nearby on the well-maintained grassy area, providing easy access to the property.
Home in Barbosa
4.89 out of 5 average rating, 232 reviews

House with an Incredible View - 7 nights 15% off

Beautiful house in the mountains. 42 km (26 miles) from Medellín, (40 minutes from the exit of Bello) Please note there is one (1) toll on the route. Ideal for resting or working away from the city. A private place with great spaces for outdoor activities, away from noise and stress. Thanks to our guests' recommendations: - We installed new mattresses - We added Wi-Fi to our property

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